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pro vyhledávání: '"Ravindra Gavhane"'
Autor:
Madhu bala, Partha P. Mukhopadhyay, Kasim A. Mookhtiar, Bheemashankar Kulkarni, Nadim S. Shaikh, Amol A. Raje, Dhananjay N. Umrani, Debnath Bhuniya, Prasad Sherkar, Yogesh Munot, Sachin Joshi, Satyanarayan Reddy, Vishwottam Kandikere, Mahendra Lohote, Jitesh P. Iyer, Vijay Jamdar, Rajkanth Petla, Ranganayaki Nagaraj, Ravindra Gavhane, Ashwinkumar V. Meru, Sreekanth R. Rouduri
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:2208-2217
Targeting nuclear receptor RORγ is recognized to be beneficial in multiple autoimmune disorders. We disclosed new indole analogues as potent RORγ inverse agonists. RO-2 as one of the potent and orally bioavailable compounds was evaluated in various