Zobrazeno 1 - 10
of 198
pro vyhledávání: '"Ray McDermott"'
Autor:
Tom Venken, Ian S. Miller, Ingrid Arijs, Valentina Thomas, Ana Barat, Johannes Betge, Tianzuo Zhan, Timo Gaiser, Matthias P. Ebert, Alice C. O’Farrell, Jochen Prehn, Rut Klinger, Darran P. O’Connor, Brian Moulton, Verena Murphy, Garazi Serna, Paolo G. Nuciforo, Ray McDermott, Brian Bird, Gregory Leonard, Liam Grogan, Anne Horgan, Nadine Schulte, Markus Moehler, Diether Lambrechts, Annette T. Byrne
Publikováno v:
npj Genomic Medicine, Vol 9, Iss 1, Pp 1-10 (2024)
Abstract To predict outcome to combination bevacizumab (BVZ) therapy, we employed cell-free DNA (cfDNA) to determine chromosomal instability (CIN), nucleosome footprints (NF) and methylation profiles in metastatic colorectal cancer (mCRC) patients. L
Externí odkaz:
https://doaj.org/article/7492becf8fc3468584cbff1ca25b4e7f
Autor:
Sampsa Kinos, Helga Hagman, Päivi Halonen, Leena-Maija Soveri, Mary O'Reilly, Per Pfeiffer, Jan-Erik Frödin, Halfdan Sorbye, Eetu Heervä, Gabor Liposits, Raija Kallio, Annika Ålgars, Raija Ristamäki, Tapio Salminen, Maarit Bärlund, Carl-Henrik Shah, Ray McDermott, Rebecka Röckert, Petra Flygare, Johannes Kwakman, Arco Teske, Cornelis Punt, Bengt Glimelius, Pia Österlund
Publikováno v:
Acta Oncologica, Vol 63, Iss 1 (2024)
Background and purpose: The CardioSwitch-study demonstrated that patients with solid tumors who develop cardiotoxicity on capecitabine or 5-fluorouracil (5-FU) treatment can be safely switched to S-1, an alternative fluoropyrimidine (FP). In light of
Externí odkaz:
https://doaj.org/article/340dd2f28c5441ddaf0adaf8e0022afa
Autor:
Guillaume Grisay, Fabio Turco, Saskia Litiere, Béatrice Fournier, Anna Patrikidou, Enrique Gallardo, Ray McDermott, Ahu Alanya, Silke Gillessen, Bertrand Tombal
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
The landscape of treating metastatic prostate cancer has evolved with the addition of Androgen Receptor pathway inhibitor (ARPI) to Androgen Deprivation Therapy (ADT), significantly improving survival rates. However, prolonged use of these therapies
Externí odkaz:
https://doaj.org/article/81835467e73e4364af4a30938a8d05b9
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Targeting the RAS pathway remains the holy grail of precision oncology. In the case of pancreatic ductal adenocarcinomas (PDAC), 90–92% harbor mutations in the oncogene KRAS, triggering canonical MAPK signaling. The smooth structure of the altered
Externí odkaz:
https://doaj.org/article/df90e00437fb426884e59d706b84c124
Autor:
Mary O’Reilly, Aleksandar Krstic, Luis F. Iglesias-Martinez, Éanna J. Ryan, Bruce Moran, Des Winter, Kieran Sheahan, Ray McDermott, Walter Kolch
Publikováno v:
Journal of Personalized Medicine, Vol 14, Iss 6, p 639 (2024)
Early-onset colorectal cancer (EOCRC), defined as colorectal cancer in individuals under 50 years of age, has shown an alarming increase in incidence worldwide. We report a case of a twenty-four-year-old female with a strong family history of colorec
Externí odkaz:
https://doaj.org/article/a3ef6a494cbc45ac8d1769223a2f6c7a
Autor:
Gillian Murtagh, James L. Januzzi, Marielle Scherrer‐Crosbie, Tomas G. Neilan, Susan Dent, Jennifer E. Ho, Vinesh Appadurai, Ray McDermott, Nausheen Akhter
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 12, Iss 21 (2023)
ABSTRACT Cardiotoxicity is a growing concern in the oncology population. Transthoracic echocardiography and multigated acquisition scans have been used for surveillance but are relatively insensitive and resource intensive. Innovative imaging techniq
Externí odkaz:
https://doaj.org/article/fff5d80966a54a05b23e19381cc66a9c
Autor:
Lorelei A. Mucci, Jacob Vinson, Theresa Gold, Travis Gerke, Julie Filipenko, Rebecca M. Green, Simon G. Anderson, Simone Badal, Anders Bjartell, Kim N. Chi, Ian D. Davis, Deborah Enting, André P. Fay, John Lazarus, Joaquin Mateo, Ray McDermott, Folakemi T. Odedina, David Olmos, Aurelius Omlin, Ademola A. Popoola, Camille Ragin, Robin Roberts, Kjell M. Russnes, Charles Waihenya, Konrad H. Stopsack, Terry Hyslop, Paul Villanti, Philip W. Kantoff, Daniel J. George
Publikováno v:
JCO Global Oncology, Vol , Iss 8 (2022)
PURPOSETo describe a newly established international registry recruiting diverse patients with advanced prostate cancer across academic and community practices to address unmet needs in this population.PATIENTS AND METHODSInitiated in 2017, IRONMAN (
Externí odkaz:
https://doaj.org/article/c2ac1375880a4f8296dca71b57375939
Autor:
Fiona O’Neill, Taylor-Jade Allen-Coyle, Sandra Roche, Justine Meiller, Neil T. Conlon, Niall Swan, Robert M. Straubinger, Justin Geoghegan, Ninfa L. Straubinger, Kevin Conlon, Ray McDermott, Finbarr O’Sullivan, Michael Henry, Paula Meleady, Gerard McVey, Robert O’Connor, Michael Moriarty, Martin Clynes
Publikováno v:
Life, Vol 13, Iss 3, p 608 (2023)
Herein, we describe the global comparison of miRNAs in human pancreatic cancer tumors, adjacent normal tissue, and matched patient-derived xenograft models using microarray screening. RNA was extracted from seven tumor, five adjacent normal, and eigh
Externí odkaz:
https://doaj.org/article/a7c66f94d63d447e9e0fc09d6ba50f6e
Publikováno v:
Cancers, Vol 14, Iss 19, p 4751 (2022)
Since 2010, significant progress has been made in the treatment of metastatic castrate resistant prostate cancer (mCRPC). While these advancements have improved survival, mCRPC remains a lethal disease, with a precision medicine framework that is lag
Externí odkaz:
https://doaj.org/article/5ba6d73cd9a44009b985e662fc4608e9
Autor:
Gregory S Mellotte, Diya Sabu, Mary O’Reilly, Ray McDermott, Anthony O’Connor, Barbara M Ryan
Publikováno v:
Melanoma Management, Vol 7, Iss 4 (2020)
Aim: Primary gastric melanoma is a rare clinical presentation. The purpose of this review was to compare the 1-year survival in patients who underwent surgery with patients who did not receive treatment. Patients & methods: A systematic search of dat
Externí odkaz:
https://doaj.org/article/27f73785f3b2463d8b55a559ab766afe