Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Rawa Ibrahim"'
Publikováno v:
STAR Protocols, Vol 4, Iss 4, Pp 102719- (2023)
Summary: Hematopoietic stem and progenitor cells depend on bone marrow (BM) stromal cells for survival. Here, we present a protocol for performing three consecutive BM transplants in mice to study the role of BM niche in supporting hematopoiesis. We
Externí odkaz:
https://doaj.org/article/7b98ecc9e8b44fb9b317add371928833
Autor:
Aseel Ibrahim, Rawa Ibrahim, Ali Abdullah, Ali Baki, Ghaidaa Khudair, Veronika Gdovinova, Peter Kopcansky
Publikováno v:
Iraqi Journal of Physics, Vol 18, Iss 47 (2020)
The nonlinear optical properties response of nematic liquid crystal (6CHBT) and the impact of doping with two kinds of nanoparticles; Fe3O4 magnetic nanoparticles and SbSI ferroelectric nanoparticles have been studied using the non-linear dynamic met
Externí odkaz:
https://doaj.org/article/a5c8c33a60db427794178d60dd120381
Autor:
Jeffrey Lam, Marion van den Bosch, Joanna Wegrzyn, Jeremy Parker, Rawa Ibrahim, Kate Slowski, Linda Chang, Sergio Martinez-Høyer, Gianluigi Condorelli, Mark Boldin, Yu Deng, Patricia Umlandt, Megan Fuller, Aly Karsan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Myelodysplastic syndrome (MDS) is characterized by altered hematopoietic stem cell (HSC) and hematopoietic progenitor cell (HPC) regulation and reduction of miR-143 and miR-145 in some subtypes. Here the authors show that miR-143/145 loss leads to HS
Externí odkaz:
https://doaj.org/article/790c5842cee2493c94acd0bef130e50e
Publikováno v:
Pharmacy Practice (1886-3655); Jul-Sep2024, Vol. 22 Issue 3, p1-8, 8p
Autor:
Patricia Umlandt, Linda Chang, Melody Lu, Jeremy Parker, Megan Fuller, Joanna Wegrzyn-Woltosz, Aly Karsan, Jenny Li, Jeffrey C. F. Lam, Aparna Gopal, Rawa Ibrahim
Activation of inflammatory pathways is associated with bone marrow failure syndromes, but how specific molecules impact on the marrow microenvironment is not well elucidated. We report a novel role for the miR-145 target, Toll/Interleukin-1 receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab03d8a626bc0630fa0c428898cc251
Autor:
Mark Boldin, Linda Chang, Gianluigi Condorelli, Joanna Wegrzyn, Megan Fuller, Jeffrey C. F. Lam, Sergio Martinez-Høyer, Marion van den Bosch, Jeremy Parker, Yu Deng, Kate Slowski, Rawa Ibrahim, Patricia Umlandt, Aly Karsan
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
Nature Communications
Nature Communications
Expression of miR-143 and miR-145 is reduced in hematopoietic stem/progenitor cells (HSPCs) of myelodysplastic syndrome patients with a deletion in the long arm of chromosome 5. Here we show that mice lacking miR-143/145 have impaired HSPC activity w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f773f46b0c8d911ee70032b28d6c50fd
http://link.springer.com/article/10.1038/s41467-018-04831-3
http://link.springer.com/article/10.1038/s41467-018-04831-3
Autor:
Jenny Li, Melody Lu, Megan Fuller, Aly Karsan, Aparna Gopal, Linda Ya-Ting Chang, Jeremy Parker, Rawa Ibrahim, Patricia Umlandt, Jeff Lam, Jessica Tran
Publikováno v:
Blood. 138:2169-2169
The myelodysplastic syndrome (MDS) are a group of hematological malignancies with the propensity to develop into either acute myeloid leukemia (AML) or bone marrow failure (BMF). Dysregulation of immune and inflammatory responses has been implicated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77da8b653d0a8aacae71c352f0c194ce
https://doi.org/10.1182/blood-2021-149245
https://doi.org/10.1182/blood-2021-149245
Publikováno v:
Experimental Hematology. 100:S75
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e69842022d0bf971088e28cbaee471b8
https://doi.org/10.1016/j.exphem.2021.12.286
https://doi.org/10.1016/j.exphem.2021.12.286
Autor:
Linda Chang, Patricia Umlandt, Angela Mo, Rawa Ibrahim, Rod Docking, Aly Karsan, Gerben Duns, Jeremy Parker
Publikováno v:
Experimental Hematology. 76:S78
Acute myeloid leukemia (AML) is the most common adult leukemia, and AML patients have a 5-year survival rate of We performed quantitative tandem mass spectrometric analysis of FBXO11 co-immunoprecipitating proteins in FBXO11 CRISPR/Cas9 knockout (KO)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7b3ac3fc518781c5f452e36fc628ad31
https://doi.org/10.1016/j.exphem.2019.06.407
https://doi.org/10.1016/j.exphem.2019.06.407
Autor:
Aly Karsan, Rawa Ibrahim, Alexandre Patenaude, Patricia Umlandt, Megan Fuller, Connie J. Eaves, Stefan Woerher, Fred Wong, Alastair H. Kyle, Andrew I. Minchinton, Sandy Unger, Jeremy Parker
Publikováno v:
Microvascular research. 101
Pericytes are perivascular support cells, the origin of which in tumor tissue is not clear. Recently, we identified a Tie1(+) precursor cell that differentiates into vascular smooth muscle, in a Notch-dependent manner. To understand the involvement o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5d52eef7615388c572d558c00632e63
https://pubmed.ncbi.nlm.nih.gov/26092680
https://pubmed.ncbi.nlm.nih.gov/26092680