Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ravindra K, Hajela"'
Publikováno v:
Muscle & Nerve. 51:176-184
Introduction: Lambert–Eaton myasthenic syndrome (LEMS) is an autoimmune presynaptic neuromuscular disorder. Autoantibodies against subunits of voltage-gated calcium channels (VGCCs) associated with acetylcholine release are thought to cause LEMS. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80ba8eb877445f3a3ed8873209970db1
https://doi.org/10.1002/mus.24295
https://doi.org/10.1002/mus.24295
Early onset effects of methylmercury (MeHg) on recombinant α1β2γ2S or α6β2γ2S subunit-containing GABAA receptors were examined. These are two of the most prevalent receptor types found in cerebellum-a consistent target of MeHg-induced neurotoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1093fdf691d8705da9e851b9c508de27
https://europepmc.org/articles/PMC5726768/
https://europepmc.org/articles/PMC5726768/
Autor:
Frank O. Johnson, William D. Atchison, Dawn M. Parsell, Yukun Yuan, Ravindra K. Hajela, Alisha Chitrakar
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 338:518-527
Mice expressing the human Cu(2+)/Zn(2+) superoxide dismutase 1 (hSOD1) gene mutation (hSOD1(G93A); G93A) were exposed to methylmercury (MeHg) at concentrations that did not cause overt motor dysfunction. We hypothesized that low concentrations of MeH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13f0cd815fdba3960762d475d2ebec4c
https://doi.org/10.1124/jpet.110.174466
https://doi.org/10.1124/jpet.110.174466
Autor:
Shuangqing Peng, Qianqian Li, Gang Han, Zhi-Guo Sheng, Ravindra K. Hajela, Yan-Sheng Dong, Chang-yong Wang, Mi-feng Liu, Yi-Mei Wang, Hong-bo Li
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 322:155-165
Quinolone(s) (QNs) is widely used in infection therapy due to its good antimicrobial characteristics. However, QNs-induced arthropathy of immature animals has led to restrictions on the therapeutic use of these antimicrobial agents. The exact mechani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db308b6d635b1709d8c086702b9c737d
https://doi.org/10.1124/jpet.106.118224
https://doi.org/10.1124/jpet.106.118224
Publikováno v:
Brain Research. 1045:116-123
Mechanical forces can alter the gating of several kinds of ion channels in many types of cells, but the mechanisms underlying the mechanosensitivity are not clearly understood. To date, there are very few reports on mechanosensitivity of Ca2+ channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e20935a4d8f896a079865182eb08ded
https://doi.org/10.1016/j.brainres.2005.03.039
https://doi.org/10.1016/j.brainres.2005.03.039
Publikováno v:
Phytoprotection. 72:1-13
Cet article de synthèse présente une revue des recherches concernant les interactions moléculaires et cellulaires de la maladie hollandaise de l'orme. Cette maladie, causée par le champignon Ophiostoma ulmi, provoque un flétrissement vasculaire
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8dbf1bb80ed253a5b651d583d0c707f
https://doi.org/10.7202/705997ar
https://doi.org/10.7202/705997ar
Publikováno v:
Molecular Pharmacology. 62:1418-1430
Lead (Pb(2+)) is a well-known inhibitor of voltage-dependent Ca(2+) channels in their native environments in several types of cells. However, its effects on discrete Ca(2+) channel phenotypes in isolation have not been well studied. We compared how s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::824c58bf5489847d601b425a76ea5ccf
https://doi.org/10.1124/mol.62.6.1418
https://doi.org/10.1124/mol.62.6.1418
Publikováno v:
Journal of Neurochemistry. 64:1245-1251
Lambert-Eaton myasthenic syndrome (LEMS) is an autoimmune neuromuscular disease in which impairment of Ca 2+ entry into the nerve ending and consequent impaired release of acetylcholine (ACh) results in muscle weakness. The identity of the primary an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c562920a5649efb7edc1c976fed86c7
https://doi.org/10.1046/j.1471-4159.1995.64031245.x
https://doi.org/10.1046/j.1471-4159.1995.64031245.x
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 302:424-432
Methylmercury (MeHg) disrupts the function of native, high voltage-activated neuronal Ca(2+) channels in several types of cells. However, the effects of MeHg on isolated Ca(2+) channel phenotypes have not been examined. The aim of the present study w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d828a8c5feaa299c09af95f5a1aabb8a
https://doi.org/10.1124/jpet.102.032748
https://doi.org/10.1124/jpet.102.032748
Autor:
Ravindra K. Hajela, Mariam B. Sticklen, Joseph M. Vargas, Donald Warkentin, Benli Chai, David Green, Shahina B. Maqbool, Robab Sabzikar
Publikováno v:
Plant Science. 163:183-193
We isolated a cDNA clone ( hs2 ) encoding a chitinase-like protein from a triploid Dutch elm disease resistant American elm ( Ulmus americana NPS-3-487). Amino acid sequence of this chitinase-like protein showed 65–78% homology to other plant chiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::009fe9f2cea1c2dc52b08bf4522a6ec9
https://doi.org/10.1016/s0168-9452(02)00069-9
https://doi.org/10.1016/s0168-9452(02)00069-9