Výsledky vyhledávání - "Raymond Schinazi"

Akademický článek

An ACE2-IgG4 Fc Fusion Protein Demonstrates Strong Binding to All Tested SARS-CoV-2 Variants and Reduced Lung Inflammation in Animal Models of SARS-CoV-2 and Influenza

Autor: Emmanuel Merigeon, Dong Yang, Elizabeth Ihms, Leda Bassit, Elizabeth Fitzpatrick, Colleen Jonsson, Raymond Schinazi, David Block, Henrik Olsen

Publikováno v: Pathogens and Immunity, Vol 7, Iss 1 (2022)

Background: The continued emergence of SARS-CoV-2 variants has caused concern that a constantly evolving virus will escape vaccines and antibody therapies. New approaches are needed. Methods: We created and manufactured an ACE2 extracellular domain

Externí odkaz: https://doaj.org/article/fcc9b60707804cfbab69eb0d55de91c4

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Akademický článek

RADx Variant Task Force Program for Assessing the Impact of Variants on SARS-CoV-2 Molecular and Antigen Tests

Autor: Richard Creager, John Blackwood, Thomas Pribyl, Leda Bassit, Anuradha Rao, Morgan Greenleaf, Filipp Frank, Wilbur Lam, Eric Ortlund, Raymond Schinazi, Alexander Greninger, Mia Cirrincione, Dale Gort, Emily Kennedy, Adam Samuta, Megan Shaw, Brian Walsh, Eric Lai

Publikováno v: IEEE Open Journal of Engineering in Medicine and Biology, Vol 2, Pp 286-290 (2021)

Goal: Monitoring the genetic diversity and emerging mutations of SARS-CoV-2 is crucial for understanding the evolution of the virus and assuring the performance of diagnostic tests, vaccines, and therapies against COVID-19. SARS-CoV-2 is still adapti

Externí odkaz: https://doaj.org/article/02ba3987acda41658b1292e501fb96ab

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Akademický článek

Assessment of the Abbott BinaxNOW SARS-CoV-2 rapid antigen test against viral variants of concern

Autor: Anuradha Rao, Leda Bassit, Jessica Lin, Kiran Verma, Heather B. Bowers, Kimberly Pachura, Morgan Greenleaf, Julie Sullivan, Eric Lai, Richard S. Creager, Thomas Pribyl, John Blackwood, Anne L. Piantadosi, Raymond Schinazi, Greg S. Martin, Wilbur A. Lam

Publikováno v: iScience, Vol 25, Iss 3, Pp 103968- (2022)

Summary: As the emergence of SARS-CoV-2 variants brings the global pandemic to new levels, the performance of current rapid antigen tests against variants of concern and interest (VOC/I) is of significant public health concern. Here, we report assess

Externí odkaz: https://doaj.org/article/acaf683acb5d412396d48a6ce2af977b

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Akademický článek

Targeting Inflammation to Reduce Atherosclerotic Cardiovascular Risk in People With HIV Infection

Autor: Boghuma Titanji, Christina Gavegnano, Priscilla Hsue, Raymond Schinazi, Vincent C. Marconi

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 3 (2020)

Externí odkaz: https://doaj.org/article/ea02b53d5f5d4700bc840bce456e7ba4

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An ACE2-IgG4 Fc Fusion Protein Demonstrates Strong Binding to All Tested SARS-CoV-2 Variants and Reduced Lung Inflammation in Animal Models of SARS-CoV-2 and Influenza

Autor: Emmanuel Merigeon, Dong Yang, Elizabeth Ihms, Leda Bassit, Elizabeth Fitzpatrick, Colleen Jonsson, Raymond Schinazi, David Block, Henrik Olsen

Publikováno v: Pathogensimmunity. 7(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6365750d42670f3bcf6accee92676f1
https://pubmed.ncbi.nlm.nih.gov/36072571

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Akademický článek

1-Benzyl-2-(1H-indol-3-yl)-5-oxopyrrolidine-2-carbonitrile

Autor: Raymond Schinazi, Gasparyan Sahak, Martirosyan Ashot, Ayvazyan Armen, Rafael Tamazyan

Publikováno v: Acta Crystallographica Section E, Vol 64, Iss 2, Pp o368-o368 (2008)

In the title compound, C20H17N3O, a potential anti-human immunodeficiency virus type 1 (HIV-1) non-nucleoside reverse-transcriptase inhibitor, the pyrrolidine ring has an envelope conformation. In the crystal structure, adjacent molecules are connect

Externí odkaz: https://doaj.org/article/04eac146afdf479693870ca9f77944f4

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