o-Iodoxybenzoic Acid MediatedN-Arylation of Aromatic Amines by Using Arylhydrazines as the Arylating Counterpart

Autor: Ravindra R. Jadhav, Krishnacharya G. Akamanchi, Sameerana N. Huddar

Publikováno v: European Journal of Organic Chemistry. 2013:6779-6783

Through free-radical trapping experiments we have established, for the first time, the combination of arylhydrazines with o-iodoxybenzoic acid (IBX) for the generation of aryl free radicals. On the basis of this finding, a method was developed for th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de1b13785b5b9e40a3da90b342cfcc70
https://doi.org/10.1002/ejoc.201300917

Molecular Iodine in Aqueous Ammonia: Oxidative Fragmentation of Oxiranes to Nitriles

Autor: Ravindra R. Jadhav, Krishnacharya G. Akamanchi

Publikováno v: Chemistry Letters. 42:162-164

Oxiranes undergo oxidative fragmentation, when treated with iodine in aqueous ammonia, to give nitriles. The reaction goes via formation of 1,2-amino alcohols as intermediates followed by C–C bond ...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d27093e81dd4e6419496bea3e53b4d5
https://doi.org/10.1246/cl.2013.162

ChemInform Abstract: Molecular Iodine in Aqueous Ammonia: Oxidative Fragmentation of Oxiranes to Nitriles

Autor: Ravindra R. Jadhav, Krishnacharya G. Akamanchi

Publikováno v: ChemInform. 44

A new, more convenient, and cost-effective method for the oxidative C—C fragmentation of oxiranes to nitriles using nonexplosive molecular iodine is developed.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::03b69fe03c7f6e140047494325fd8f66
https://doi.org/10.1002/chin.201328078

ChemInform Abstract: Oxidative Fragmentation of Oxiranes to Nitriles with Hypervalent Iodine(V) Reagents in Aqueous Ammonia

Autor: Swapnil S. Deshmukh, Ravindra R. Jadhav, Sameerana N. Huddar, Krishnacharya G. Akamanchi

Publikováno v: ChemInform. 42

Nucleophilic ring-opening of the starting epoxides with aqueous ammonia followed by oxidation of the intermediate amino alcohol with IBX results in formation of the corresponding nitriles.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dc7b05f0b48bf1b2baea2f37ce56e8b3
https://doi.org/10.1002/chin.201146063

A Preclinical Candidate Targeting Mycobacterium tuberculosis KasA.

Autor: Inoyama D; Department of Pharmacology, Physiology, and Neuroscience, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Awasthi D; Department of Pharmacology, Physiology, and Neuroscience, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Capodagli GC; Department of Microbiology, Biochemistry and Molecular Genetics, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, USA., Tsotetsi K; Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenco Center for the Study of Emerging and Re-emerging Pathogens, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Sukheja P; Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenco Center for the Study of Emerging and Re-emerging Pathogens, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Zimmerman M; Public Health Research Institute, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Li SG; Department of Pharmacology, Physiology, and Neuroscience, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Jadhav R; Department of Pharmacology, Physiology, and Neuroscience, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Russo R; Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenco Center for the Study of Emerging and Re-emerging Pathogens, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Wang X; Department of Pharmacology, Physiology, and Neuroscience, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Grady C; Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenco Center for the Study of Emerging and Re-emerging Pathogens, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Richmann T; Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenco Center for the Study of Emerging and Re-emerging Pathogens, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Shrestha R; Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenco Center for the Study of Emerging and Re-emerging Pathogens, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Li L; Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenco Center for the Study of Emerging and Re-emerging Pathogens, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Ahn YM; Department of Pharmacology, Physiology, and Neuroscience, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Ho Liang HP; Public Health Research Institute, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Mina M; Public Health Research Institute, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Park S; Public Health Research Institute, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Perlin DS; Public Health Research Institute, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Connell N; Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenco Center for the Study of Emerging and Re-emerging Pathogens, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Dartois V; Public Health Research Institute, Rutgers University - New Jersey Medical School, Newark, NJ, USA., Alland D; Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenco Center for the Study of Emerging and Re-emerging Pathogens, Rutgers University - New Jersey Medical School, Newark, NJ, USA. Electronic address: allandda@njms.rutgers.edu., Neiditch MB; Department of Microbiology, Biochemistry and Molecular Genetics, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, USA. Electronic address: neiditmb@njms.rutgers.edu., Kumar P; Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenco Center for the Study of Emerging and Re-emerging Pathogens, Rutgers University - New Jersey Medical School, Newark, NJ, USA. Electronic address: kumarp3@njms.rutgers.edu., Freundlich JS; Department of Pharmacology, Physiology, and Neuroscience, Rutgers University - New Jersey Medical School, Newark, NJ, USA; Division of Infectious Disease, Department of Medicine and the Ruy V. Lourenco Center for the Study of Emerging and Re-emerging Pathogens, Rutgers University - New Jersey Medical School, Newark, NJ, USA. Electronic address: freundjs@rutgers.edu.

Publikováno v: Cell chemical biology [Cell Chem Biol] 2020 May 21; Vol. 27 (5), pp. 560-570.e10. Date of Electronic Publication: 2020 Mar 19.