Zobrazeno 1 - 10
of 2 553
pro vyhledávání: '"Ray O"'
Autor:
Uppala Radhakrishna, Rupa Radhakrishnan, Lavanya V. Uppala, Srinivas B. Muvvala, Jignesh Prajapati, Rakesh M. Rawal, Ray O. Bahado-Singh, Senthilkumar Sadhasivam
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
BackgroundNeonatal Opioid Withdrawal Syndrome (NOWS) is a consequence of in-utero exposure to prenatal maternal opioids, resulting in the manifestation of symptoms like irritability, feeding problems, tremors, and withdrawal signs. Opioid use disorde
Externí odkaz:
https://doaj.org/article/0d6254b7eb4640eb8e65161d5031121a
Autor:
Ali Yilmaz, Sigal Liraz-Zaltsman, Esther Shohami, Juozas Gordevičius, Ieva Kerševičiūtė, Eric Sherman, Ray O. Bahado-Singh, Stewart F. Graham
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Traumatic brain injury (TBI) is a major cause of mortality and disability worldwide, particularly among individuals under the age of 45. It is a complex, and heterogeneous disease with a multifaceted pathophysiology that remains to be elucid
Externí odkaz:
https://doaj.org/article/52d7fe0c878a4d2bb6bc9d5e85acf5e4
Autor:
Onur Turkoglu, Ayse Citil, Ceren Katar, Ismail Mert, Robert A. Quinn, Ray O. Bahado-Singh, Stewart F. Graham
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10333 (2024)
Ectopic pregnancy (EP) is the leading cause of maternal morbidity and mortality in the first trimester. Using an untargeted metabolomic approach, we sought to identify putative plasma biomarkers using tandem liquid chromatography–mass spectrometry
Externí odkaz:
https://doaj.org/article/b5ae0218c9bd4cb597c7c34697fbade5
Publikováno v:
Cancer Medicine, Vol 12, Iss 19, Pp 19644-19655 (2023)
Abstract Background Pancreatic cancer (PC) is among the most lethal cancers. The lack of effective tools for early detection results in late tumor detection and, consequently, high mortality rate. Precision oncology aims to develop targeted individua
Externí odkaz:
https://doaj.org/article/cce1f63bf4134a7ebff1e6f9e5c7e6dd
Autor:
Uppala Radhakrishna, Senthilkumar Sadhasivam, Rupa Radhakrishnan, Ariadna Forray, Srinivas B. Muvvala, Raghu P. Metpally, Saumya Patel, Rakesh M. Rawal, Sangeetha Vishweswaraiah, Ray O. Bahado-Singh, Swapan K. Nath
Publikováno v:
Frontiers in Genetics, Vol 14 (2024)
Background: Neonatal opioid withdrawal syndrome (NOWS), arises due to increased opioid use during pregnancy. Cytochrome P450 (CYP) enzymes play a pivotal role in metabolizing a wide range of substances in the human body, including opioids, other drug
Externí odkaz:
https://doaj.org/article/4dbab8a847cb42749fcafff78c1a1426
Autor:
Ray O. Bahado-Singh, Amin Ibrahim, Zaid Al-Wahab, Buket Aydas, Uppala Radhakrishna, Ali Yilmaz, Sangeetha Vishweswaraiah
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Ovarian cancer (OC) is the most lethal gynecologic cancer due primarily to its asymptomatic nature and late stage at diagnosis. The development of non-invasive markers is an urgent priority. We report the accurate detection of epithelial OC
Externí odkaz:
https://doaj.org/article/bb696cacbf2445b293e29499c0c4fa77
Autor:
Uppala Radhakrishna, Swapan K. Nath, Lavanya V. Uppala, Avinash Veerappa, Ariadna Forray, Srinivas B. Muvvala, Raghu P. Metpally, Richard C. Crist, Wade H. Berrettini, Lori M. Mausi, Sangeetha Vishweswaraiah, Ray O. Bahado-Singh
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Introduction: The neonate exposed to opioids in utero faces a constellation of withdrawal symptoms postpartum commonly called neonatal opioid withdrawal syndrome (NOWS). The incidence of NOWS has increased in recent years due to the opioid epidemic.
Externí odkaz:
https://doaj.org/article/c43b82db4858456499c464d1dcf8d5a9
Autor:
Ray O. Bahado-Singh, Sangeetha Vishweswaraiah, Onur Turkoglu, Stewart F. Graham, Uppala Radhakrishna
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2876 (2023)
Precision neurology combines high-throughput technologies and statistical modeling to identify novel disease pathways and predictive biomarkers in Alzheimer’s disease (AD). Brain cytochrome P450 (CYP) genes are major regulators of cholesterol, sex
Externí odkaz:
https://doaj.org/article/570e4154e45c4946b3af860ebff1f981
Autor:
Ray O Bahado-Singh, Sangeetha Vishweswaraiah, Buket Aydas, Ali Yilmaz, Raghu P Metpally, David J Carey, Richard C Crist, Wade H Berrettini, George D Wilson, Khalid Imam, Michael Maddens, Halil Bisgin, Stewart F Graham, Uppala Radhakrishna
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0248375 (2021)
We evaluated the utility of leucocyte epigenomic-biomarkers for Alzheimer's Disease (AD) detection and elucidates its molecular pathogeneses. Genome-wide DNA methylation analysis was performed using the Infinium MethylationEPIC BeadChip array in 24 l
Externí odkaz:
https://doaj.org/article/d9537ca420cb4d748465ee176c2f4948
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0253340 (2021)
Autism spectrum disorder (ASD) is associated with abnormal brain development during fetal life. Overall, increasing evidence indicates an important role of epigenetic dysfunction in ASD. The placenta is critical to and produces neurotransmitters that
Externí odkaz:
https://doaj.org/article/5664f392ed594656b803784aa3ab2aa2