Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Raymond Aitken"'
Publikováno v:
Reproduction. 161:227-238
The competition for nutrients when pregnancy coincides with continuing growth in biologically immature adolescent girls increases their risk of preterm delivery and low birthweight and is partly replicated in the overnourished adolescent sheep paradi
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
PLoS ONE, Vol 16, Iss 11, p e0259890 (2021)
PLoS ONE
PLoS ONE, Vol 16, Iss 11, p e0259890 (2021)
PLoS ONE
The competition for nutrients in overnourished and still-growing adolescent sheep negatively impacts gestation length, colostrum supply and lamb birthweight, all of which may affect neonatal morbidity and survival to weaning. Herein perinatal complic
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 2, p e0228732 (2020)
PLoS ONE, Vol 15, Iss 2, p e0228732 (2020)
Adipose tissue development begins in utero and is a key target of developmental programming. Here the influence of nutritionally-mediated prenatal growth-restriction on perirenal adipose tissue (PAT) gene expression and adipocyte phenotype in late fe
Publikováno v:
Reproduction. 156:103-119
Low birthweight is a risk factor for later adverse health. Here the impact of placentally mediated prenatal growth restriction followed by postnatal nutrient abundance on growth, glucose metabolism and body composition was assessed in both sexes at k
Publikováno v:
Reproduction (Cambridge, England). 153(4)
The influence of maternal obesity during oocyte development and its putative interaction with nutrient reserves at conception on pregnancy outcome were examined in an adolescent sheep model. Donor ewes were nutritionally managed to achieve contrastin
Autor:
DJ Carr, Anna L. David, Jacqueline Wallace, John Martin, Ian Zachary, John S. Milne, DM Peebles, Raymond Aitken
Publikováno v:
Biology of Reproduction. 94
Uterine artery (UtA) adenovirus (Ad) vector-mediated overexpression of vascular endothelial growth factor (VEGF) enhances uterine blood flow in normal sheep pregnancy and increases fetal growth in the overnourished adolescent sheep model of fetal gro
Publikováno v:
Endocrinology. 153:3147-3157
Obesity disrupts homeostatic energy balance circuits leading to insulin resistance. Here we examined in vivo peripheral and central insulin sensitivity, and whether central insensitivity in terms of the voluntary food intake (VFI) response occurs wit
Autor:
Jacqueline Wallace, Dale A. Redmer, Lawrence P. Reynolds, John S. Milne, Joel S. Caton, Mary Lynn Johnson, Pawel P. Borowicz, Raymond Aitken
Publikováno v:
Placenta. 33:114-121
When pregnant adolescent sheep are overnourished during pregnancy normal nutrient partitioning priorities to the gravid uterus are altered, leading to impaired placental development and fetal growth restriction. We hypothesized that decreasing dietar
Publikováno v:
Ultrasound in Medicine & Biology. 37:1588-1595
Our aim was to identify which ultrasound parameters can be most accurately measured and best predict ovine fetal weight in late gestation. Singleton pregnancies were established using embryo transfer in 32 adolescent ewes, which were subsequently ove
Publikováno v:
Biology of Reproduction. 82:320-330
Nutritional backgrounds prior to pregnancy may interact with subsequent gestational intake to influence pregnancy outcome, particularly in young, growing adolescents. To investigate this interaction, singleton pregnancies were established in two grou