Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Ray Bendele"'
Autor:
Ray Bendele, John Desjardins, Susan Karimi, Beth Abbott, Frank C. Richardson, Dennis J. Meyer, Greg Biesecker
Publikováno v:
Antiviral Research. 58:217-225
The antiviral compound tenofovir DF (Gilead Sciences) was evaluated for possible mitochondrial toxicity in rats, rhesus monkeys and woodchucks. Animals were treated by oral gavage with tenofovir DF, and the levels of mitochondrial enzymes cytochrome
Publikováno v:
Toxicologic Pathology. 27:22-26
The following material was derived from a synthesis of case histories taken from investigational new drug (IND) applications and drug sponsors' experiences, utilizing fictionalized data to avoid any resemblance to any proprietary information; any suc
Autor:
Jeremy D. LeRay, Michelle Pelanne, Blake Tomkinson, Eric N. Brown, Karen Hart, David L. Emerson, Denny J. Meyer, Atherton G. Gray, Ray Bendele, Francis J. Giles
Publikováno v:
Leukemia research. 27(11)
OSI-211 (liposomal lurtotecan), was evaluated using several different dose schedules (1mg/kg, d1-5, 1.75 mg/kg d1, 3, 5 and 6 mg/kg d1, 8) in severe combined immunodeficient (SCID) mouse models of acute myelogenous leukemia (AML) and acute lymphocyti
Autor:
Koen K. A. Van Rompay, Ross P. Tarara, Wilhelm Von Morgenland, Marta L. Marthas, Abigail Spinner, John Desjardins, David R. Bennett, Valerie F. Samii, Christopher Jerome, Alesha B. Castillo, Norbert Bischofberger, Dennis J. Meyer, Trish G. Dearman, Marta Hamilton, Niels C Pedersen, Celia R. Valverde, Phil C. Allen, R. Bruce Martin, Don R. Canfield, Linda Hirst, Laurie L. Brignolo, Ray Bendele
Publikováno v:
Antimicrobial Agents and Chemotherapy. 48:2346-2346
The reverse transcriptase inhibitor 9-[2-(phosphonomethoxy)propyl]adenine (PMPA; tenofovir) was previously found to offer strong prophylactic and therapeutic benefits in an infant macaque model of pediatric human immunodeficiency virus (HIV) infectio