Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Rawien Balesar"'
Autor:
Luuk E. de Vries, Aldo Jongejan, Jennifer Monteiro Fortes, Rawien Balesar, Annemieke J. M. Rozemuller, Perry D. Moerland, Inge Huitinga, Dick F. Swaab, Joost Verhaagen
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-24 (2024)
Abstract Some individuals show a discrepancy between cognition and the amount of neuropathological changes characteristic for Alzheimer’s disease (AD). This phenomenon has been referred to as ‘resilience’. The molecular and cellular underpinnin
Externí odkaz:
https://doaj.org/article/e03528769b2a4a3cb0f3eb56cfdfb93b
Autor:
Yang-Jian Qi, Yun-Rong Lu, Li-Gen Shi, Jeroen A. A. Demmers, Karel Bezstarosti, Erikjan Rijkers, Rawien Balesar, Dick Swaab, Ai-Min Bao
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract We investigated for the first time the proteomic profiles both in the dorsolateral prefrontal cortex (DLPFC) and anterior cingulate cortex (ACC) of major depressive disorder (MDD) and bipolar disorder (BD) patients. Cryostat sections of DLPF
Externí odkaz:
https://doaj.org/article/35fd82e7a6684604b3dbe5d2b5cd1c76
Autor:
Lei Guo, Yang-Jian Qi, Hong Tan, Dan Dai, Rawien Balesar, Arja Sluiter, Joop van Heerikhuize, Shao-Hua Hu, Dick F. Swaab, Ai-Min Bao
Publikováno v:
EBioMedicine, Vol 84, Iss , Pp 104266- (2022)
Summary: Background: Oxytocin (OXT) and corticotropin-releasing hormone (CRH) are both produced in hypothalamic paraventricular nucleus (PVN). Central CRH may cause depression-like symptoms, while peripheral higher OXT plasma levels were proposed to
Externí odkaz:
https://doaj.org/article/9ad715b556a8455c8182c0721a5b7df8
Autor:
Malte Brammerloh, Markus Morawski, Isabel Friedrich, Tilo Reinert, Charlotte Lange, Primož Pelicon, Primož Vavpetič, Steffen Jankuhn, Carsten Jäger, Anneke Alkemade, Rawien Balesar, Kerrin Pine, Filippos Gavriilidis, Robert Trampel, Enrico Reimer, Thomas Arendt, Nikolaus Weiskopf, Evgeniya Kirilina
Publikováno v:
NeuroImage, Vol 239, Iss , Pp 118255- (2021)
In Parkinson’s disease, the depletion of iron-rich dopaminergic neurons in nigrosome 1 of the substantia nigra precedes motor symptoms by two decades. Methods capable of monitoring this neuronal depletion, at an early disease stage, are needed for
Externí odkaz:
https://doaj.org/article/924020a0d268449c83f36df87856f251
Autor:
Anneke Alkemade, Kerrin Pine, Evgeniya Kirilina, Max C. Keuken, Martijn J. Mulder, Rawien Balesar, Josephine M. Groot, Ronald L. A. W. Bleys, Robert Trampel, Nikolaus Weiskopf, Andreas Herrler, Harald E. Möller, Pierre-Louis Bazin, Birte U. Forstmann
Publikováno v:
Frontiers in Neuroanatomy, Vol 14 (2020)
Post mortem magnetic resonance imaging (MRI) studies on the human brain are of great interest for the validation of in vivo MRI. It facilitates a link between functional and anatomical information available from MRI in vivo and neuroanatomical knowle
Externí odkaz:
https://doaj.org/article/d77eb0b28b2b48ab999db8363131643d
Autor:
Jing Lu, Juan Zhao, Rawien Balesar, Rolf Fronczek, Qiong-Bin Zhu, Xue-Yan Wu, Shao-Hua Hu, Ai-Min Bao, Dick F. Swaab
Publikováno v:
EBioMedicine, Vol 18, Iss C, Pp 311-319 (2017)
Background: Neurophysiological and behavioral processes regulated by hypocretin (orexin) are severely affected in depression. However, alterations in hypocretin have so far not been studied in the human brain. We explored the hypocretin system change
Externí odkaz:
https://doaj.org/article/a8bcbe75bd304954ae1eb4ae2dddb4a3
Autor:
Xin‐Lu Chen, Jennifer Monteiro Fortes, Yu‐Ting Hu, Juliet van Iersel, Kang‐Ning He, Joop van Heerikhuize, Rawien Balesar, Dick Swaab, Ai‐Min Bao
Publikováno v:
Alzheimer's & dementia : the journal of the Alzheimer's Association. John Wiley and Sons Inc.
INTRODUCTION: Women are more vulnerable to Alzheimer's disease (AD) than men. The entorhinal cortex (EC) is one of the earliest structures affected in AD. We identified in cognitively intact elderly different molecular changes in the EC in relation t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b15b4073aec812b7d5921382cfa285d
https://pure.knaw.nl/portal/en/publications/927d0204-fc39-4fa8-93ae-e917b0dbd59c
https://pure.knaw.nl/portal/en/publications/927d0204-fc39-4fa8-93ae-e917b0dbd59c
Autor:
Lin Zhang, Ronald W.H. Verwer, Joop van Heerikhuize, Rawien Balesar, Felipe Correa-da-Silva, Zala Slabe, Paul J. Lucassen, Dick F. Swaab
Imbalanced purine metabolism is a key neurological basis for suicide and mood disorders (MD), wherein purinergic receptors in stress-sensitive cerebral regions are thought to be differentially activated. A hippocampal network that links the hypothala
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::18e232da1abc912fe911cba6dfa812c1
https://doi.org/10.1101/2022.11.22.516142
https://doi.org/10.1101/2022.11.22.516142
Autor:
Hugo McGurran, Jackson Boonstra, Ai-Min Bao, Dick F. Swaab, Rawien Balesar, Arja A. Sluiter, Jochem Stormmesand, Yu-Ting Hu, Ronald W.H. Verwer
Publikováno v:
Neuropathology and Applied Neurobiology, 47, 958-966. Wiley-Blackwell
AIMS Women are more vulnerable to Alzheimer's disease (AD) than men. We investigated (i) whether and at what age the AD hallmarks, that is, β-amyloid (Aβ) and hyperphosphorylated Tau (p-Tau) show sex differences; and (ii) whether such sex differenc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b54b71e283b5c35f1ed8dcef714e414b
https://doi.org/10.1111/nan.12729
https://doi.org/10.1111/nan.12729
Publikováno v:
Annals of Neurology, 91(2), 282-288. WILEY
Annals of Neurology
Annals of Neurology, 91, 282-288. John Wiley and Sons Inc.
Annals of Neurology
Annals of Neurology, 91, 282-288. John Wiley and Sons Inc.
Narcolepsy type 1 (NT1) is a chronic sleep disorder correlated with loss of hypocretin(orexin). In NT1 post-mortem brains, we observed 88% reduction in corticotropin-releasing hormone (CRH)-positive neurons in the paraventricular nucleus (PVN) and si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8c3dd1eb483f2902fb3a58634533766
https://hdl.handle.net/1887/3497495
https://hdl.handle.net/1887/3497495