Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ravindra Dattatraya Gupte"'
Autor:
Ravindra Dattatraya Gupte, Mahesh G. Jadhav, Prabhu Dutt Mishra, Asha Kulkarni-Almeida, Bindu Hegde, Shruta Dadarkar, Meet Shah, Girish B Mahajan, Nilesh M Dagia, Jacqueline Trivedi
Publikováno v:
International Immunopharmacology. 33:63-69
Rheumatoid arthritis (RA), an autoimmune-inflammatory disease is characterized by dysregulation of signal transduction pathways, increased production of pro-inflammatory cytokines, enhanced leukocyte infiltration into synovial microvascular endotheli
Autor:
Sufyan G. Sayyed, Rathinasabapathy Anandharajan, Muralidhara Padigaru, Anagha Damre, Prakash G. Chandak, Ravindra Dattatraya Gupte, Amol Dixit, Manoja K. Brahma, Somesh Sharma, Kumar V.S. Nemmani, Jaspreet Suthar, Nitin J. Deshmukh, Lalit S. Doshi, Pooja Dixit
Publikováno v:
Metabolism. 58:1503-1516
Insulin resistance is central to the pathogenesis of type 2 diabetes mellitus. Previous studies have demonstrated that compounds that cause adipogenesis and improve glucose uptake in 3T3-L1 cells are potential insulin sensitizers. Therefore, we evalu
Autor:
Sanjay Kumar, Lyle C. Fonseca, Nilesh M. Dagia, Mahesh G. Jadhav, Shruta S. Dadarkar, Asha Kulkarni-Almeida, Ravindra Dattatraya Gupte, Mandar R. Bhonde, Anshu Chetrapal-Kunwar, Divya V. Kamath, Gautam Agarwal, Firuza Kharas, Jacqueline Trivedi
Publikováno v:
American journal of physiology. Cell physiology. 298(4)
A promising therapeutic approach to diminish pathological inflammation is to inhibit the increased production and/or biological activity of proinflammatory cytokines (e.g., TNF-alpha, IL-6). The production of proinflammatory cytokines is controlled a
Autor:
Vijaykumar Deore, Shruta S. Dadarkar, Pooja Bhatt, Dimple Bhatia, Kumar V.S. Nemmani, Nilesh M. Dagia, Sanjay Kumar, Mandar R. Bhonde, Abhijit Roychowdhury, Ravindra Dattatraya Gupte, Nilambari Yewalkar, Somesh Sharma, Nikesh Desai, Mahesh G. Jadhav, Ram A. Vishwakarma, Aditi Amol Tannu
Publikováno v:
Bioorganicmedicinal chemistry letters. 19(11)
A series of novel cyanopyridyl based molecules ( 1 – 14 ) were designed, synthesized and probed for inhibition of mammalian target of rapamycin (mTOR) activity. Compound 14 was found to be a potent inhibitor of mTOR activity as assessed by enzyme-l
Autor:
Pooja Bhatt, Ravindra Dattatraya Gupte, Chandrika B-Rao, Pradip K. Gadekar, Santosh S. Parkale, Sarala Balachandran, Nilesh M. Dagia, Divya V. Kamath, Shaila Srinivasan, Anshu Chetrapal-Kunwar, Koteppa Pari, Julie Bose, Gautam Agarwal, Shruta S. Dadarkar, Somesh Sharma, Noopur Mandrekar, Ram A. Vishwakarma, Atish Rodge, Lyle C. Fonseca
Publikováno v:
European journal of pharmacology. 607(1-3)
A promising therapeutic approach to diminish pathological inflammation is to inhibit the synthesis and/or biological activity of macrophage migration inhibitory factor (MIF). Prior studies have shown that intraperitoneal administration of small-molec
Autor:
Sanjay Kumar, Somesh Sharma, Nilesh M Dagia, Dimple Bhatia, Aditi Amol Tannu, Ram A. Vishwakarma, Mahesh G. Jadhav, Nilambari Yewalkar, Shruta Dadarkar, Vijaykumar Deore, Nikesh Desai, Pooja Bhatt, Ravindra Dattatraya Gupte, Mandar R. Bhonde
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 295(6)
Ulcerative colitis is an autoimmune-inflammatory disease characterized by increased proliferation of colonic epithelial cells, dysregulation of signal transduction pathways, elevated mucosal T cell activation, increased production of proinflammatory
Autor:
Ram A. Vishwakarma, Ravindra Dattatraya Gupte, Mandar R. Bhonde, Nilesh M. Dagia, Somesh Sharma, Sanjay Kumar
Publikováno v:
American Journal of Gastroenterology. 103:S408-S409