Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Raviraj Thakur"'
Autor:
Raviraj Thakur, Gene Y. Fridman
Publikováno v:
Micromachines, Vol 13, Iss 9, p 1408 (2022)
Rapid prototyping methods enable the widespread adoption of microfluidic technologies by empowering end-users from non-engineering disciplines to make devices using processes that are rapid, simple and inexpensive. In this work, we developed a liquid
Externí odkaz:
https://doaj.org/article/4738543d74a340a68aedb11693e83025
Autor:
Daniel F Q Smith, Emma Camacho, Raviraj Thakur, Alexander J Barron, Yuemei Dong, George Dimopoulos, Nichole A Broderick, Arturo Casadevall
Publikováno v:
PLoS Biology, Vol 19, Iss 5, p e3001182 (2021)
Melanin, a black-brown pigment found throughout all kingdoms of life, has diverse biological functions including UV protection, thermoregulation, oxidant scavenging, arthropod immunity, and microbial virulence. Given melanin's broad roles in the bios
Externí odkaz:
https://doaj.org/article/e24e10db44c94873aa9bbeef1eee1eec
Publikováno v:
Micromachines, Vol 12, Iss 12, p 1522 (2021)
Implantable neuromodulation devices typically have metal in contact with soft, ion-conducting nerves. These neural interfaces excite neurons using short-duration electrical pulses. While this approach has been extremely successful for multiple clinic
Externí odkaz:
https://doaj.org/article/eb8818e98e574c5c9c8bee4f8a301c4e
Publikováno v:
EMBC
Direct current (DC) has the potential not only to excite but also to inhibit neurons. This property of DC stimulus has been used for generating peripheral nerve blocks. One translational challenge of DC-based neuromodulation technologies, especially
Publikováno v:
Microfluidics and Nanofluidics. 22
Various microfluidic architectures designed for in vivo and point-of-care diagnostic applications require larger channels, autonomous actuation, and portability. In this paper, we present a normally closed microvalve design capable of fully autonomou
Publikováno v:
BioCAS
For safety reasons, commercial neural implants use charge-balanced biphasic pulses to interact with target neurons using metal electrodes. Short biphasic pulses are used to avoid irreversible electrochemical reactions at the electrode-tissue interfac
Publikováno v:
Microfluidics and Nanofluidics. 18:1425-1431
Droplet microfluidics offers an effective way for compartmentalizing samples and reagents for various biological and/or biochemical assays. However, an active control over size and frequency of individual droplets is quite difficult to achieve with o
Publikováno v:
Journal of Neural Engineering. 16:064003
Objective Implantable neuromodulation devices that have cuff electrodes are known to exert mechanical pressure on the target nerves. The amount of pressure exerted by cuff enclosures is one of the key determinants of physiological safety of these dev
Autor:
Seth M. Madren, Mithuna Thottethodi, Ahmed M. Amin, Han Sheng Chuang, T. N. Vijaykumar, Steven T. Wereley, Stephen C. Jacobson, Raviraj Thakur
Publikováno v:
Microfluidics and Nanofluidics. 15:647-659
Current lab-on-a-chip (LoC) devices are assay-specific and are custom-built for each single experiment. Performing an experiment requires scientists or engineers to go through the time-consuming process of designing, fabricating, and testing a chip b
A microfabricated microfluidic bioMEMS device to model human brain aneurisms: the aneurysm-on-a-chip
Autor:
Lisa M. Reece, Jian Wei Khor, Ahmed M. Amin, James F. Leary, Steven T. Wereley, Raviraj Thakur
Publikováno v:
SPIE Proceedings.
Aneurysms are pockets of blood that collect outside blood vessel walls forming dilatations and leaving arterial walls very prone to rupture. There is little information concerning the causes of intracranial aneurysm formation, growth, and rupture. Cu