Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ravivaj S. Pillai"'
Autor:
Rajkumar Malayandi, Srinivas Mutalik, Phani Krishna Kondamudi, Phani Prasanth Tirumalasetty, Ravivaj S. Pillai
Publikováno v:
AAPS PharmSciTech. 17:588-596
The present study aims to develop the correlation between in vitro and in vivo skin permeation of lidocaine in its transdermal patch. In order to minimize the run-to-run variability during in vitro skin permeation studies, release normalized cumulati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64dd538e1a806b90b4d35b6769cf6ed5
https://doi.org/10.1208/s12249-015-0390-1
https://doi.org/10.1208/s12249-015-0390-1
Publikováno v:
AAPS PharmSciTech. 19(1)
Solubility challenge for a poorly water-soluble drug gets further intensified when it is weakly ionic because the most common solubility enhancement technique, salt formation, becomes less feasible. Salt screening for such drugs often concludes with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b04e9891d7d7e3fca59d1b82ab705255
https://pubmed.ncbi.nlm.nih.gov/28721630
https://pubmed.ncbi.nlm.nih.gov/28721630
Publikováno v:
Drug Development and Industrial Pharmacy. 41:124-130
Design of experiments (DOE), a component of Quality by Design (QbD), is systematic and simultaneous evaluation of process variables to develop a product with predetermined quality attributes. This article presents a case study to understand the effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894d540ce6b99dfefdcb70e187af3d9b
https://doi.org/10.3109/03639045.2013.850709
https://doi.org/10.3109/03639045.2013.850709
Autor:
Khalid A. Ansari, Neeraj S. Kaul, Deepak Kumar, Devendra N. Ridhurkar, Ravivaj S. Pillai, Sanju Dhawan, T. Krishnamurthy
Publikováno v:
Drug Development and Industrial Pharmacy. 39:1783-1792
Aprepitant (APR) is a water insoluble drug approved for the treatment of chemotherapy induced nausea and vomiting (CINV) and post-operative nausea and vomiting (PONV). The innovator Emend® is a formulation incorporating drug nanoparticles with good
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76304e54b9ed5407f21aebcbb993546d
https://doi.org/10.3109/03639045.2012.737331
https://doi.org/10.3109/03639045.2012.737331
Publikováno v:
Current Drug Delivery. 8:661-666
The aim of this study was to formulate polyethylene glycol (PEG) based nanoparticulate camptothecin analog for oral administration and to evaluate its pharmacological activity. Camptothecin analog (CA) belongs to topoisomerase-I inhibitor class of co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c6cff930b44365ccdfd5f91e783263
https://doi.org/10.2174/156720111797635469
https://doi.org/10.2174/156720111797635469
Publikováno v:
Drug Delivery. 18:294-303
This work focused on the developmental aspects, pharmacokinetic evaluation, and pharmacological assessment of a drug inclusion complex for a novel camptothecin analog (CA) and 2-hydroxypropyl-β-cyclodextrin (HP-β-CD). Camptothecins analog belong to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::861a3767e45a7a6f6918c47f2395d387
https://doi.org/10.3109/10717544.2010.544689
https://doi.org/10.3109/10717544.2010.544689
Publikováno v:
AAPS PharmSciTech. 11:9-17
Sparingly, water-soluble drugs such as candesartan cilexetil offer challenges in developing a drug product with adequate bioavailability. The objective of the present study was to develop and characterize self-microemulsifying drug delivery system (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e38c058e107a2565f643dadc820de5b4
https://doi.org/10.1208/s12249-009-9347-6
https://doi.org/10.1208/s12249-009-9347-6
Autor:
Thilekkumar Muniyappan, Ravivaj S. Pillai, Raghavendra Prabhu, Shradhanjali Basa, Pradeep Jairao Karatgi
Publikováno v:
Drug Development and Industrial Pharmacy. 34:1209-1218
The objective of this study was to develop a tablet formulation of ketoconazole incorporating drug nanoparticles to enhance saturation solubility and dissolution velocity for enhancing bioavailability and reducing variability in systemic exposure. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::494647cc87ac1530b9aa18210826569f
https://doi.org/10.1080/03639040802005024
https://doi.org/10.1080/03639040802005024
Publikováno v:
Journal of Applied Physiology. 84:717-725
Pillai, Raviraj S., Donovan B. Yeates, Irving F. Miller, and Anthony J. Hickey. Controlled dissolution from wax-coated aerosol particles in canine lungs. J. Appl. Physiol. 84(2): 717–725, 1998.—Treatment of pulmonary and systemic diseases may be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::033bf146a07c2088e1e4dbfbd1b4f110
https://doi.org/10.1152/jappl.1998.84.2.717
https://doi.org/10.1152/jappl.1998.84.2.717
Autor:
Paul Blezinger, Deepa Deshpande, John G. Duguid, Ravivaj S. Pillai, Bruce Freimark, Alain Rolland
Publikováno v:
Pharmaceutical Research. 15:1340-1347
Purpose. Cationic lipids are capable of transferring foreign genes to the pulmonary epithelium in vivo. It is becoming increasingly clear that factors other than lipid molecular structure also influence efficiency of delivery using cationic lipid sys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04c19d01b394355e7ca5dd92aa601af4
https://doi.org/10.1023/a:1011933117509
https://doi.org/10.1023/a:1011933117509