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Disentangling the genetic underpinnings of neuropsychiatric symptoms in Alzheimer's disease in the Alzheimer's Disease Sequencing Project: Study design and methodology.

Autor: Ray NR; Gertrude H. Sergievsky Center Columbia University New York New York USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain Columbia University New York New York USA., Kumar A; Gertrude H. Sergievsky Center Columbia University New York New York USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain Columbia University New York New York USA., Zaman A; The John P. Hussman Institute for Human Genomics University of Miami Miami Florida USA.; Dr. John T. MacDonald Foundation Department of Human Genetics University of Miami Miami Florida USA., Del Rosario P; Gertrude H. Sergievsky Center Columbia University New York New York USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain Columbia University New York New York USA., Mena PR; The John P. Hussman Institute for Human Genomics University of Miami Miami Florida USA.; Dr. John T. MacDonald Foundation Department of Human Genetics University of Miami Miami Florida USA., Manoochehri M; Department of Psychiatry and Human Behavior Alpert Medical School of Brown University Providence Rhode Island USA., Stein C; Department of Psychiatry and Human Behavior Alpert Medical School of Brown University Providence Rhode Island USA., De Vito AN; Department of Psychiatry and Human Behavior Alpert Medical School of Brown University Providence Rhode Island USA., Sweet RA; Department of Psychiatry School of Medicine University of Pittsburgh Pittsburgh Pennsylvania USA.; Department of Neurology School of Medicine University of Pittsburgh Pittsburgh Pennsylvania USA., Hohman TJ; Vanderbilt Memory and Alzheimer's Center Vanderbilt University Medical Center Nashville Tennessee USA.; Department of Neurology Vanderbilt University Medical Center Nashville Tennessee USA.; Vanderbilt Genetics Institute Vanderbilt University Medical Center Nashville Tennessee USA., Cuccaro ML; The John P. Hussman Institute for Human Genomics University of Miami Miami Florida USA.; Dr. John T. MacDonald Foundation Department of Human Genetics University of Miami Miami Florida USA., Beecham GW; The John P. Hussman Institute for Human Genomics University of Miami Miami Florida USA.; Dr. John T. MacDonald Foundation Department of Human Genetics University of Miami Miami Florida USA., Huey ED; Department of Psychiatry and Human Behavior Alpert Medical School of Brown University Providence Rhode Island USA., Reitz C; Gertrude H. Sergievsky Center Columbia University New York New York USA.; Taub Institute for Research on Alzheimer's Disease and the Aging Brain Columbia University New York New York USA.; Department of Neurology Columbia University New York New York USA.; Department of Epidemiology Columbia University New York New York USA.

Publikováno v: Alzheimer's & dementia (Amsterdam, Netherlands) [Alzheimers Dement (Amst)] 2024 Aug 23; Vol. 16 (3), pp. e70000. Date of Electronic Publication: 2024 Aug 23 (Print Publication: 2024).

Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry.

Autor: Ray NR; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA., Kunkle BW; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA., Hamilton-Nelson K; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA., Kurup JT; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA., Rajabli F; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA., Qiao M; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA., Vardarajan BN; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA., Cosacak MI; German Center for Neurodegenerative Diseases, Dresden, Germany., Kizil C; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA., Jean-Francois M; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA., Cuccaro M; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA., Reyes-Dumeyer D; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA., Cantwell L; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Kuzma A; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Vance JM; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA., Gao S; Department of Biostatistics and Health Data Science, Indiana University School of Medicine, Indianapolis, Indiana, USA., Hendrie HC; Department of Psychiatry, Indiana University School of Medicine, Indianapolis, Indiana, USA., Baiyewu O; College of Medicine, University of Ibadan, Ibadan, Oyo, Nigeria., Ogunniyi A; College of Medicine, University of Ibadan, Ibadan, Oyo, Nigeria., Akinyemi RO; College of Medicine, University of Ibadan, Ibadan, Oyo, Nigeria., Lee WP; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Martin ER; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA.; Dr. John T. MacDonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, USA., Wang LS; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Beecham GW; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA., Bush WS; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Biomedical Research, Cleveland, Ohio, USA.; Department of Population and Quantitative Health Sciences and Cleveland Institute for Computational Biology, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA., Xu W; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Biomedical Research, Cleveland, Ohio, USA., Jin F; Department of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Biomedical Research, Cleveland, Ohio, USA.; Department of Population and Quantitative Health Sciences and Cleveland Institute for Computational Biology, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA., Wang L; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA., Farrer LA; Department of Medicine, Biomedical Genetics Section, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA.; Department of Ophthalmology, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA., Haines JL; Department of Population and Quantitative Health Sciences and Cleveland Institute for Computational Biology, School of Medicine, Case Western Reserve University, Cleveland, Ohio, USA., Byrd GS; Maya Angelou Center for Health Equity, Wake Forest School of Medicine, Winston-Salem, North Carolina, USA., Schellenberg GD; Penn Neurodegeneration Genomics Center, Department of Pathology and Laboratory Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA., Mayeux R; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA.; Department of Neurology, Columbia University, New York, New York, USA.; Department of Psychiatry, Columbia University, New York, New York, USA.; Epidemiology, College of Physicians and Surgeons, Columbia University, New York, New York, USA., Pericak-Vance MA; The John P. Hussman Institute for Human Genomics, University of Miami, Miami, Florida, USA.; Dr. John T. MacDonald Foundation Department of Human Genetics, University of Miami, Miami, Florida, USA., Reitz C; Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, New York, USA.; Gertrude H. Sergievsky Center, Columbia University, New York, New York, USA.; Department of Neurology, Columbia University, New York, New York, USA.; Epidemiology, College of Physicians and Surgeons, Columbia University, New York, New York, USA.

Publikováno v: Alzheimer's & dementia : the journal of the Alzheimer's Association [Alzheimers Dement] 2024 Aug; Vol. 20 (8), pp. 5247-5261. Date of Electronic Publication: 2024 Jul 03.