Investigating genetic and mechanistic interactors in familial cardoimyopathy through advanced disease modeling

Autor: Escribá Piera, Rubén

Publikováno v: TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
Fundación Tecnalia Research & Innovation
Dipòsit Digital de la UB
Universidad de Barcelona

[eng] Hypertrophic cardiomyopathy (HCM) is the most common inherited cardiac disease and a frequent cause of heart failure and sudden cardiac death. HCM is a highly complex condition defined by clinical and genetic heterogeneity. During last decades,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9afa7427129739b0be139d0ae5ccde21
http://hdl.handle.net/10803/674443

Development of an advanced 3D culture system for human cardiac tissue engineering

Autor: Valls Margarit, Maria

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
instname

[eng] Ischemic heart disease is a major cause of human death worldwide owing to the heart minimal ability to repair following injury. Other than heart transplantation, there are currently no effective or long-lasting therapies for end-stage heart fai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6c7a93f0f3e5fc3c64a3fa9e9ac0b77b
http://hdl.handle.net/2445/118888

Biotechnological approaches to cardiac differentiation of human induced pluripotent stem cells

Autor: Di Guglielmo, Claudia

Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
instname

[eng] The heart can be considered the most important organ of our body, as it supplies nutrients to all the cells. When affected from injuries or diseases, the heart function is hampered, as the damaged area is substituted by a fibrotic scar instead

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6dfa08118ce0bd50228c18d736a064d8
http://hdl.handle.net/10803/385921

Bioengineering approach to study the role of cell migration during zebrafish heart regneration

Autor: Tekeli, Işil

Publikováno v: TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
instname

Zebrafish heart regeneration remains one of the most interesting phenomena of the 21st century. Considering the extremely high rate of deaths due to cardiovascular diseases in the developed countries, 1 out of every 3 people, understanding natural ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::06011fbdb587798fa2106b82126e6658
http://hdl.handle.net/10803/396098

Molecular and cellular mechanisms of heart regeneration in zebrafish

Autor: Sleep Ronquillo, Eduard

Publikováno v: TDX (Tesis Doctorals en Xarxa)
TDR. Tesis Doctorales en Red
instname

In contrast to mammals, zebrafish do have the ability to regenerate their heart after injury. A better understanding of how regenerationcompetent species do so should help developing strategies to enhance human cardiac regeneration. Here, by genetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::51b1b67daa2ffe2eed97323b14ab7a4d
http://www.tdx.cat/TDX-0124111-085910