Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Ravinder Abrol"'
Autor:
Manae Tatsumi, Christian Cruz, Nozomi Kamakura, Riku Kuwabara, Gaku Nakamura, Tatsuya Ikuta, Ravinder Abrol, Asuka Inoue
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract G-protein-coupled receptors (GPCRs) transduce diverse signals into the cell by coupling to one or several Gα subtypes. Of the 16 Gα subtypes in human cells, Gα12 and Gα13 belong to the G12 subfamily and are reported to be functionally di
Externí odkaz:
https://doaj.org/article/ea2e846a28764393a220c1f4ee76a980
Autor:
Richard T. Waldron, Hsin-Yuan Su, Honit Piplani, Joseph Capri, Whitaker Cohn, Julian P. Whitelegge, Kym F. Faull, Sugunadevi Sakkiah, Ravinder Abrol, Wei Yang, Bo Zhou, Michael R. Freeman, Stephen J. Pandol, Aurelia Lugea
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 4, Pp 479-497 (2018)
Background & Aims: Heavy alcohol drinking is associated with pancreatitis, whereas moderate intake lowers the risk. Mice fed ethanol long term show no pancreas damage unless adaptive/protective responses mediating proteostasis are disrupted. Pancreat
Externí odkaz:
https://doaj.org/article/3fb25426f99449cf82738f6cbeb12ac8
Autor:
Bingchen Han, Ying Qu, Yanli Jin, Yi Yu, Nan Deng, Kolja Wawrowsky, Xiao Zhang, Na Li, Shikha Bose, Qiang Wang, Sugunadevi Sakkiah, Ravinder Abrol, Tor W. Jensen, Benjamin P. Berman, Hisashi Tanaka, Jeffrey Johnson, Bowen Gao, Jijun Hao, Zhenqiu Liu, Ralph Buttyan, Partha S. Ray, Mien-Chie Hung, Armando E. Giuliano, Xiaojiang Cui
Publikováno v:
Cell Reports, Vol 13, Iss 5, Pp 1046-1058 (2015)
The mesoderm- and epithelial-mesenchymal transition-associated transcription factor FOXC1 is specifically overexpressed in basal-like breast cancer (BLBC), but its biochemical function is not understood. Here, we demonstrate that FOXC1 controls cance
Externí odkaz:
https://doaj.org/article/2f476aea81b34e19b5381ab1d419696a
Publikováno v:
PLoS Computational Biology, Vol 12, Iss 3, p e1004805 (2016)
The understanding of G-protein coupled receptors (GPCRs) is undergoing a revolution due to increased information about their signaling and the experimental determination of structures for more than 25 receptors. The availability of at least one recep
Externí odkaz:
https://doaj.org/article/9f77d80ff7984a75a07d4091e7d53029
Autor:
Bridget-K. Kawamala, Ravinder Abrol
Publikováno v:
Biochemical and Biophysical Research Communications. 624:1-7
Integral membrane proteins (MPs) are dominated by transmembrane α-helical (TMH) proteins playing critical roles in cellular signaling processes. These proteins display a wide range of sizes from one TMH domain to at least 26 TMH domains and diverse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7572ac9a1a379415110d89860ac2f8fd
https://doi.org/10.1016/j.bbrc.2022.07.006
https://doi.org/10.1016/j.bbrc.2022.07.006
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1902d35f56513a58f9717c277ab1fdc2
https://doi.org/10.1096/fasebj.2022.36.s1.r5854
https://doi.org/10.1096/fasebj.2022.36.s1.r5854
Publikováno v:
Journal of Molecular Evolution
The polytopic helical membrane proteome is dominated by proteins containing seven transmembrane helices (7TMHs). They cannot be grouped under a monolithic fold or superfold. However, a parallel structural analysis of folds around that magic number of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b25b8c53ea0bee2f104c60eccc3a6b5b
http://europepmc.org/articles/PMC7162841
http://europepmc.org/articles/PMC7162841
Publikováno v:
Advances in protein chemistry and structural biology. 128
G protein-coupled receptors (GPCRs) make up the largest superfamily of integral membrane proteins and play critical signal transduction roles in many physiological processes. Developments in molecular biology, biophysical, biochemical, pharmacologica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f646282e5521f57bbafa875e18664822
https://pubmed.ncbi.nlm.nih.gov/35034722
https://pubmed.ncbi.nlm.nih.gov/35034722
Autor:
Felix Alonso-Valenteen, Sam Sances, HongQiang Wang, Simoun Mikhael, Jessica Sims, Michael Taguiam, Dustin Srini, Romny Sanchez, Erik Serrano, Briana Ondatje, James Teh, Michelle Wong, Kimngan Nguyenle, Tianxin Miao, Rebecca Benhaghnazar, John Yu, Clive Svendsen, Ravinder Abrol, Lali Medina Kauwe
Triple-negative breast cancer (TNBC) lacks selective biomarkers targeted by current clinical therapies and often metastasizes to the brain. Crossing the blood-brain barrier (BBB) and reaching intracranial tumors is a clinical challenge contributing t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f801e85817e58c7817c294e6af8cfebe
https://doi.org/10.21203/rs.3.rs-1139650/v1
https://doi.org/10.21203/rs.3.rs-1139650/v1
Publikováno v:
Membrane Proteins ISBN: 9780323988957
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c896eb7865ff34cf9ee27b0e2a65bb0f
https://doi.org/10.1016/bs.apcsb.2021.11.001
https://doi.org/10.1016/bs.apcsb.2021.11.001