Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Ravshan Burikhanov"'
Autor:
Nathalia Araujo, James Sledziona, Sunil K. Noothi, Ravshan Burikhanov, Nikhil Hebbar, Saptadwipa Ganguly, Tripti Shrestha-Bhattarai, Beibei Zhu, Wendy S. Katz, Yi Zhang, Barry S. Taylor, Jinze Liu, Li Chen, Heidi L. Weiss, Daheng He, Chi Wang, Andrew J. Morris, Lisa A. Cassis, Mariana Nikolova-Karakashian, Prabhakar R. Nagareddy, Olle Melander, B. Mark Evers, Philip A. Kern, Vivek M. Rangnekar
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Prostate apoptosis response-4 (Par-4) is a tumor suppressor that induces apoptosis in cancer cells. However, the physiological function of Par-4 remains unknown. Here we show that conventional Par-4 knockout (Par-4-/-) mice and adipocyte-specific Par
Externí odkaz:
https://doaj.org/article/4120df1ef9614b949185e69e897e61c9
Autor:
Ravshan Burikhanov, Nikhil Hebbar, Sunil K. Noothi, Nidhi Shukla, James Sledziona, Nathália Araujo, Meghana Kudrimoti, Qing Jun Wang, David S. Watt, Danny R. Welch, Jodi Maranchie, Akihiro Harada, Vivek M. Rangnekar
Publikováno v:
Cell Reports, Vol 18, Iss 2, Pp 508-519 (2017)
Summary: The induction of tumor suppressor proteins capable of cancer cell apoptosis represents an attractive option for the re-purposing of existing drugs. We report that the anti-malarial drug, chloroquine (CQ), is a robust inducer of Par-4 secreti
Externí odkaz:
https://doaj.org/article/3ebeceb7b56a457eb08f0dec28efe808
Autor:
Ravshan Burikhanov, Tripti Shrestha-Bhattarai, Nikhil Hebbar, Shirley Qiu, Yanming Zhao, Gerard P. Zambetti, Vivek M. Rangnekar
Publikováno v:
Cell Reports, Vol 6, Iss 2, Pp 271-277 (2014)
The guardian of the genome, p53, is often mutated in cancer and may contribute to therapeutic resistance. Given that p53 is intact and functional in normal tissues, we harnessed its potential to inhibit the growth of p53-deficient cancer cells. Speci
Externí odkaz:
https://doaj.org/article/078f8ac69c4d4afea76a6f3e5ec2e423
Autor:
Vivek M. Rangnekar, Kojo S.J. Elenitoba-Johnson, Yanming Zhao, Shirley Qiu, Nidhi Shukla, Ravshan Burikhanov, Nikhil Hebbar
SUPPLEMENTARY DATA (1) Figure S1 shows that Paclitaxel induces paracrine apoptosis in Paclitaxel-resistant cells by inducing the secretion of a Par-4-like secreted factor. (2) Figure S2 shows that Par-4 is cleaved to produce the 15 kDa fragment. (3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ad73d02ed40d2ab034a607b10f4efb6
https://doi.org/10.1158/0008-5472.22414463
https://doi.org/10.1158/0008-5472.22414463
Autor:
Vivek M. Rangnekar, Kojo S.J. Elenitoba-Johnson, Yanming Zhao, Shirley Qiu, Nidhi Shukla, Ravshan Burikhanov, Nikhil Hebbar
Primary tumors are often heterogeneous, composed of therapy-sensitive and emerging therapy-resistant cancer cells. Interestingly, treatment of therapy-sensitive tumors in heterogeneous tumor microenvironments results in apoptosis of therapy-resistant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb808c42fad9faa2f602fa2473f2bb36
https://doi.org/10.1158/0008-5472.c.6508985.v1
https://doi.org/10.1158/0008-5472.c.6508985.v1
Autor:
Mansoor M. Ahmed, Vivek M. Rangnekar, Mohammed Mohiuddin, Shahin Shajahan, Sabapathi Satishkumar, Seema Gupta, Ravshan Burikhanov, Nuan Cui, Mohammed M. Shareef
Supplementary Figure 1 from Role of Tumor Necrosis Factor-α and TRAIL in High-Dose Radiation–Induced Bystander Signaling in Lung Adenocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17270b64a2c74f5065210ed48aa5635b
https://doi.org/10.1158/0008-5472.22371027
https://doi.org/10.1158/0008-5472.22371027
Autor:
Vivek M. Rangnekar, Brett Spear, Subbarao Bondada, C. Darrell Jennings, Subodh M. Lele, Shirley Qiu, Ravshan Burikhanov, Yanming Zhao
Supplementary Figures 1-3 from Cancer Resistance in Transgenic Mice Expressing the SAC Module of Par-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353e97588a9b1fcebced733392a8390a
https://doi.org/10.1158/0008-5472.22368681.v1
https://doi.org/10.1158/0008-5472.22368681.v1
Autor:
Mansoor M. Ahmed, Vivek M. Rangnekar, Mohammed Mohiuddin, Shahin Shajahan, Sabapathi Satishkumar, Seema Gupta, Ravshan Burikhanov, Nuan Cui, Mohammed M. Shareef
Supplementary Figure 3 from Role of Tumor Necrosis Factor-α and TRAIL in High-Dose Radiation–Induced Bystander Signaling in Lung Adenocarcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7888a70c4f8d1534b0ff924139e082
https://doi.org/10.1158/0008-5472.22371021
https://doi.org/10.1158/0008-5472.22371021
Autor:
Vivek M. Rangnekar, Craig Horbinski, Subodh M. Lele, Nikhil Hebbar, Nidhi Shukla, Shirley Qiu, Tripti Shrestha-Bhattarai, Ravshan Burikhanov
PDF file - 3241KB, Figure S1. Apoptosis by extracellular Par-4 is augmented by NF-kappaB inhibition. Figure S2. UACA binds to Par-4 and is regulated by NF-kappaB. Figure S3. Correlation between nuclear NF-kappaB activity and UACA expression. Figure S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f9b84bfc4d0df97fe46c3ed87bf7bc2
https://doi.org/10.1158/0008-5472.22399968.v1
https://doi.org/10.1158/0008-5472.22399968.v1
Autor:
Vivek M. Rangnekar, Brett Spear, Subbarao Bondada, C. Darrell Jennings, Subodh M. Lele, Shirley Qiu, Ravshan Burikhanov, Yanming Zhao
Supplementary Figure Legends 1-3 from Cancer Resistance in Transgenic Mice Expressing the SAC Module of Par-4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18d64fd64a0255daf6cb33614ec876af
https://doi.org/10.1158/0008-5472.22368684
https://doi.org/10.1158/0008-5472.22368684