Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Ray W. Judy"'
Autor:
Ray W. Judy, Arlington A. Forist
Publikováno v:
Analytical Letters. 7:419-424
A spectrophotometric procedure for the determination of steroid oximes is described utilizing 11β-hydroxy-iia-methyl-5β-pregnane -3, 20 -dione dioxime (I) and iia-hydroxy-progesterone dioxime (II) as models. The method is based on (a) acid hydrolys
Publikováno v:
Journal of Medicinal Chemistry. 21:725-732
The metabolic fate of tolazamide, 1-(hexahydroazepin-1-yl)-3-p-tolylsulfonylurea (1), was studied in man and in the rat using tritium-labeled 1. The metabolites were isolated in crystalline form from urine for structure determination. The crystal str
Publikováno v:
Journal of Medicinal Chemistry. 14:969-971
Publikováno v:
The International journal of applied radiation and isotopes. 28(8)
The effective use of tritiated compounds in biological systems often requires determination of the extent to which the tritium label has been removed from the compound and equilibrated with biological fluids. (1) This usually is accomplished by first
Publikováno v:
Chemischer Informationsdienst. 9
The metabolic fate of tolazamide, 1-(hexahydroazepin-1-yl)-3-p-tolylsulfonylurea (1), was studied in man and in the rat using tritium-labeled 1. The metabolites were isolated in crystalline form from urine for structure determination. The crystal str
Publikováno v:
Journal of pharmaceutical sciences. 64(8)
Minoxidil (2,4-diamino-6-piperidinopyrimidine 3-oxide), a potent new hypotensive agent, was 14C-labeled in the 2-position of the pyrimidine ring in 17 percent yield from Ba14CO3. This material was used to study the absorption, distribution, and excre
Publikováno v:
Atherosclerosis. 29(1)
Colestipol hydrochloride, a polymeric, ion-exchange type, hypocholesterolemic agent, acting by sequestering bile acids, was labeled with carbon-14. The disposition of the labeled material was studied in the human, dog and rat. The extent of absorptio
Autor:
Ray W. Judy, Richard C. Thomas
Publikováno v:
Journal of medicinal chemistry. 15(9)
Publikováno v:
Analytical biochemistry. 13(2)
Autor:
Arlington A. Forist, Ray W. Judy
Publikováno v:
Journal of pharmaceutical sciences. 60(11)
Serum drug levels following oral administration of large single doses of chlorphenesin carbamate and methocarbamol were fitted to a one-compartment open model. The appearance of each drug was described by a short lag time followed by a rapid first-or