Zobrazeno 1 - 10
of 263
pro vyhledávání: '"Ray, DW."'
Publikováno v:
Frontiers in Immunology. 13
Vaccination, as a public health measure, offers effective protection of populations against infectious diseases. Optimising vaccination efficacy, particularly for higher-risk individuals, like the elderly whose immunocompromised state can prevent the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dbe6377741fb2bead90df290d9ccd23
https://doi.org/10.3389/fimmu.2022.977525
https://doi.org/10.3389/fimmu.2022.977525
Autor:
Baxter, M, Poolman, T, Cunningham, P, Hunter, L, Voronkov, M, Kitchen, GB, Goosey, L, Begley, N, Kay, D, Hespe, A, Maidstone, R, Loudon, ASI, Ray, DW
Publikováno v:
Baxter, M, Poolman, T, Cunningham, P, Hunter, L, Voronkov, M, Kitchen, G B, Goosey, L, Begley, N, Kay, D, Hespe, A, Maidstone, R, Loudon, A S I & Ray, D W 2022, ' Circadian clock function does not require the histone methyltransferase MLL3 ', The FASEB Journal, vol. 36, no. 7, e22356 . https://doi.org/10.1096/fj.202200368R
The circadian clock controls the physiological function of tissues through the regulation of thousands of genes in a cell-type-specific manner. The core cellular circadian clock is a transcription–translation negative feedback loop, which can recru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5807f1c356f77bae31836d5e297f896
https://doi.org/10.1096/fj.202200368r
https://doi.org/10.1096/fj.202200368r
Autor:
Caratti, G, Poolman, T, Hurst, RJ, Ince, L, Knight, A, Krakowiak, K, Durrington, HJ, Gibbs, J, Else, KJ, Matthews, LC, Ray, DW
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Caratti, G, Poolman, T, Hurst, R J, Ince, L, Knight, A, Krakowiak, K, Durrington, H J, Gibbs, J, Else, K J, Matthews, L C & Ray, D W 2019, ' Caveolin1 interacts with the glucocorticoid receptor in the lung but is dispensable for its anti-inflammatory actions in lung inflammation and Trichuris Muris infection ', Scientific Reports, vol. 9, no. 1, 8581 . https://doi.org/10.1038/s41598-019-44963-0
Caratti, G, Poolman, T, Hurst, R J, Ince, L, Knight, A, Krakowiak, K, Durrington, H J, Gibbs, J, Else, K J, Matthews, L C & Ray, D W 2019, ' Caveolin1 interacts with the glucocorticoid receptor in the lung but is dispensable for its anti-inflammatory actions in lung inflammation and Trichuris Muris infection ', Scientific Reports, vol. 9, no. 1, 8581 . https://doi.org/10.1038/s41598-019-44963-0
Glucocorticoids (Gcs) are widely prescribed anti-inflammatory compounds, which act through the glucocorticoid receptor (GR). Using an unbiased proteomics screen in lung tissue, we identified the membrane protein caveolin -1 (Cav1) as a direct interac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::06a786b7360bf7b731e2227018cb1a55
http://link.springer.com/article/10.1038/s41598-019-44963-0
http://link.springer.com/article/10.1038/s41598-019-44963-0
Autor:
Jones, SE, Lane, JM, Wood, AR, van Hees, VT, Tyrrell, J, Beaumont, RN, Jeffries, AR, Dashti, HS, Hillsdon, M, Ruth, KS, Tuke, MA, Yaghootkar, H, Sharp, SA, Jie, YJ, Thompson, WD, Harrison, JW, Dawes, A, Byrne, EM, Tiemeier, Henning, Allebrandt, KV, Bowden, J, Ray, DW, Freathy, RM, Murray, A, Mazzotti, DR, Gehrman, PR, Lawlor, DA, Frayling, TM, Rutter, MK, Hinds, DA, Saxena, R, Weedon, MN, Agee, M, Alipanahi, B, Auton, A, Bell, RK, Bryc, K, Elson, SL, Fontanillas, P, Furlotte, NA, Huber, KE, Kleinman, A, Litterman, NK, McCreight, JC, McIntyre, MH, Mountain, JL, Noblin, ES, Northover, CAM, Pitts, SJ, Sathirapongsasuti, JF, Sazonova, OV, Shelton, JF, Shringarpure, S, Tian, C, Tung, JY, Vacic, V, Wilson, CH
Publikováno v:
Nature Communications, 10:343. Nature Publishing Group
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=narcis______::6a0d6d8238cb2004d7e6f9a61864f37f
https://pure.eur.nl/en/publications/8dac0919-e9fa-43b2-aad6-18890b4439f0
https://pure.eur.nl/en/publications/8dac0919-e9fa-43b2-aad6-18890b4439f0
Autor:
Lambe, T, Frew, E, Ives, NJ, Woolley, RL, Cummins, C, Brettell, EA, Barsoum, EN, Webb, NJA, Prednos Trial Team, Ray, DW
Publikováno v:
PHARMACOECONOMICS
The Paediatric Quality of Life Inventory (PedsQL™) questionnaire is a widely used, generic instrument designed for measuring health-related quality of life (HRQoL); however, it is not preference-based and therefore not suitable for cost-utility ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5e12bb29327e04cf0bc8ae576777b99
