Zobrazeno 1 - 10
of 223
pro vyhledávání: '"Ravindra Uppaluri"'
Autor:
Kelsy C. Cotto, Yang-Yang Feng, Avinash Ramu, Megan Richters, Sharon L. Freshour, Zachary L. Skidmore, Huiming Xia, Joshua F. McMichael, Jason Kunisaki, Katie M. Campbell, Timothy Hung-Po Chen, Emily B. Rozycki, Douglas Adkins, Siddhartha Devarakonda, Sumithra Sankararaman, Yiing Lin, William C. Chapman, Christopher A. Maher, Vivek Arora, Gavin P. Dunn, Ravindra Uppaluri, Ramaswamy Govindan, Obi L. Griffith, Malachi Griffith
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Analysing the regulatory consequences of mutations and splice variants at large scale in cancer requires efficient computational tools. Here, the authors develop RegTools, a software package that can identify splice-associated variants from large-sca
Externí odkaz:
https://doaj.org/article/a791b7f280e84d3d8c3cf984f3f564cd
Autor:
Donald J. Annino Jr, Rosh K. Sethi, Elisabeth E. Hansen, Sylvia Horne, Tanujit Dey, Eleni M. Rettig, Ravindra Uppaluri, Jason I. Kass, Laura A. Goguen
Publikováno v:
Laryngoscope Investigative Otolaryngology, Vol 7, Iss 6, Pp 1798-1807 (2022)
Abstract Objectives Examine accuracy and factors impacting accuracy for mandibular reconstruction with virtual surgical planning, 3D printed osteotomy guides and preoperatively bent mandibular reconstruction plate (VSP/3Dprinted‐guide/plate). Metho
Externí odkaz:
https://doaj.org/article/e59e3fa62fa24aabbc8f0e72be1fa2a2
Autor:
Nupur Nigam, Benjamin Bernard, Samantha Sevilla, Sohyoung Kim, Mohd Saleem Dar, Daniel Tsai, Yvette Robbins, Kyunghee Burkitt, Cem Sievers, Clint T. Allen, Richard L. Bennett, Theophilus T. Tettey, Benjamin Carter, Lorenzo Rinaldi, Mark W. Lingen, Houssein Sater, Elijah F. Edmondson, Arfa Moshiri, Abbas Saeed, Hui Cheng, Xiaolin Luo, Kevin Brennan, Vishal Koparde, Chen Chen, Sudipto Das, Thorkell Andresson, Abdalla Abdelmaksoud, Madhavi Murali, Seiji Sakata, Kengo Takeuchi, Raj Chari, Yusuke Nakamura, Ravindra Uppaluri, John B. Sunwoo, Carter Van Waes, Jonathan D. Licht, Gordon L. Hager, Vassiliki Saloura
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112823- (2023)
Summary: Cancers often display immune escape, but the mechanisms are incompletely understood. Herein, we identify SMYD3 as a mediator of immune escape in human papilloma virus (HPV)-negative head and neck squamous cell carcinoma (HNSCC), an aggressiv
Externí odkaz:
https://doaj.org/article/b0940346e8a34a0c84bdf4ba79034b75
Autor:
Nana Chen, Gabriel Golczer, Subhoshree Ghose, Brian Lin, Adam Langenbucher, Jason Webb, Haymanti Bhanot, Nicholas B. Abt, Derrick Lin, Mark Varvares, Martin Sattler, Ann Marie Egloff, Richard Joh, Ravindra Uppaluri, Kevin S. Emerick, Michael S. Lawrence, Srinivas Vinod Saladi
Publikováno v:
Cell Reports, Vol 39, Iss 11, Pp 110970- (2022)
Summary: Analysis of The Cancer Genome Atlas and other published data of head and neck squamous cell carcinoma (HNSCC) reveals somatic alterations of the Hippo-YAP pathway in approximately 50% of HNSCC. Better strategies to target the YAP1 transcript
Externí odkaz:
https://doaj.org/article/13be6881b6a64f958b845f078f8a66c3
Autor:
Zhe Zhang, Yi Zhang, Fan Zhang, Xiaojing Ma, Ravindra Uppaluri, Robert Haddad, Jonathan D Schoenfeld, Shengqing Gu, Joshua Keegan, James A Lederer, Xiaoqing Wang, Zexian Zeng, Jingxin Fu, Liye Zhou, Ann Marie Egloff, Fei Guo, Katie M Campbell, Peter Du, Paul Zolkind, Rachel Riley, Yasutaka Nakahori, Obi Griffith, Robert T Manguso, X Shirley Liu
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/01f7319832a544bf89d75fb5c244fa9c
Autor:
Yu Wang, Andrea Califano, Young Kim, Michael Gibson, Charles Drake, Yaomin Xu, Ravindra Uppaluri, Adam Luginbuhl, Aleksandar Obradovic, Joseph Curry, Michael Korrer, Diana Graves, Sohini Roy, Paula Hurley
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/9b377124d5e2473a8ba1f1d8a7200a3f
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Neoadjuvant immunotherapy has the potential to enhance clinical outcomes by increasing anti-tumor immune responses in the presence of abundant tumor-derived antigen in an immune microenvironment that has not been exposed to previous therapy. The curr
Externí odkaz:
https://doaj.org/article/2eacbc1846304f78864b894a58eb30e7
Tumor‐associated neutrophils (TANs) in human carcinoma‐draining lymph nodes: a novel TAN compartment
Autor:
Silvia Lonardi, Francesco Missale, Stefano Calza, Mattia Bugatti, Raffaella Vescovi, Bresciani Debora, Ravindra Uppaluri, Ann Marie Egloff, Davide Mattavelli, Davide Lombardi, Luisa Benerini Gatta, Olivia Marini, Nicola Tamassia, Elisa Gardiman, Marco A Cassatella, Patrizia Scapini, Piero Nicolai, William Vermi
Publikováno v:
Clinical & Translational Immunology, Vol 10, Iss 2, Pp n/a-n/a (2021)
Abstract Objectives The role of tumor‐associated neutrophils (TANs) in the nodal spread of cancer cells remains unexplored. The present study evaluates the occurrence and clinical significance of human nodal TANs. Methods The relevance, derivation,
Externí odkaz:
https://doaj.org/article/79f90ffa05204f2da9e4476ba7c48cee
Autor:
Hirofumi Shibata, Na Xu, Shin Saito, Liye Zhou, Ibrahim Ozgenc, Jason Webb, Cong Fu, Paul Zolkind, Ann Marie Egloff, Ravindra Uppaluri
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Head and neck squamous cell carcinomas (HNSCC) are well suited for cancer vaccination strategies. In addition to tumor-associated antigens (TAAs) and endogenous retrovirus (ERV) encoded proteins, HNSCCs have a relatively high tumor mutational burden
Externí odkaz:
https://doaj.org/article/27a54bbcb10746c0b6b6421fa9a69c5f
Autor:
Andrew G. Sikora, Kevin J. Harrington, R. Bryan Bell, Maura L. Gillison, Quynh-Thu Le, Nancy Y. Lee, Rebecca L. Lewis, Loren K. Mell, Adam Raben, Ravindra Uppaluri, Fernanda Whitworth, Dan P. Zandberg
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1 (2019)
Head and neck cancers, including those of the lip and oral cavity, nasal cavity, paranasal sinuses, oropharynx, larynx and nasopharynx represent nearly 700,000 new cases and 380,000 deaths worldwide per annum, and account for over 10,000 annual death
Externí odkaz:
https://doaj.org/article/ec9804eba34044ffba07cada41e82843