Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ray-Dean Pietersen"'
Autor:
Gina Leisching, Ray-Dean Pietersen, Vuyiseka Mpongoshe, Carel van Heerden, Paul van Helden, Ian Wiid, Bienyameen Baker
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153079 (2016)
During Mycobacterium tuberculosis (M.tb) infection, the initial interactions between the pathogen and the host cell determines internalization and innate immune response events. It is established that detergents such as Tween alter the mycobacterial
Externí odkaz:
https://doaj.org/article/0480dddccbfe45f3b5e1ceb9beec63a8
Autor:
Bienyameen Baker, Du Toit Loots, Ilse du Preez, Gina Leisching, Derylize Beukes, Ray-Dean Pietersen, Mari van Reenen
Publikováno v:
Journal of microbiological methods. 170
As a means to increase the growth rate and reduce aggregation, Tween 80 is routinely added to growth media during mycobacterial culturing. This detergent has, however, been associated with causing alterations to the morphology, pathogenicity and viru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7917272840ffcee93e4e7e97ee694d
https://pubmed.ncbi.nlm.nih.gov/31785333
https://pubmed.ncbi.nlm.nih.gov/31785333
Autor:
Gina Leisching, Carel J. van Heerden, Ray-Dean Pietersen, Bienyameen Baker, Ian Wiid, Paul D. van Helden
Publikováno v:
Virulence
The distinguishing factors that characterize the host response to infection with virulent Mycobacterium tuberculosis (M.tb) are largely confounding. We present an infection study with 2 genetically closely related M.tb strains that have vastly differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cf435685af1ad6f28bc70cf783c9ef3
https://doi.org/10.1080/21505594.2016.1250994
https://doi.org/10.1080/21505594.2016.1250994
Publikováno v:
Tuberculosis. 100:53-60
The culturing of mycobacteria is a standard procedure that is consistent world-wide, with little variation in the growth media constituents, particularly those found in liquid and solid media. Before the 1940s however, the aggregating nature of mycob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a02e8a9b403b148c2576fcea95a5d53
https://doi.org/10.1016/j.tube.2016.07.002
https://doi.org/10.1016/j.tube.2016.07.002
Autor:
Lyn-Marie Birkholtz, Johannes F. Wentzel, Andile H. Ngwane, Richard K. Haynes, David D. N'Da, Ho Ning Wong, Ray-Dean Pietersen, Bienyameen Baker, Ian Wiid, Mokhitli Morake, Dina Coertzen, Frans J. Smit
Publikováno v:
ChemMedChem. 13(1)
To evaluate the feasibility of developing drugs that may be active against both malaria and tuberculosis (TB) by using in part putative cholesterol transporters in the causative pathogens and through enhancement of passive diffusion in granulomatous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::608e73081de77d40db672b4cdee5bebf
https://pubmed.ncbi.nlm.nih.gov/29193799
https://pubmed.ncbi.nlm.nih.gov/29193799
Autor:
Ian Wiid, Robyn Roth, Heinrich C. Hoppe, Stoyan Stoychev, Christopher J. Parkinson, Ray-Dean Pietersen, A.K. Theron, C. P. Kenyon, C. W. van der Westhuyzen, Bienyameen Baker
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0185068 (2017)
PLoS ONE
PLoS ONE
Glutamine synthetase is a ubiquitous central enzyme in nitrogen metabolism that is controlled by up to four regulatory mechanisms, including adenylylation of some or all of the twelve subunits by adenylyl transferase. It is considered a potential the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f8b87a77b9fcb1f61c43224c1b29c51
http://europepmc.org/articles/PMC5626031?pdf=render
http://europepmc.org/articles/PMC5626031?pdf=render
Autor:
Albertus Viljoen, Monique J. Williams, Bienyameen Baker, Carine Sao Emani, Paul D. van Helden, Ian Wiid, Nicholas F. Hiten, Ray-Dean Pietersen
Publikováno v:
Antimicrobial Agents and Chemotherapy. 57:3202-3207
Ergothioneine (ERG) and mycothiol (MSH) are two low-molecular-weight thiols synthesized by mycobacteria. The role of MSH has been extensively investigated in mycobacteria; however, little is known about the role of ERG in mycobacterial physiology. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ce500fa1d263917c21fd27458d987bf
https://doi.org/10.1128/aac.02572-12
https://doi.org/10.1128/aac.02572-12
Autor:
Carel J. van Heerden, Gina Leisching, Vuyiseka Mpongoshe, Paul Van Helden, Ian Wiid, Ray-Dean Pietersen, Bienyameen Baker
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153079 (2016)
PLoS ONE
PLoS ONE
During Mycobacterium tuberculosis (M.tb) infection, the initial interactions between the pathogen and the host cell determines internalization and innate immune response events. It is established that detergents such as Tween alter the mycobacterial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8113fa5a93278c280ab6706be9e8fc1
http://europepmc.org/articles/PMC4824497?pdf=render
http://europepmc.org/articles/PMC4824497?pdf=render
Autor:
Lonji Kalombo, Bienyameen Baker, Yolandy Lemmer, Bathabile Ramalapa, Arwyn Tomos Jones, Hulda Swai, Jan A. Verschoor, Boitumelo Semete-Makokotlela, Ray-Dean Pietersen, Sandra Van Wyngaardt, Anton Stoltz, Chantal de Chastellier
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 211
The appearance of drug-resistant strains of Mycobacterium tuberculosis (Mtb) poses a great challenge to the development of novel treatment programmes to combat tuberculosis. Since innovative nanotechnologies might alleviate the limitations of current
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1abdf54106c0c3b48da0437a9c70623
https://pubmed.ncbi.nlm.nih.gov/26055640
https://pubmed.ncbi.nlm.nih.gov/26055640
Publikováno v:
European Journal of Cell Biology. 83:153-158
Summary The growth of pathogenic mycobacteria in phagosomes of the host cell correlates with their ability to prevent phagosome maturation. The underlying molecular mechanism remains elusive. In a previous study, we have shown that Mycobacterium aviu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc18eb068518c7afafb7d10f14d407a6
https://doi.org/10.1078/0171-9335-00370
https://doi.org/10.1078/0171-9335-00370