Zobrazeno 1 - 10
of 216
pro vyhledávání: '"Ray O Bahado-Singh"'
Autor:
Ray O Bahado-Singh, Sangeetha Vishweswaraiah, Buket Aydas, Ali Yilmaz, Raghu P Metpally, David J Carey, Richard C Crist, Wade H Berrettini, George D Wilson, Khalid Imam, Michael Maddens, Halil Bisgin, Stewart F Graham, Uppala Radhakrishna
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248375 (2021)
We evaluated the utility of leucocyte epigenomic-biomarkers for Alzheimer's Disease (AD) detection and elucidates its molecular pathogeneses. Genome-wide DNA methylation analysis was performed using the Infinium MethylationEPIC BeadChip array in 24 l
Externí odkaz:
https://doaj.org/article/d9537ca420cb4d748465ee176c2f4948
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0253340 (2021)
Autism spectrum disorder (ASD) is associated with abnormal brain development during fetal life. Overall, increasing evidence indicates an important role of epigenetic dysfunction in ASD. The placenta is critical to and produces neurotransmitters that
Externí odkaz:
https://doaj.org/article/5664f392ed594656b803784aa3ab2aa2
Autor:
Uppala Radhakrishna, Samet Albayrak, Rita Zafra, Alosh Baraa, Sangeetha Vishweswaraiah, Avinash M Veerappa, Deepthi Mahishi, Nazia Saiyed, Nitish K Mishra, Chittibabu Guda, Rouba Ali-Fehmi, Ray O Bahado-Singh
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0200229 (2019)
Ventricular Septal Defect (VSD), the most common congenital heart defect, is characterized by a hole in the septum between the right and left ventricles. The pathogenesis of VSD is unknown in most clinical cases. There is a paucity of data relevant t
Externí odkaz:
https://doaj.org/article/7c4ef876ecad48a2894b5d2a4a5b7d6f
Autor:
Uppala Radhakrishna, Samet Albayrak, Zeynep Alpay-Savasan, Amna Zeb, Onur Turkoglu, Paul Sobolewski, Ray O Bahado-Singh
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0154010 (2016)
Congenital heart defect (CHD) is the most common cause of death from congenital anomaly. Among several candidate epigenetic mechanisms, DNA methylation may play an important role in the etiology of CHDs. We conducted a genome-wide DNA methylation ana
Externí odkaz:
https://doaj.org/article/67c2daa9471b40faad9fc36ad35612f1
Autor:
Uppala Radhakrishna, Rupa Radhakrishnan, Lavanya V. Uppala, Srinivas B. Muvvala, Jignesh Prajapati, Rakesh M. Rawal, Ray O. Bahado-Singh, Senthilkumar Sadhasivam
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
BackgroundNeonatal Opioid Withdrawal Syndrome (NOWS) is a consequence of in-utero exposure to prenatal maternal opioids, resulting in the manifestation of symptoms like irritability, feeding problems, tremors, and withdrawal signs. Opioid use disorde
Externí odkaz:
https://doaj.org/article/0d6254b7eb4640eb8e65161d5031121a
Autor:
Ali Yilmaz, Sigal Liraz-Zaltsman, Esther Shohami, Juozas Gordevičius, Ieva Kerševičiūtė, Eric Sherman, Ray O. Bahado-Singh, Stewart F. Graham
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Traumatic brain injury (TBI) is a major cause of mortality and disability worldwide, particularly among individuals under the age of 45. It is a complex, and heterogeneous disease with a multifaceted pathophysiology that remains to be elucid
Externí odkaz:
https://doaj.org/article/52d7fe0c878a4d2bb6bc9d5e85acf5e4
Autor:
Onur Turkoglu, Ayse Citil, Ceren Katar, Ismail Mert, Robert A. Quinn, Ray O. Bahado-Singh, Stewart F. Graham
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10333 (2024)
Ectopic pregnancy (EP) is the leading cause of maternal morbidity and mortality in the first trimester. Using an untargeted metabolomic approach, we sought to identify putative plasma biomarkers using tandem liquid chromatography–mass spectrometry
Externí odkaz:
https://doaj.org/article/b5ae0218c9bd4cb597c7c34697fbade5
Autor:
Uppala Radhakrishna, Senthilkumar Sadhasivam, Rupa Radhakrishnan, Ariadna Forray, Srinivas B. Muvvala, Raghu P. Metpally, Saumya Patel, Rakesh M. Rawal, Sangeetha Vishweswaraiah, Ray O. Bahado-Singh, Swapan K. Nath
Publikováno v:
Frontiers in Genetics, Vol 14 (2024)
Background: Neonatal opioid withdrawal syndrome (NOWS), arises due to increased opioid use during pregnancy. Cytochrome P450 (CYP) enzymes play a pivotal role in metabolizing a wide range of substances in the human body, including opioids, other drug
Externí odkaz:
https://doaj.org/article/4dbab8a847cb42749fcafff78c1a1426
Autor:
Onur Turkoglu, Ali Alhousseini, Sonia Sajja, Jay Idler, Sean Stuart, Nadia Ashrafi, Ali Yilmaz, Kurt Wharton, Stewart F. Graham, Ray O. Bahado-Singh
Publikováno v:
Metabolomics. 19
Introduction: The impact of maternal coronavirus disease 2019 (COVID-19) infection on fetal health remains to be precisely characterized.Objectives: Using metabolomic profiling of newborn umbilical cord blood, we aimed to investigate the potential fe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a4bf35d6d4dd5632f4855ddf2e8890b
https://doi.org/10.1007/s11306-023-01988-x
https://doi.org/10.1007/s11306-023-01988-x
Autor:
Ali Yilmaz, Zafer Ugur, Ilyas Ustun, Sumeyya Akyol, Ray O. Bahado-Singh, Michael Maddens, Jan O. Aasly, Stewart F. Graham
Publikováno v:
Cells, Vol 9, Iss 11, p 2394 (2020)
CSF from unique groups of Parkinson’s disease (PD) patients was biochemically profiled to identify previously unreported metabolic pathways linked to PD pathogenesis, and novel biochemical biomarkers of the disease were characterized. Utilizing bot
Externí odkaz:
https://doaj.org/article/271de77f580c4175a68e23da7922feda