Zobrazeno 1 - 10
of 242
pro vyhledávání: '"Raymond Baker"'
Autor:
Raymond Baker
Publikováno v:
Plant Breeders’ Rights
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::063be6b5527d384844e6688066f60ee4
https://doi.org/10.2134/asaspecpub3.c6
https://doi.org/10.2134/asaspecpub3.c6
Autor:
Kerry Starkey, Armin E. Heufelder, Marian Ludgate, Wener Joba, Marc Evans, Glynn Raymond Baker, Stephen Davies
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 88:55-59
A male type-2 diabetic, treated with the peroxisome proliferator-activated receptor (PPAR) agonist, Pioglitazone, experienced exacerbation of his thyroid eye disease (TED), which had been stable and inactive for more then 2 yr. Expansion of the orbit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::324795e7ad69d240f8e715f45eef18b8
https://doi.org/10.1210/jc.2002-020987
https://doi.org/10.1210/jc.2002-020987
Autor:
Richard G. Ball, Michael G. N. Russell, Raymond Baker, Steven R. Thomas, Jose L. Castro, Nancy N. Tsou
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :893-899
An asymmetric synthesis of the dihydrobenzofuran segment of ephedradine C has been achieved. Key steps include a chiral oxazolidinone-mediated aldol reaction to form a β-hydroxy ester, followed by a novel debenzylation and concomitant intramolecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::518248b2c4e3c0c1f697c8cfb27ee8b3
https://doi.org/10.1039/a909816j
https://doi.org/10.1039/a909816j
Publikováno v:
Tetrahedron Letters. 40:8667-8670
An asymmetric synthesis of the dihydrobenzo[b]furan segment of ephedradine C has been achieved utilising a chiral oxazolidinone in an aldol reaction to form a β-hydroxy ester, followed by a novel debenzylation and concomitant intramolecular cyclisat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eca5c93b03736a3e8f37c8f17df691d4
https://doi.org/10.1016/s0040-4039(99)01835-3
https://doi.org/10.1016/s0040-4039(99)01835-3
Autor:
Michael Rowley, Ian Collins, Howard B. Broughton, William B. Davey, Raymond Baker, Frances Emms, Rosemarie Marwood, Shil Patel, Smita Patel, C. Ian Ragan, Stephen B. Freedman, Richard Ball, Paul D. Leeson
Publikováno v:
Journal of Medicinal Chemistry. 40:2374-2385
5-(4-Chlorophenyl)-3-(1-(4-chlorobenzyl)piperidin-4-yl)pyrazole (3) was identified from screening of the Merck sample collection as a human dopamine D4 (hD4) receptor ligand with moderate affinity (61 nM) and 4-fold selectivity over human D2 (hD2) re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1edd60f700febd9c51288d528d277eb
https://doi.org/10.1021/jm970111h
https://doi.org/10.1021/jm970111h
Autor:
Sarah Grimwood, Paul D. Leeson, John A. Kemp, Christopher Moyes, Mark D. Tricklebank, Robert W. Carling, Kevin W. Moore, Raymond Baker, Alan C. Foster, George R. Marshall, Martin L. Hudson, K. L. Saywell, Duncton Matthew A J
Publikováno v:
Journal of Medicinal Chemistry. 40:754-765
4-Substituted-3-phenylquinolin-2(1H)-ones have been synthesized and evaluated in vitro for antagonist activity at the glycine site on the NMDA (N-methyl-D-aspartate) receptor and in vivo for anticonvulsant activity in the DBA/2 strain of mouse in an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da4422e5a6789e47a409d6681a5a872
https://doi.org/10.1021/jm9605492
https://doi.org/10.1021/jm9605492
Autor:
S. L. Shepheard, Josephine A. Stanton, Margaret S. Beer, Austin John Reeve, Victor G. Matassa, Francine Sternfeld, Michael I. Graham, Jeanette Longmore, Richard Alexander Jelley, Richard Hargreaves, Alexander Richard Guiblin, Leslie J. Street, Bindi Sohal, Z. Razzaque, Howard B. Broughton, Raymond Baker
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:1825-1830
Optimisation of a series of 5-(heterocyclyl)tryptamines led to the identification of the symmetrically substituted, N-4 linked 1,2,4-triazole as the best indole C-5 substituent for 5-HT1D receptor affinity and selectivity. The triazole (8) is the mos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc8a3bdfb587bc6ad4d07bf750ad82b7
https://doi.org/10.1016/0960-894x(96)00324-1
https://doi.org/10.1016/0960-894x(96)00324-1
Autor:
Raymond Baker, Howard Broughton
Publikováno v:
Phosphorus, Sulfur, and Silicon and the Related Elements. 109:337-340
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29872c25c841e62971f6d990c7a92446
https://doi.org/10.1080/10426509608545159
https://doi.org/10.1080/10426509608545159
Autor:
F.D. Tattersall, D. E. Macintyre, D. W. Williamson, Karen Elizabeth Haworth, Raymond Baker, Alan P. Watt, Margaret A. Cascieri, Tamara Ladduwahetty, Joseph M. Metzger, Eileen Mary Seward, Simon Neil Owen, Linda Elizabeth Keown, W. Rycroft, Richard Hargreaves, Christopher John Swain, S. L. Shepheard, Sharon Sadowski, Mark Stuart Chambers
Publikováno v:
Journal of Medicinal Chemistry. 39:2907-2914
The preparation of a series of N-heteroarylpiperidine ether-based human NK1 antagonists is described. Two of the compounds 3-[-(2S,3S)-3-(((3,5-bis(trifluoromethyl)phenyl)methyl)oxy)- 2-phenylpiperidino}methyl]-1,2,4-triazole (11) and 5-[¿(2S,3S)-3-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d707844fde66c1ccdbbeda0b98891503
https://doi.org/10.1021/jm9506534
https://doi.org/10.1021/jm9506534