Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Rawny Galdino Gouveia"'
Autor:
Sâmia Sousa Duarte, Daiana Karla Frade Silva, Thaís Mangeon Honorato Lisboa, Rawny Galdino Gouveia, Camyla Caroliny Neves de Andrade, Valgrícia Matias de Sousa, Rafael Carlos Ferreira, Ricardo Olimpio de Moura, Joilly Nilce Santana Gomes, Patricia Mirella da Silva, Fátima de Lourdes Assunção Araújo de Azeve, Tatjana S. L. Keesen, Juan Carlos Ramos Gonçalves, Leônia Maria Batista, Marianna Vieira Sobral
Publikováno v:
Pharmacological Reports. 74:545-554
Acridine compounds have been described as promising anticancer agents. Previous studies showed that (E)-1'-((4-chlorobenzylidene)amino)-5'-oxo-1',5'-dihydro-10H-spiro[acridine-9,2'-pyrrole]-4'-carbonitrile (AMTAC-06), a spiro-acridine compound, has a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1f47546431ca7835b18b4ffb6af94cf
https://doi.org/10.1007/s43440-022-00357-0
https://doi.org/10.1007/s43440-022-00357-0
Autor:
Marcelo Sobral da Silva, Ranna Beatris de Lima Souza, Josean Fechine Tavares, Vicente Carlos de Oliveira Costa, Rawny Galdino Gouveia, José Iranildo Miranda de Melo, Augusto Lopes Souto, Marianna Vieira Sobral, Yuri Mangueira do Nascimento
Publikováno v:
Phytochemistry Letters. 39:144-150
The chemical investigation of Macroptilium martii (Fabaceae) has provided the identification of twelve compounds obtained by liquid chromatography coupled to mass spectrometry (LC–MS/MS), among which, a new flavonoid: isorhamnetin-3-O-galactose-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07b5866d996f887f05fe8634a470c3b4
https://doi.org/10.1016/j.phytol.2020.08.001
https://doi.org/10.1016/j.phytol.2020.08.001
Anticancer Effect of a Spiro-acridine Compound Involves Immunomodulatory and Anti-angiogenic Actions
Autor:
Rafael Carlos Ferreira, Sandra Rodrigues-Mascarenhas, Rawny Galdino Gouveia, Davi Felipe Farias, Thaís Lisboa, Sâmia Sousa Duarte, Marianna Vieira Sobral, Patricia Mirella da Silva, Ricardo Olímpio de Moura, Juliana Souza, Karina Carla de Paula Medeiros, Éssia de Almeida Lima, Juan Carlos Ramos Gonçalves, Daiana Karla Frade Silva, Jamire Muriel Da Silva
Publikováno v:
Anticancer Research. 40:5049-5057
BACKGROUND/AIM Studies with acridine compounds have reported anticancer effects. Herein, we evaluated the toxicity and antitumor effect of the (E)-1'-((4-chlorobenzylidene)amino)-5'-oxo-1',5'-dihydro-10H-spiro[acridine-9,2'-pyrrole]-4'-carbonitrile (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2a8fa24e6962d187001a440de27baf8
https://doi.org/10.21873/anticanres.14508
https://doi.org/10.21873/anticanres.14508
Autor:
Túlio Ricardo Couto de Lima Souza, Sinara Mônica Vitalino de Almeida, Ricardo Olímpio de Moura, Jamerson Ferreira de Oliveira, Amélia Galdino Ribeiro, Miguel Ângelo Santos Pinheiro Segundo, Maria do Carmo Alves de Lima, Rawny Galdino Gouveia
Publikováno v:
Bioorganicmedicinal chemistry. 26(22)
Nine new spiroacridine derivatives were synthetized by introducing cyano-N-acylhydrazone group between the acridine and phenyl-substituted rings followed by spontaneous cyclization. The new compounds were assayed for their DNA binding properties, hum
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95bbc7454e850571206422ca39012e1
https://pubmed.ncbi.nlm.nih.gov/30420325
https://pubmed.ncbi.nlm.nih.gov/30420325