Zobrazeno 1 - 10
of 654
pro vyhledávání: '"Raymond A. Dwek"'
Autor:
Juliane Brun, Snežana Vasiljevic, Bevin Gangadharan, Mario Hensen, Anu V. Chandran, Michelle L. Hill, J.L. Kiappes, Raymond A. Dwek, Dominic S. Alonzi, Weston B. Struwe, Nicole Zitzmann
Publikováno v:
ACS Central Science, Vol 7, Iss 4, Pp 586-593 (2021)
Externí odkaz:
https://doaj.org/article/3b1339abfdd544a394552a0f0c85a24f
Neutralizing Antibodies to SARS‐CoV‐2 Selected from a Human Antibody Library Constructed Decades Ago
Autor:
Min Qiang, Peixiang Ma, Yu Li, Hejun Liu, Adam Harding, Chenyu Min, Fulian Wang, Lili Liu, Meng Yuan, Qun Ji, Pingdong Tao, Xiaojie Shi, Zhean Li, Teng Li, Xian Wang, Yu Zhang, Nicholas C. Wu, Chang‐Chun D. Lee, Xueyong Zhu, Javier Gilbert‐Jaramillo, Chuyue Zhang, Abhishek Saxena, Xingxu Huang, Hou Wang, William James, Raymond A. Dwek, Ian A. Wilson, Guang Yang, Richard A. Lerner
Publikováno v:
Advanced Science, Vol 9, Iss 1, Pp n/a-n/a (2022)
Abstract Combinatorial antibody libraries not only effectively reduce antibody discovery to a numbers game, but enable documentation of the history of antibody responses in an individual. The severe acute respiratory syndrome coronavirus 2 (SARS‐Co
Externí odkaz:
https://doaj.org/article/930d72a539be409ea9e3ef9eab09de39
Autor:
Dan J. Sillence, Vishwajeet Puri, David L. Marks, Terry D. Butters, Raymond A. Dwek, Richard E. Pagano, Frances M. Platt
Publikováno v:
Journal of Lipid Research, Vol 43, Iss 11, Pp 1837-1845 (2002)
Glycosphingolipids are endocytosed and targeted to the Golgi apparatus, but are mistargeted to lysosomes in numerous sphingolipidoses. Substrate reduction therapy utilizes imino sugars to inhibit glucosylceramide synthase and potentially abrogate the
Externí odkaz:
https://doaj.org/article/93f0bec6ded34f598cd343de4d31939f
Autor:
Mylvaganam Jeyakumar, David Smith, Elena Eliott-Smith, Mario Cortina-Borja, Gabriele Reinkensmeier, Terry D. Butters, Thorsten Lemm, Konrad Sandhoff, V.Hugh Perry, Raymond A. Dwek, Frances M. Platt
Publikováno v:
Neurobiology of Disease, Vol 10, Iss 3, Pp 201-210 (2002)
Mouse models of the GM2 gangliosidoses, Tay–Sachs and Sandhoff disease, are null for the hexosaminidase α and β subunits respectively. The Sandhoff (Hexb−/−) mouse has severe neurological disease and mimics the human infantile onset variant.
