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Autor:
Rizwan, Mumtaz, Francesco, Trepiccione, J Christopher, Hennings, Antje K, Huebner, Bettina, Serbin, Nicolas, Picard, A K M Shahid, Ullah, Teodor G, Păunescu, Diane E, Capen, Rawad M, Lashhab, Isabelle, Mouro-Chanteloup, Seth L, Alper, Carsten A, Wagner, Emmanuelle, Cordat, Dennis, Brown, Dominique, Eladari, Christian A, Hübner
Publikováno v:
Journal of the American Society of Nephrology : JASN. 28(5)
Distal nephron acid secretion is mediated by highly specialized type A intercalated cells (A-ICs), which contain vacuolar H+-ATPase (V-type ATPase)-rich vesicles that fuse with the apical plasma membrane on demand. Intracellular bicarbonate generated