Zobrazeno 1 - 10
of 126
pro vyhledávání: '"Ray D. Lloyd"'
Publikováno v:
Health Physics. 86:629-632
No significant differences in lifespan could be established between control dogs and dogs given 2 4 1 Am, 2 2 8 Th, 9 0 Sr, 2 2 8 Ra, 2 2 6 Ra or monomeric 2 3 9 Pu at low dosage levels that induced less than 10% skeletal malignancies (low dose anima
Publikováno v:
Health Physics. 86:42-55
A compartmental model of the distribution of radium in humans and young adult beagle dogs (approximately 500-550 d) is presented. The model consists of one soft tissue compartment and seven skeletal compartments for humans, and five skeletal compartm
Autor:
Erich Polig, Ray D. Lloyd, Fred W. Bruenger, M. P. Krahenbuhl, Sergey A. Romanov, Scott C. Miller
Publikováno v:
Radiation Research. 160:517-523
Osteosarcomas occur from exposures to bone-seeking, alpha-particle-emitting isotopes, particularly plutonium. The skeletal distribution of putative 239Pu-induced osteosarcomas reported in Mayak Metallurgical and Radiochemical Plutonium Plant workers
Publikováno v:
Health Physics. 81:691-697
A long term biological study has been completed that was designed to assess the predicted effects in humans of internally deposited 239Pu by comparison with 226Ra in beagles. Herein we summarize for the first time results of several previous reports
Publikováno v:
Mathematical and Computer Modelling. 33:1377-1386
This paper considers the utility of a stochastic model of carcinogenesis, proposed earlier by Yakovlev and Polig, in quantitative analysis of the incidence of radiation-induced osteosarcomas in beagels injected with various amounts of ^2^3^9Pu. The o
Publikováno v:
Mathematical and Computer Modelling. 33:1315-1322
A three-stage model for the induction of bone tumors in beagles from single injections of ^2^3^9Pu is presented. The model involves branching with one or two initiation steps controlled by radiation. It was applied to six groups of animals with grade
Publikováno v:
Health Physics. 79:199-202
Investigation of a possible increase in sensitivity to occurrence of radionuclide-induced skeletal malignancy with increasing body size was analyzed among 358 beagles injected as young adults with either 226 Ra or monomeric 239 Pu and maintained for
Publikováno v:
Health Physics. 78:182-190
A biokinetic model of the systemic distribution and dosimetry of 239Pu in the beagle dog is presented. To achieve maximum consistency with experimental data, known histomorphometric parameters and results of autoradiographic studies were adopted dire
Publikováno v:
Health Physics. 75:640-645
Beagle dogs injected with 241Am and treated subsequently with DTPA exhibited a reduced occurrence of skeletal malignancies and increased lifespans when compared to corresponding untreated animals also given 241Am. Whereas 92% of dogs given about 11 k
Publikováno v:
Health Physics. 75:251-258
The microdistribution Of 239Pu was analyzed in the humerus, lumbar vertebra, and proximal ulna of young adult beagles using neutron induced autoradiography. The animals were sacrificed serially in groups of three at 4, 8, 16, 32, and 64 wk after a si