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Akademický článek

Short Report: Lack of Diurnal Variation in Salivary Cortisol Is Linked to Sleep Disturbances and Heightened Anxiety in Adolescents with Williams Syndrome

Autor: Jessica Hayton, Atiqah Azhari, Gianluca Esposito, Ray Iles, Michaella Chadiarakos, Giulio Gabrieli, Dagmara Dimitriou, Stephen Mangar

Publikováno v: Behavioral Sciences, Vol 13, Iss 3, p 220 (2023)

Objective: The aim of the current study was to examine the potential relationship between sleep patterns, cortisol levels, and anxiety profiles in adolescents with Williams Syndrome (WS) compared to typically developing adolescents. Method: Thirteen

Externí odkaz: https://doaj.org/article/cb25d8be33ee475191eaa659a72201a6

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Akademický článek

Regulation of human chorionic gonadotropin beta subunit expression in ovarian cancer

Autor: Aleksandra Śliwa, Marta Kubiczak, Anna Szczerba, Grzegorz Walkowiak, Ewa Nowak-Markwitz, Beata Burczyńska, Stephen Butler, Ray Iles, Piotr Białas, Anna Jankowska

Publikováno v: BMC Cancer, Vol 19, Iss 1, Pp 1-9 (2019)

Abstract Purpose Expression of human chorionic gonadotropin beta subunit by cancers is extensively documented, yet regulation of the multiple genes that can code for this protein is poorly understood. The aim of the study was to examine the mechanism

Externí odkaz: https://doaj.org/article/ee8578e1a6ce4d4096d295e4a513316e

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Akademický článek

The Diagnosis of Sulfated Hemoglobin (SulfHb) Secondary to Sulfur Dioxide Poisoning Using Matrix-Assisted Laser Desorption Time-of-Flight Mass Spectrometry (MALDI-ToF MS)—A Novel Approach to an Unusual Clinical Problem

Autor: Suzanne Docherty, Raminta Zmuidinaite, James Coulson, Martin Besser, Ray Iles

Publikováno v: Diagnostics, Vol 10, Iss 2, p 94 (2020)

Sulfhemoglobinemia is a rare entity caused by irreversible sulfation of the heme moiety in haemoglobin to form sulfated haemoglobin (SulfHb) and has been caused by H2S arising from certain metabolites of drugs and bacterial infection. Clinical presen

Externí odkaz: https://doaj.org/article/4a30281e3f164fcca0998c56f9404dd4

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Akademický článek

Rapid, Affordable and Efficient Screening of Multiple Blood Abnormalities Made Possible Using an Automated Tool for MALDI-ToF Spectrometry Analysis

Autor: Ricardo J. Pais, Christian Jardine, Raminta Zmuidinaite, Jonathan Lacey, Steve Butler, Ray Iles

Publikováno v: Applied Sciences, Vol 9, Iss 23, p 4999 (2019)

Screening programs for genetic and metabolic diseases such as haemoglobinopathies, thalassemias and diabetes are a worldwide problem that faces economic and technological limitations. This is mainly because genetic and metabolic tests are too expensi

Externí odkaz: https://doaj.org/article/ee47b34dd64f498fa8da7619db7f5c6c

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The 2021 NICE guidelines for assessment and management of chronic pain: A cross-sectional study mapping against a sample of 1,000* in the community

Autor: Zoe Zambelli, Elizabeth J Halstead, Ray Iles, Antonio R Fidalgo, Dagmara Dimitriou

Publikováno v: British Journal of Pain. 16:439-449

Objectives To characterise the prevailing pharmacological and non-pharmacological pain management strategies among adults with chronic pain, comparing these against the newly published NICE guidelines NG-193, and examine these pre-NG-193 pain managem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59a927af8078e43630f8f3846398ba03
https://doi.org/10.1177/20494637221083837

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The COVID-19 antibody responses, isotypes and glycosylation: Why SARS-CoV-2 Spike protein complex binding of IgG3 is potentiated in some and immuno-pathologies manifest

Autor: Ray Iles

COVID-19 syndrome does not occur in all who are infected with SARS-CoV-2, and symptoms vary. The anti-SARS CoV-2 Spike immune responses is confounded by the Spike proteins ability to bind Igγ3 heavy chains. This appears to be via sialic acid glycans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6f5262261c79c031c743324249a0762f
https://doi.org/10.1101/2023.01.13.23284524

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Substantial urinary concentrations of material resembling beta-core fragment of chorionic gonadotropin beta-subunit in mid-menstrual cycle

Autor: Chard T, Wp, Collins, Edwards R, Howes I, Ray Iles, Neven P, Sharma K, Jh, Shepherd

Publikováno v: Europe PubMed Central

We measured the day-to-day variations in concentrations of beta-core, luteinizing hormone (LH), and alpha-subunit in urine during the menstrual cycle. The alpha-subunit concentrations showed a pattern similar to that of the LH concentrations. beta-Co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::394892737298191af6edfa3c2fae74bb
https://pubmed.ncbi.nlm.nih.gov/8375060

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