Externí odkaz:
https://doaj.org/article/ba63622817e841bc9931fcb8d7b798ff
Autor:
Philip C. Robinson, David F. L. Liew, Helen L. Tanner, John R. Grainger, Raymond A. Dwek, Ronald B. Reisler, Lawrence Steinman, Marc Feldmann, Ling-Pei Ho, Tracy Hussell, Paul Moss, Duncan Richards, Nicole Zitzmann
The emergence of SARS-CoV-2 triggering the COVID-19 pandemic ranks as arguably the greatest medical emergency of the last century. COVID-19 has highlighted health disparities both within and between countries and will leave a lasting impact on global
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff585faf96749f4a2a50257f03c971b
https://ora.ox.ac.uk/objects/uuid:02ab2b4b-baa5-4745-a868-620ab2099852
https://ora.ox.ac.uk/objects/uuid:02ab2b4b-baa5-4745-a868-620ab2099852
Neutralizing Antibodies to SARS-CoV-2 Selected from a Human Antibody Library Constructed Decades Ago
Autor:
Chuyue Zhang, Pingdong Tao, Richard A. Lerner, Meng Yuan, Hejun Liu, Xueyong Zhu, Xiaojie Shi, Chang-Chun D Lee, Guang Yang, Yu Zhang, William James, Fulian Wang, Chenyu Min, Raymond A. Dwek, Yu Li, Adam Harding, Peixiang Ma, Ian A. Wilson, Xian Wang, Teng Li, Xingxu Huang, Qun Ji, Lili Liu, Nicholas C. Wu, Javier Gilbert-Jaramillo, Min Qiang, Zhean Li, Abhishek Saxena, Hou Wang
Publikováno v:
Advanced Science
Advanced Science, Vol 9, Iss 1, Pp n/a-n/a (2022)
Advanced Science, Vol 9, Iss 1, Pp n/a-n/a (2022)
Combinatorial antibody libraries not only effectively reduce antibody discovery to a numbers game, but enable documentation of the history of antibody responses in an individual. The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pa
Autor:
Joanna L. Miller, Nilanka Perera, Fernando O. Martinez, Andrew C Sayce, Raymond A. Dwek, Beatrice E. Tyrrell, Michelle L. Hill, Nicole Zitzmann
Publikováno v:
Immunology
Sepsis is a life‐threatening condition involving a dysregulated immune response to infectious agents that cause injury to host tissues and organs. Current treatments are limited to early administration of antibiotics and supportive care. While appe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aace6e8a5da0bf1e580c0e48a4a00e71
https://ora.ox.ac.uk/objects/uuid:f531621d-9a62-4468-9814-987b7f588487
https://ora.ox.ac.uk/objects/uuid:f531621d-9a62-4468-9814-987b7f588487
Autor:
Dominic S. Alonzi, Bevin Gangadharan, Raymond A. Dwek, Mario Hensen, Juliane Brun, J. L. Kiappes, Michelle L. Hill, Nicole Zitzmann, Anu V. Chandran, Weston B. Struwe, Snežana Vasiljević
Publikováno v:
ACS Central Science
ACS Central Science, Vol 7, Iss 4, Pp 586-593 (2021)
ACS Central Science, Vol 7, Iss 4, Pp 586-593 (2021)
Severe acute respiratory syndrome coronavirus 2 is the causative pathogen of the COVID-19 pandemic which as of March 29, 2021, has claimed 2 776 175 lives worldwide. Vaccine development efforts focus on the viral trimeric spike glycoprotein as the ma
Autor:
Raymond A. Dwek, Nicole Zitzmann, J. L. Kiappes, Juliane Brun, Anu V. Chandran, Mario Hensen, Snezana Vasiljevic, Michelle L. Hill, Weston B. Struwe, Bevin Gangadharan, Dominic S. Alonzi
Severe acute respiratory syndrome coronavirus 2 is the causative pathogen of the COVID-19 pandemic which as of Nov 15, 2020 has claimed 1,319,946 lives worldwide. Vaccine development focuses on the viral trimeric spike glycoprotein as the main target
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c85d2b4d6b65655afe1ac36ffbee9ebe
https://doi.org/10.1101/2020.11.16.384594
https://doi.org/10.1101/2020.11.16.384594
Autor:
Peixiang Ma, William James, Min C, Meng Yuan, Xueyong Zhu, Tao P, Hejun Liu, Abhishek Saxena, Raymond A. Dwek, Ian A. Wilson, Min Qiang, Wang H, Javier Gilbert-Jaramillo, Nicholas C. Wu, Xingxu Huang, Wang F, Qun Ji, Yanchun Zhang, Richard A. Lerner, Guang Yang, Chang-Chun D Lee, Lili Liu, Xiaojie Shi, Zhean Li, Adam Harding, Li Y
Combinatorial antibody libraries not only effectively reduce antibody discovery to a numbers game, but enable documentation of the history of antibody responses in an individual. The SARS-CoV-2 pandemic has prompted a wider application of this techno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a00d16e4904ca1cba6e019a61a838682
https://doi.org/10.1101/2020.11.06.370676
https://doi.org/10.1101/2020.11.06.370676