Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rawan Alraish"'
Autor:
Rawan Alraish, Sebastian G. Wicha, Otto R. Frey, Anka C. Roehr, Johann Pratschke, Martin Stockmann, Tilo Wuensch, Magnus Kaffarnik
Publikováno v:
Annals of Intensive Care, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract Background In critically ill patients, tigecycline (TGC) remains an important therapeutic option due to its efficacy against multiresistant Gram-positive and Gram-negative bacteria. TGC is metabolized and eliminated predominantly by the live
Externí odkaz:
https://doaj.org/article/ed651372be7f461492268892b1da5ad3
Publikováno v:
Antibiotics, Vol 11, Iss 4, p 479 (2022)
This study investigated tigecycline exposure in critically ill patients from a population pharmacokinetic perspective to support rational dosing in intensive care unit (ICU) patients with acute and chronic liver impairment. A clinical dataset of 39 p
Externí odkaz:
https://doaj.org/article/b30d8e86a21245a98da966b2038b08bc
Autor:
Sebastian G. Wicha, Rawan Alraish, Magnus Kaffarnik, Anka C Roehr, Martin Stockmann, Otto R Frey, Tilo Wuensch, Johann Pratschke
Publikováno v:
Technology and Health Care. 30:309-321
BACKGROUND: Critically ill patients commonly suffer from infections that require antimicrobial therapy. In previous studies, liver dysfunction was shown to have an essential impact on the dose selection in these patients. This pilot study aims to ass
Autor:
Rawan, Alraish, Sebastian G, Wicha, Otto R, Frey, Anka C, Roehr, Johann, Pratschke, Martin, Stockmann, Tilo, Wuensch, Magnus, Kaffarnik
Publikováno v:
Annals of Intensive Care, Vol 10, Iss 1, Pp 1-9 (2020)
Annals of Intensive Care
Annals of Intensive Care
Background In critically ill patients, tigecycline (TGC) remains an important therapeutic option due to its efficacy against multiresistant Gram-positive and Gram-negative bacteria. TGC is metabolized and eliminated predominantly by the liver. Critic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5878a2188bd13a9b19d57e7ecefcdb44
https://doi.org/10.17169/refubium-28043
https://doi.org/10.17169/refubium-28043
Autor:
Tilo Wuensch, Martin Stockmann, Magnus Kaffarnik, Rawan Alraish, Anka C Roehr, Johann Pratschke, Otto R Frey, Sebastian G. Wicha
Publikováno v:
International Journal of Antimicrobial Agents. 50:557-563
Patients in the intensive care unit frequently require antibiotic treatment. Liver impairment poses substantial challenges for dose selection in these patients. The aim of the present pilot study was to assess the novel maximal liver function capacit