Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Ray R. Zhang"'
Autor:
Gopal Iyer, Reinier Hernandez, Jonathan W. Engle, Ariana N. Bitton, Jamey P. Weichert, Eduardo Aluicio-Sarduy, Ravi Patel, Anatoly Pinchuk, Joseph Grudzinski, Christopher Massey, Ray R. Zhang, Aakarsha V. Rao
Publikováno v:
Journal of Nuclear Medicine
There is a clinically unmet need for effective treatments for triple-negative breast cancer (TNBC), as it remains the most aggressive subtype of breast cancer. Herein, we demonstrate a promising strategy using a tumor-targeting alkylphosphocholine (N
Autor:
Joseph J. Grudzinksi, Ronald R. Burnette, Reinier Hernandez, John S. Kuo, Anatoly Pinchuk, Ray R. Zhang, Tej I Mehta, Paul A. Clark, Justin Jeffrey, Marc Longino, Jonathan A. Lubin, Jamey P. Weichert
Publikováno v:
Molecular Pharmaceutics. 16:3350-3360
Alkylphosphocholine (APC) analogs are a novel class of broad-spectrum tumor-targeting agents that can be used for both diagnosis and treatment of cancer. The potential for clinical translation for APC analogs will strongly depend on their pharmacokin
Autor:
Bruce Richard, Shahriar Salamat, Eduard Matkovic, John H. Fournelle, Ray R. Zhang, Howard A. Rowley
Publikováno v:
Acta Neuropathol
Autor:
Jamey P. Weichert, John S. Kuo, Alexandra B. Schroeder, Kevin W. Eliceiri, Eben L. Rosenthal, Jason M. Warram, Anatoly Pinchuk, Joseph Grudzinski, Ray R. Zhang
Publikováno v:
Nature Reviews Clinical Oncology. 14:347-364
Over the past two decades, synergistic innovations in imaging technology have resulted in a revolution in which a range of biomedical applications are now benefiting from fluorescence imaging. Specifically, advances in fluorophore chemistry and imagi
Autor:
Tongcheng Qian, Sean P. Palecek, Ray R. Zhang, Eric V. Shusta, Paul A. Clark, Abraham Al-Ahmad, Hannah K. Wilson, John S. Kuo, Jamey P. Weichert
Publikováno v:
Molecular Pharmaceutics. 13:3341-3349
Cancer-targeting alkylphosphocholine (APC) analogues are being clinically developed for diagnostic imaging, intraoperative visualization, and therapeutic applications. These APC analogues derived from chemically synthesized phospholipid ethers were i
Publikováno v:
Neurosurgery. 81:N34-N36
Publikováno v:
Neurosurgery. 83(3)
Autor:
Geoffrey G, Zhang, Lichung, Ku, Hsiang-Hsuan, Michael Yu, Siriporn, Sarangkasiri, Ray R, Zhang, Weiqi, Li, Vladimir, Feygelman
Publikováno v:
Journal of radiosurgery and SBRT. 1(3)
Forward-planned conformal arcs (termed dynamic arcs in the BrainLab iPlan system) have been routinely used in cranial stereotactic radiosurgery (SRS) for many yeras. This study compares dosimetric parameters of the newer, inversely-planned volumetric
Publikováno v:
Journal of Neuro-Oncology. 126:27-36
Diffuse Intrinsic Pontine Glioma (DIPG) is an aggressive pediatric brain tumor with a median survival of one year after diagnosis. It has been reported recently that about 80% of DIPG cases and 70% of midline glioblastomas contain a mutation at one a
Autor:
Kyle I. Swanson, Jamey P. Weichert, Mohammed Farhoud, Ray R. Zhang, Irawati Kandela, John S. Kuo, Paul A. Clark
Publikováno v:
Neurosurgery. 76:115-124
BACKGROUND 5-Aminolevulinic acid (5-ALA)-induced tumor fluorescence aids brain tumor resections but is not approved for routine use in the United States. We developed and describe testing of 2 novel fluorescent, cancer-selective alkylphosphocholine a