Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Raymond C. Sowder"'
Autor:
Oleg Chertov, Ning Zhang, Xin Chen, Joost J Oppenheim, Jacek Lubkowski, Connor McGrath, Raymond C Sowder, Bruce J Crise, Anatoli Malyguine, Michele A Kutzler, Amber D Steele, Earl E Henderson, Thomas J Rogers
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e14474 (2011)
The sequential interaction of the envelope glycoprotein of the human immunodeficiency virus type 1 (HIV-1) with CD4 and certain chemokine coreceptors initiates host cell entry of the virus. The appropriate chemokines have been shown to inhibit viral
Externí odkaz:
https://doaj.org/article/c33e88f88d76462f85eb5258f040392a
Autor:
Raymond C. Sowder, Abdul Waheed, Eric O. Freed, Carl P. Schaffner, Elena Chertova, James D. Roser, Sherimay D. Ablan
Publikováno v:
Journal of Virology. 84:3121-3126
We previously reported that human immunodeficiency virus type 1 (HIV-1) develops resistance to the cholesterol-binding compound amphotericin B methyl ester (AME) by acquiring mutations (P203L and S205L) in the cytoplasmic tail of the transmembrane en
Autor:
Robert J. Gorelick, Raymond C. Sowder, James A. Thomas, David R. Morcock, Louis E. Henderson, Bruce Crise
Publikováno v:
Virology. 375:148-158
Selective inactivation of critical cysteine residues in human immunodeficiency virus type one (HIV-1) was observed after treatment with 4-vinylpyridine (4-VP), with and without the membrane-permeable metal chelator N,N,N′,N′-tetrakis(2-pyridylmet
Autor:
Roberta Gardella, Toshiyuki Mori, Scott Bringans, James B. Mcmahon, Raymond C. Sowder, Shannon Berg, Jim A. Turpin, Pamela Cochran, Barry R. O'Keefe, Robert W. Buckheit, Michael R. Boyd
Publikováno v:
Journal of Biological Chemistry. 280:9345-9353
Griffithsin (GRFT), a novel anti-HIV protein, was isolated from an aqueous extract of the red alga Griffithsia sp. The 121-amino acid sequence of GRFT has been determined, and biologically active GRFT was subsequently produced by expression of a corr
Autor:
Michael R. Boyd, Tawnya C. McKee, Gregory M. L. Patterson, Roberta S. Gardella, Lewis K. Pannell, Karen Watson, Heidi R. Bokesch, Raymond C. Sowder, Robert W. Buckheit, Barry R. O'Keefe, Jim A. Turpin
Publikováno v:
Biochemistry. 42:2578-2584
A new anti-HIV protein, scytovirin, was isolated from aqueous extracts of the cultured cyanobacterium Scytonema varium. The protein displayed potent anticytopathic activity against laboratory strains and primary isolates of HIV-1 with EC50 values ran
Autor:
David E. Ott, Kunio Nagashima, Julian Adams, Raymond C. Sowder, Ulrich Schubert, Lori V. Coren
Publikováno v:
Journal of Virology. 76:3038-3044
Some retroviruses contain monoubiquitinated Gag and do not bud efficiently from cells treated with proteasome inhibitors, suggesting an interaction between the ubiquitin-proteasome system and retrovirus assembly. We examined equine infectious anemia
Autor:
Murray H. G. Munro, Raymond C. Sowder, Michael R. Boyd, Lewis K. Pannell, Tawnya C. McKee, Romila D. Charan, Michael J. Currens, Barry R. O'Keefe
Publikováno v:
Journal of Natural Products. 63:1170-1174
Aqueous extracts from the African plant Myrianthus holstii potently inhibited the infection of the T-lymphoblastoid cell line, CEM-SS, by human immunodeficiency virus-1 RF (HIV-1 RF ). The active constituent, M. holstii lectin (MHL), was purified by
Autor:
Young D. Kim, Xiao Zhen Zhou, Raymond C. Sowder, Kun Ping Lu, Lori V. Coren, David E. Ott, Louis E. Henderson, Robert J. Fisher, Donald G. Johnson, Bradley P. Kane
Publikováno v:
Virology. 266(1):42-51
Host proteins are incorporated both on and inside human immunodeficiency virus type 1 (HIV-1) virions. To identify cellular proteins inside HIV-1, virion preparations were treated by a protease-digestion technique that removes external host proteins,
Autor:
Y. F. Hallock, Lewis K. Pannell, John H. Cardellina, Raymond C. Sowder, Michael R. Boyd, Donald G. Johnson, Courtney B. Hughes, Robert Gulakowski
Publikováno v:
The Journal of Organic Chemistry. 65:124-128
Four novel anti-HIV macrocyclic peptides containing 28−31 amino acid residues, named cycloviolins A−D, have been isolated from the hitherto unstudied tropical plant Leonia cymosa. Their primary str...
Autor:
Raymond C. Sowder, Louis E. Henderson, Connor F. McGrath, Larry O. Arthur, Bradley P. Kane, Elena Chertova, Donald G. Johnson
Publikováno v:
Biochemistry. 37:17890-17897
Retroviral nucleocapsid (NC) proteins contain one or two zinc fingers (ZFs) consisting of a CCHC peptide motif that coordinates Zn(II). Mutational and biochemical analyses have shown that NC ZFs are directly involved in multiple stages of viral repli