Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ravinder Sardana"'
Publikováno v:
Pharmaceutical Biology. 46:72-81
The pharmacological activity of neuroactive phytochemicals on recombinant human glutamic acid decarboxylase 65 (hGAD65) was investigated. GAD catalyzes the conversion of glutamic acid to γ-aminobutyric acid (GABA), which acts as an important inhibit
Publikováno v:
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 144:94-100
Glutamic acid decarboxylase (GAD) catalyzes the conversion of glutamate to γ-aminobutyric acid (GABA) that acts as an important inhibitory neurotransmitter in the vertebrate brain, as well as in the regulation of neuroendocrine function. GAD65 and G
Autor:
David Dekoeyer, Sharon Regan, Charlotte Rothwell, Barry S. Flinn, Martin Lagüe, Gefu Wang-Pruski, Claudia Goyer, Ravinder Sardana, Rebecca Griffiths, Xiu-Qing Li, Patrice Audy
Publikováno v:
Plant Molecular Biology. 59:407-433
To help develop an understanding of the genes that govern the developmental characteristics of the potato (Solanum tuberosum), as well as the genes associated with responses to specified pathogens and storage conditions, The Canadian Potato Genome Pr
Autor:
Illimar Altosaar, Jelica Mehic, Fiona A. Prior, Suzanne Porter, Margaret Bell, Monika Tocchi, Peter R. Ganz, Ravinder Sardana, Eilleen S. Tackaberry, Anil K. Dudani
Publikováno v:
Genome. 46:521-526
The use of transgenic plants in the production of recombinant proteins for human therapy, including subunit vaccines, is being investigated to evaluate the efficacy and safety of these emerging biopharmaceutical products. We have previously shown tha
Autor:
Maximilian Callaghan, Xiongying Cheng, Ravinder Sardana, Mitra Panahi, Jenny Phipps, Zaman Alli, Illimar Altosaar
Publikováno v:
Molecular Breeding. 12:21-31
The potential of plant expression systems to produce functional recombinant proteins was used to produce human prohormone insulin-like growth factor-1B (pro-IGF-1B). Insulin-like growth factor-1 (IGF-1) plays a role in normal growth, development and
Autor:
Suzanne Porter, Illimar Altosaar, Peter R. Ganz, Anton Andonov, Anil K. Dudani, Ravinder Sardana, Zaman Alli, Laurian S. Robert, Béatrice Pierre, Johann Schernthaner, Eilleen S. Tackaberry
Publikováno v:
Phytochemistry Reviews. 1:55-66
A plant based high fidelity vaccine production system is being developed with emphasis on producing antigens capable of being orally delivered in multivalent or subunit plant packets. Plant-based edible vaccines may provide an attractive, safe and in
Autor:
Anil K. Dudani, Illimar Altosaar, Muthukrishnan Narayanan, Eilleen S. Tackaberry, Peter R. Ganz, Ravinder Sardana, Zaman Alli, Mitra Panahi
Publikováno v:
Transgenic Research. 11:521-531
Human granulocyte-macrophage colony stimulating factor (GM-CSF), a cytokine with many applications in clinical medicine, was produced specifically in the seeds of transgenic tobacco plants. Two rice endosperm-specific glutelin promoters of different
Autor:
Fiona A. Prior, Peter R. Ganz, Eilleen S. Tackaberry, K. E. Wright, Ravinder Sardana, Illimar Altosaar, Anil K. Dudani
Publikováno v:
Transgenic Research. 10:177-181
As part of ongoing studies into the use of plant expression systems for making human therapeutic proteins, we have successfully expressed the major glycoprotein, gB, of human cytomegalovirus (HCMV) in transgenic tobacco plants. Viral glycoprotein was
Autor:
Youbin Xiang, Illimar Altosaar, Qingyao Shu, Mingwei Gao, Cui Hu, Yingwu Xia, Xiongying Cheng, Ravinder Sardana, Dianxing Wu, Hairui Cui, Gongyin Ye
Publikováno v:
Molecular Breeding. 6:433-439
To fully explore the resistance potential of transgenic rice produced by Agrobacterium-mediated transformation, an elite line KMD1 was assessed for its resistance to eight lepidopteran rice pest species. KMD1 contained a synthetic cry1Ab gene from Ba
Autor:
Illimar Altosaar, P. R. Ganz, A. K. Dudani, Fiona A. Prior, Ravinder Sardana, Eilleen S. Tackaberry, M Tocchi
Publikováno v:
Vaccine. 17:3020-3029
Plant seeds offer unique opportunities for the production and delivery of oral subunit vaccines. We have used the immunodominant glycoprotein B complex of human cytomegalovirus (HCMV), introduced into tobacco plants, as a model system for studying th