Zobrazeno 1 - 10
of 227
pro vyhledávání: '"Ravinder K. Gill"'
Autor:
Nathan Calzadilla, Dulari Jayawardena, Aisha Qazi, Anchal Sharma, Kai Mongan, Shane Comiskey, Abhijith Eathara, Seema Saksena, Pradeep K. Dudeja, Waddah A. Alrefai, Ravinder K. Gill
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 8, p 4459 (2024)
Serotonin transporter (SERT) deficiency has been implicated in metabolic syndrome, intestinal inflammation, and microbial dysbiosis. Interestingly, changes in microbiome metabolic capacity and several alterations in host gene expression, including li
Externí odkaz:
https://doaj.org/article/5733400260834f1ba7ce8d7860227f13
Autor:
Aisha Qazi, Shane Comiskey, Nathan Calzadilla, Fatimah Amin, Anchal Sharma, Ei Khin, Nathaniel Holton, Christopher R. Weber, Seema Saksena, Anoop Kumar, Waddah A. Alrefai, Ravinder K. Gill
Publikováno v:
Nutrients, Vol 15, Iss 23, p 4980 (2023)
Diet–microbiota interactions are emerging as important contributors in the pathogenesis of inflammatory bowel diseases (IBD), characterized by chronic inflammation of the GI tract. The aryl hydrocarbon receptor (AhR) transcription factor regulates
Externí odkaz:
https://doaj.org/article/e6160aa74cb747fd927593964e1c2b3e
Autor:
Nathan Calzadilla, Aisha Qazi, Anchal Sharma, Kai Mongan, Shane Comiskey, Jahnavi Manne, Alvin G. Youkhana, Sonam Khanna, Seema Saksena, Pradeep K. Dudeja, Waddah A. Alrefai, Ravinder K. Gill
Publikováno v:
Metabolites, Vol 13, Iss 7, p 873 (2023)
Inflammatory bowel diseases (IBD) involve complex interactions among genetic factors, aberrant immune activation, and gut microbial dysbiosis. While metabolomic studies have focused on feces and serum, fewer investigations have examined the intestina
Externí odkaz:
https://doaj.org/article/2af492034a3b4e5f95200b70bdaff62a
Autor:
Nathan Calzadilla, Shane M. Comiskey, Pradeep K. Dudeja, Seema Saksena, Ravinder K. Gill, Waddah A. Alrefai
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Bile acids are critical for the digestion and absorption of lipids and fat-soluble vitamins; however, evidence continues to emerge supporting additional roles for bile acids as signaling molecules. After they are synthesized from cholesterol in the l
Externí odkaz:
https://doaj.org/article/e8ac3e75f2a24f048581673479c81cea
Autor:
Christopher R. Manzella, Max Ackerman, Megha Singhal, Alexander L. Ticho, Justin Ceh, Waddah A. Alrefai, Seema Saksena, Pradeep K. Dudeja, Ravinder K. Gill
Publikováno v:
Cellular Physiology and Biochemistry, Vol 54, Iss 1, Pp 126-141 (2020)
Externí odkaz:
https://doaj.org/article/8e41b12155e94945a0945bf4fc245d2f
Publikováno v:
Liver Research, Vol 3, Iss 1, Pp 31-39 (2019)
Bile acids modulate several gastrointestinal (GI) functions including electrolyte secretion and absorption, gastric emptying, and small intestinal and colonic motility. High concentrations of bile acids lead to diarrhea and are implicated in the deve
Externí odkaz:
https://doaj.org/article/bca3174a44ae41b7b91b4324b84a0c38
Publikováno v:
Frontiers in Medicine, Vol 7 (2020)
Non-alcoholic fatty liver disease (NAFLD) is a major health problem associated with obesity and other features of the metabolic syndrome including insulin resistance and dyslipidemia. The accumulation of lipids in hepatocytes causes liver damage and
Externí odkaz:
https://doaj.org/article/472fa33d823f431596b51e951588d65d
Publikováno v:
F1000Research, Vol 8 (2019)
Microvillus inclusion disease (MVID) is a rare congenital severe malabsorptive and secretory diarrheal disease characterized by blunted or absent microvilli with accumulation of secretory granules and inclusion bodies in enterocytes. The typical clin
Externí odkaz:
https://doaj.org/article/30c470a04b8248a78935296cf6913526
Autor:
Christopher Manzella, Megha Singhal, Waddah A. Alrefai, Seema Saksena, Pradeep K. Dudeja, Ravinder K. Gill
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract Aryl hydrocarbon receptor (AhR) is a nuclear receptor that controls xenobiotic detoxification via induction of cytochrome P450 1A1 (CYP1A1) and regulates immune responses in the intestine. Metabolites of L-tryptophan activate AhR, which conf
Externí odkaz:
https://doaj.org/article/519824b2f4d143929624a61385e070f6
Autor:
Arivarasu N. Anbazhagan, Shubha Priyamvada, Anoop Kumar, Dulari Jayawardena, Alip Borthakur, Ravinder K. Gill, Waddah A. Alrefai, Pradeep K. Dudeja, Seema Saksena
Publikováno v:
American Journal of Physiology-Cell Physiology. 323:C1720-C1727
Na+/H+ exchanger-3 (NHE-3) is the major apical membrane transporter involved in vectorial Na+ absorption in the intestine. Dysregulation of NHE-3 expression and/or function has been implicated in pathophysiology of diarrhea associated with gut inflam