Autor:
Hopwood, TW, Hall, S, Begley, N, Forman, R, Brown, S, Vonslow, R, Saer, B, Little, MC, Murphy, EA, Hurst, RJ, Ray, DW, Macdonald, AS, Brass, A, Bechtold, DA, Gibbs, JE, Loudon, AS, Else, KJ
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports
Hopwood, T, Hall, S, Begley, N, Forman, R, Brown, S, Vonslow, R, Saer, B, Little, M, Murphy, E, Hurst, R, Ray, D, MacDonald, A, Brass, A, Bechtold, D, Gibbs, J, Loudon, A & Else, K 2018, ' The circadian regulator BMAL1 programmes responses to parasitic worm infection via a dendritic cell clock ', Scientific Reports, vol. 8, 3782 . https://doi.org/10.1038/s41598-018-22021-5
Scientific Reports
Hopwood, T, Hall, S, Begley, N, Forman, R, Brown, S, Vonslow, R, Saer, B, Little, M, Murphy, E, Hurst, R, Ray, D, MacDonald, A, Brass, A, Bechtold, D, Gibbs, J, Loudon, A & Else, K 2018, ' The circadian regulator BMAL1 programmes responses to parasitic worm infection via a dendritic cell clock ', Scientific Reports, vol. 8, 3782 . https://doi.org/10.1038/s41598-018-22021-5
Resistance to the intestinal parasitic helminth Trichuris muris requires T-helper 2 (TH2) cellular and associated IgG1 responses, with expulsion typically taking up to 4 weeks in mice. Here, we show that the time-of-day of the initial infection affec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::f9faa0521878b2d1b8eca92e1d1ccd0d
http://ora.ox.ac.uk/objects/uuid:
http://ora.ox.ac.uk/objects/uuid:
Publikováno v:
Reynolds, JA, Haque, S, Williamson, K, Ray, D W, Alexander, MY & Bruce, I N 2016, ' Vitamin D improves endothelial dysfunction and restores myeloid angiogenic cell function via reduced CXCL-10 expression in systemic lupus erythematosus. ', Scientific Reports, vol. 6 . https://doi.org/10.1038/srep22341
Reynolds, JA, Haque, S, Williamson, K, Ray, D W, Alexander, MY & Bruce, I N 2016, ' Vitamin D improves endothelial dysfunction and restores myeloid angiogenic cell function via reduced CXCL-10 expression in systemic lupus erythematosus. ' Scientific Reports, vol. 6 . https://doi.org/10.1038/srep22341
Reynolds, JA, Haque, S, Williamson, K, Ray, D W, Alexander, MY & Bruce, I N 2016, ' Vitamin D improves endothelial dysfunction and restores myeloid angiogenic cell function via reduced CXCL-10 expression in systemic lupus erythematosus. ' Scientific Reports, vol. 6 . https://doi.org/10.1038/srep22341
Patients with systemic lupus erythematosus (SLE) have accelerated cardiovascular disease and dysfunctional endothelial repair mechanisms. Myeloid angiogenic cells (MACs), derived from circulating monocytes, augment vascular repair by paracrine secret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::49f71fb006b36b0713944854bf593d8c
Autor:
Whetton, Anthony, Berry, AA, Matthews, Laura C, Morgan, DJ, Poolman, TM, Bauer, K, Kramer, F, Spiller, DG, Richardson, RV, Chapman, KE, Farrow, SN, Norman, MR, Taylor, SS, Williamson, AJK, Tuckermann, JP, White, M R, Ray, DW.
Publikováno v:
Whetton, A, Berry, AA, Matthews, L C, Morgan, DJ, Poolman, TM, Bauer, K, Kramer, F, Spiller, DG, Richardson, RV, Chapman, KE, Farrow, SN, Norman, MR, Taylor, SS, Williamson, AJK, Taylor, SS, Tuckermann, JP, White, M R & Ray, DW 2015, ' The glucocorticoid receptor regulates accurate chromosome segregation and is associated with malignancy ', Proceedings of the National Academy of Sciences, vol. 12, no. 17, pp. 5479 .
The glucocorticoid receptor (GR) is a member of the nuclear receptor superfamily, which controls programs regulating cell proliferation, differentiation, and apoptosis. We have identified an unexpected role for GR in mitosis. We discovered that speci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______3818::8b7f31bdacf902acdb0aacd4831b8891
https://www.research.manchester.ac.uk/portal/en/publications/the-glucocorticoid-receptor-regulates-accurate-chromosome-segregation-and-is-associated-with-malignancy(8b1243c4-bad0-4a4f-8313-ce287a4acf3a).html
https://www.research.manchester.ac.uk/portal/en/publications/the-glucocorticoid-receptor-regulates-accurate-chromosome-segregation-and-is-associated-with-malignancy(8b1243c4-bad0-4a4f-8313-ce287a4acf3a).html