Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ravindra Thakkar"'
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 6875 (2024)
Enhanced electrical activity in detrusor smooth muscle (DSM) cells is a key factor in detrusor overactivity which causes overactive bladder pathological disorders. Transient receptor potential melastatin-4 (TRPM4) channels, which are calcium-activate
Externí odkaz:
https://doaj.org/article/5c21630989ab4c4e8763385c7c8202f5
Autor:
Susumu Ishiguro, Deepa Upreti, Molly Bassette, E.R. Azhagiya Singam, Ravindra Thakkar, Mayme Loyd, Makoto Inui, Jeffrey Comer, Masaaki Tamura
Publikováno v:
Translational Oncology, Vol 16, Iss , Pp 101337- (2022)
A novel peptide that interferes with the PD-1/PD-L1 immune checkpoint pathway, termed PD-L1 inhibitory peptide 3 (PD-L1ip3), was computationally designed, experimentally validated for its specific binding to PD-L1, and evaluated for its antitumor eff
Externí odkaz:
https://doaj.org/article/ee3acc8c0759474380d074c568e4c9c7
Autor:
Susumu Ishiguro, Mary Roth, Ruth Welti, Mayme Loyd, Ravindra Thakkar, Morgan Phillips, Nicole Robben, Deepa Upreti, Ayaka Nakashima, Kengo Suzuki, Jeffrey Comer, Masaaki Tamura
Publikováno v:
Nutrients, Vol 14, Iss 14, p 2901 (2022)
A water extract derived from the isolated cell walls of Chlorella sorokiniana (C. sorokiniana, Chlorella water extract, CWE) was analyzed for the presence of lipopolysaccharide (LPS)-related material via the Limulus amebocyte lysate (LAL) assay and e
Externí odkaz:
https://doaj.org/article/8c9bbe792f394bd4ad71407c943ab644
Autor:
Susumu Ishiguro, Deepa Upreti, Nicole Robben, Riley Burghart, Mayme Loyd, Damilola Ogun, Tran Le, Jennifer Delzeit, Arashi Nakashima, Ravindra Thakkar, Ayaka Nakashima, Kengo Suzuki, Jeffrey Comer, Masaaki Tamura
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 127, Iss , Pp 110166- (2020)
The partially purified water extract from Euglena gracilis (EWE) was evaluated for its antitumor and immunomodulatory effects in cell cultures and in a mouse orthotopic lung carcinoma allograft model. In two-dimensional cell culture, the EWE treatmen
Externí odkaz:
https://doaj.org/article/daca489ba7fc4e85b7b0ee359fe87143
Autor:
Susumu Ishiguro PhD, Nicole Robben BSc, Riley Burghart BSc, Paige Cote BSc, Sarah Greenway BSc, Ravindra Thakkar MS, Deepa Upreti MS, Ayaka Nakashima MS, Kengo Suzuki PhD, Jeffrey Comer PhD, Masaaki Tamura DVM, PhD
Publikováno v:
Integrative Cancer Therapies, Vol 19 (2020)
A colon cancer growth inhibitor partially purified from the isolated cell wall membrane fraction of Chlorella sorokiniana , here referred to as Chlorella membrane factor (CMF), was evaluated for its antitumor and immunomodulatory effects in cell cult
Externí odkaz:
https://doaj.org/article/57ba2a9a3c9a4831ade3ac54c7ae9aa4
Publikováno v:
Annals of Indian Academy of Neurology, Vol 19, Iss 2, Pp 201-204 (2016)
Background: Congenital myopathies (CMs) though considered distinct disorders, simultaneous occurrence of central nucleus, nemaline rods, and cores in the same biopsy are scarcely reported. Objective: A retrospective reassessment of cases diagnosed as
Externí odkaz:
https://doaj.org/article/f310c8a57706457f847b7cf20d154000
Autor:
Amanda Hoffman, Xiaotong Wu, Jianjie Wang, Amanda Brodeur, Rintu Thomas, Ravindra Thakkar, Halena Hadi, Garry P. Glaspell, Molly Duszynski, Adam Wanekaya, Robert K. DeLong
Publikováno v:
Materials, Vol 10, Iss 12, p 1430 (2017)
Two-dimensional fluorescence difference spectroscopy (2-D FDS) was used to determine the unique spectral signatures of zinc oxide (ZnO), magnesium oxide (MgO), and 5% magnesium zinc oxide nanocomposite (5% Mg/ZnO) and was then used to demonstrate the
Externí odkaz:
https://doaj.org/article/e4adb86f4ae64ef58bb162908d3a6ae0
Publikováno v:
RSC Medicinal Chemistry. 14:658-670
A cyclic peptide targeted to the immune checkpoint protein CTLA4 is designed using a hierarchy of computational methods, demonstrated to bind by a physical measurement, and shown to inhibit tumor growth in cell culture and in mice.
Publikováno v:
Nanoscale Advances. 4:1741-1757
Ordered nanoscale patterns have been observed by atomic force microscopy at graphene-water and graphite-water interfaces. The two dominant explanations for these patterns are that (i) they consist of self-assembled organic contaminants or (ii) they a
Autor:
Ravindra Thakkar, Jeffrey Comer
This data set for the manuscript entitled "Computational Design of a Cyclic Peptide that Inhibits the CTLA4 Immune Checkpoint Pathway" includes all files needed to run and analyze the simulations of a designed cyclic peptide (Peptide 16) bound to CTL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::386585126e5d1cf89b0c35c85798c50a