Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ravit Madar"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Assessment of spatial learning abilities is central to behavioral neuroscience and a useful tool for animal model validation and drug development. However, biases introduced by the apparatus, environment, or experimentalist represent a criti
Externí odkaz:
https://doaj.org/article/54c42c3dcd374142a02717b458ef7105
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-19 (2021)
Illouz et al vaccinated wildtype female mice against human Amyloid-β (Aβ) prior to them being bred with 5xFAD males, which model Aβ deposition, as occurs in Alzheimer’s Disease (AD) and Down’s syndrome (DS). The resultant offspring had reduced
Externí odkaz:
https://doaj.org/article/4d73926b773146d18ed0388b70fee444
Autor:
Yaeli Lev-Vachnish, Sharon Cadury, Aviva Rotter-Maskowitz, Noa Feldman, Asael Roichman, Tomer Illouz, Alexander Varvak, Raneen Nicola, Ravit Madar, Eitan Okun
Publikováno v:
Frontiers in Neuroscience, Vol 13 (2019)
Neurogenesis, the formation of new neurons in the adult brain, is important for memory formation and extinction. One of the most studied external interventions that affect the rate of adult neurogenesis is physical exercise. Physical exercise promote
Externí odkaz:
https://doaj.org/article/33ffe6f24663492daff530c79be5dc3d
Publikováno v:
Molecules, Vol 25, Iss 17, p 4013 (2020)
Risperidone (RSP) is an atypical antipsychotic drug widely used to treat schizophrenia and bipolar disorder. Nanoparticles (NPs) are being developed as in vivo targeted drug delivery systems, which cross the blood-brain barrier and improve pharmacoki
Externí odkaz:
https://doaj.org/article/01320db3a4b6495d9d661726bf088f53
Autor:
Eitan Okun, Daniel Marton, Daniel Cohen, Kathleen Griffioen, Yariv Kanfi, Tomer Illouz, Ravit Madar, Haim Y Cohen
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179681 (2017)
Sirtuins are pleiotropic NAD+ dependent histone deacetylases involved in metabolism, DNA damage repair, inflammation and stress resistance. SIRT6, a member of the sirtuin family, regulates the process of normal aging and increases the lifespan of mal
Externí odkaz:
https://doaj.org/article/3c7b7589c3b94e4a91fe35252162a281
Publikováno v:
NeuroMolecular Medicine. 24:399-404
Microglia, the primary brain-resident immune cells, protect the brain from various harmful pathogens, insulting and maintaining its homeostasis by phagocytosing extracellular particles. How microglia are metabolically regulated by their microenvironm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80820673b6750f956671da8f8439715f
https://doi.org/10.1007/s12017-022-08710-5
https://doi.org/10.1007/s12017-022-08710-5
Publikováno v:
Vaccine
Aging-related decline in immune functions, termed immunosenescence, is a primary cause of reduced protective responses to vaccines in the elderly, due to impaired induction of cellular and humoral responses to new antigens (Ag), especially if the res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2abd3658eccab4793b772c2323272c1d
https://europepmc.org/articles/PMC9237638/
https://europepmc.org/articles/PMC9237638/
Publikováno v:
Brain, behavior, and immunity
Down Syndrome (DS), the most common cause of genetic intellectual disability, is characterized by over-expression of the APP and DYRK1A genes, located on the triplicated chromosome 21. This chromosomal abnormality leads to a cognitive decline mediate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7ff10d7fefb40ee504555920dab2e6
https://doi.org/10.1016/j.bbi.2018.10.004
https://doi.org/10.1016/j.bbi.2018.10.004
Autor:
Mara Almog, Izhar Bar-Gad, Yocheved Loewenstern, Alon Korngreen, Ravit Madar, Eitan Okun, Hagar Lavian
Publikováno v:
Brain Structure and Function. 223:2673-2684
Dopamine is critical for the normal functioning of the basal ganglia, modulating both input and output nuclei of this system. The distribution and function of each of the five dopamine receptor subtypes have been studied extensively in the striatum.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f5dcbdb12aa2364806087618fbd801a
https://doi.org/10.1007/s00429-018-1657-6
https://doi.org/10.1007/s00429-018-1657-6
Publikováno v:
Journal of Neuroscience Methods. 291:28-35
Background Amyloid-β (Aβ), a hallmark of Alzheimer’s disease (AD), has long been a focus of basic and translation research in AD. Quantification and dissociation of the Aβ fractions in their soluble and insoluble forms, is a key factor in numero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f9888f52ade34c25d1aee26b3a53cd1
https://doi.org/10.1016/j.jneumeth.2017.07.022
https://doi.org/10.1016/j.jneumeth.2017.07.022