Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Ray A. James"'
Autor:
Picthall, Daniel1 (AUTHOR), Ray, Matthew James2 (AUTHOR), Slawin, Alexandra Martha Zoya1 (AUTHOR), Kilian, Petr1 (AUTHOR) pk7@st-andrews.ac.uk
Publikováno v:
Molbank. Dec2022, Vol. 2022 Issue 4, pM1523. 5p.
Akademický článek
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Autor:
Jocelyn Rivera, Xiaoying Xu, Haengsoon Park, Lesley Schultz, Kamil Paruch, David A. Parry, Alvarez Carmen S, Emma Lees, Thierry O. Fischmann, Doll Ronald J, Tara M. Stauffer, Laura R. Rokosz, Chad E. Knutson, Wolfgang Seghezzi, Vincent S. Madison, Alan Hruza, Michael P. Dwyer, Ray Anthony James, Derek Wiswell, Mckittrick Brian A, Greg Tucker, Frances Shanahan, Nicole Sgambellone, Kerry Keertikar, Randall R. Rossman, Timothy J. Guzi, Vidyadhar M. Paradkar, Yaolin Wang, Quiao Zhou, Paul Kirschmeier, Amin A. Nomeir, Tin-Yau Chan, Courtney Brown
Publikováno v:
ACS Medicinal Chemistry Letters. 1:204-208
Inhibition of cyclin-dependent kinases (CDKs) has emerged as an attractive strategy for the development of novel oncology therapeutics. Herein is described the utilization of an in vivo screening approach with integrated efficacy and tolerability par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b7390edd40f7ca65dc0aeccd13f3ca9
https://doi.org/10.1021/ml100051d
https://doi.org/10.1021/ml100051d
Autor:
Celia Kingsbury, Irina Neagu, Ming You, Haengsoon Park, Tsung H. Lin, Koc-Kan Ho, Elizabeth Quadros, Maria L. Webb, Michael Ohlmeyer, Yuefei Shao, Matthew Sills, Jeffrey J. Letourneau, Andrew G. Cole, Yingchun Lu, Earl F. Kimble, Jorge Quintero, Riviello Christopher, Ray Anthony James, Bojing Wang, Vidyadhar M. Paradkar, Adolph Bohnstedt, Kenneth C. Appell, David J. Diller
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:6788-6792
A novel class of Janus tyrosine kinase 3 (JAK3) inhibitors based on a 2-benzimidazoylpurinone core structure is described. Through substitution of the benzimidazoyl moiety and optimization of the N-9 substituent of the purinone, compound 24 was ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dd21d26420d59e8a1c379ce66894ef1
https://doi.org/10.1016/j.bmcl.2009.09.080
https://doi.org/10.1016/j.bmcl.2009.09.080
Publikováno v:
Tetrahedron. 53:8837-8852
We have demonstrated that 4-O-acetyl-6-bromo-3-O-(tert-butyldimethylsilyl)-2-deoxy-2-thiophenyl-1-trichloroacetimido-α- d -glucopyranose 11b is the most efficient and selective donor for use in the synthesis of 2-deoxy-β-glycosides of the series of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f757aacd88bb838dac0d8fd94c1b214
https://doi.org/10.1016/s0040-4020(97)90395-1
https://doi.org/10.1016/s0040-4020(97)90395-1
Autor:
Ray, Matthew James
The clean reaction of 5-lithio-6-diisopropylphosphinoacenaphthene (1') with dichlorophosphines, RPCl₂ (R = Ph, Fc, NMe₂, iPr), led to the formation of peri-substituted phosphino-phosphonium chloride salts 2-5. The synthetic utility of these salts
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______901::ec03ddd1e2314dd47fb7ad17c7b920ca
https://hdl.handle.net/10023/3866
https://hdl.handle.net/10023/3866
Publikováno v:
Journal of Structural Engineering. 120:81-99
This paper presents a decision-support system for selecting the best set of strategies (projects) for bridge rehabilitation and replacement on a highway network, specifically during a long-range planning of the bridge funding needs for budgeting and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b02acdc0988f82b75ef5fa7b9902d84
https://doi.org/10.1061/(asce)0733-9445(1994)120:1(81)
https://doi.org/10.1061/(asce)0733-9445(1994)120:1(81)
A STUDY OF THE INTERFACIAL REACTION KINETICS IN THE IRON - CALCIUM-FLUORIDE SYSTEM AT 1450 DEGREES C
Autor:
Ray, Douglas James
An understanding of the chemical reaction kinetics at a slag/metal interface requires knowledge of both transport and interfacial properties. However, fundamental interfacial reaction rate data are largely unavailable. Consequently, the ion exchange
Externí odkaz:
http://hdl.handle.net/11375/8210
Publikováno v:
ChemInform. 28
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e3632418a82c4193f6f5cc560fcdb6b
https://doi.org/10.1002/chin.199743240
https://doi.org/10.1002/chin.199743240
Autor:
Jinqi Liu, Maria L. Webb, Hema Desai, Vidyadhar M. Paradkar, Weiqing Chen, Linda M. O’Brien, Kenneth C. Appell, Elizabeth Quadros, J. Robert Merritt, Jennifer Postelnek, Camelia Chiriac, Chongwu Zhang, Michael Ohlmeyer, Nicole White, Earl F. Kimble, Ray Anthony James, Catherine M. Hicks, Pamela G. Wines, Ruiyan Liu, Biji Jacob
Publikováno v:
Bioorganicmedicinal chemistry letters. 20(18)
A novel series of pyrrolidine heterocycles was prepared and found to show potent inhibitory activity of CCR1 binding and CCL3 mediated chemotaxis of a CCR1-expressing cell line. A potent, optimized triazole lead from this series was found to have acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5aea68cdfb9c886862fba4f24a9c7db2
https://pubmed.ncbi.nlm.nih.gov/20708929
https://pubmed.ncbi.nlm.nih.gov/20708929