Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ray G. Goodwin"'
Publikováno v:
Blood. 98:3058-3065
Tumor necrosis factor–related apoptosis-inducing ligand (TRAIL), a member of the tumor necrosis factor (TNF) family, binds to several cell-surface receptors with distinct functions (agonistic receptors 1 and 2 [TRAIL-R1, TRAIL-R2]; decoy receptors
Autor:
Lisa M. Sedger, Donna M. Shows, Rebecca A. Blanton, Jacques J. Peschon, Ray G. Goodwin, David Cosman, Steven R. Wiley
Publikováno v:
The Journal of Immunology. 163:920-926
TNF-related apoptosis-inducing ligand (TRAIL) is able to kill many transformed cells of diverse tissue types. We show that TRAIL is inducible by IFN-γ, by TNF-α, and by infection with human CMV, and has potent antiviral activity in vitro. CMV infec
Autor:
Kurt D. Shanebeck, Craig A. Smith, Ray G. Goodwin, Mary K. Kennedy, Kathleen S. Picha, Kenneth H. Grabstein, Charles R. Maliszewski
Publikováno v:
European Journal of Immunology. 25:2147-2153
A ligand for CD30 has been recently cloned, and has been shown to have sequence homology with the tumor necrosis factor family of cytokines. CD30 ligand (CD30L) was found to be induced on helper T cell clones, and its receptor was expressed on freshl
Publikováno v:
Human Genetics. 89
A DNA probe for the interleukin-7 receptor gene was used for in situ hybridisation and Southern blot analysis of a series of rodent-human hybrid cell lines. The IL-7 receptor gene maps to 5p13.
Autor:
JoAnn C. L. Schuh, Tiep Le, Brian Gliniak, Moira Glaccum, Suzanne T. Kanaly, Nobuhiko Kayagaki, Pam J. Smolak, Ray G. Goodwin, Lisa M. Sedger, Eilidh Williamson, Theordore Yun
Publikováno v:
European Journal of Immunology. 32:2246
To define the normal physiological role for the TRAIL/Apo2L in vivo, we generated TRAIL/Apo2L gene-targeted mice. These mice develop normally and show no defects in lymphoid or myeloid cell homeostasis or function. Although TRAIL/Apo2L kills transfor
Autor:
Sally A. Camper, Fritz M. Rottman, Dennis N. Luck, Robert H. Lyons, Ray G. Goodwin, Richard P. Woychik, Yvonne Yao
Publikováno v:
DNA. 3:237-249
The gene coding for bovine prolactin was shown to exist as a single copy per haploid genome. Three restriction fragment polymorphisms were detected in the prolactin gene by Southern blot analysis of DNA obtained from the semen of pedigreed bulls repr