Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ravichandran N Murugan"'
Autor:
Ravichandran N Murugan, Mija Ahn, Woo Cheol Lee, Hye-Yeon Kim, Jung Hyun Song, Chaejoon Cheong, Eunha Hwang, Ji-Hyung Seo, Song Yub Shin, Sun Ho Choi, Jung-Eun Park, Jeong Kyu Bang
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80043 (2013)
BACKGROUND: Over the years, a great deal of effort has been focused on the design and synthesis of potent, linear peptide inhibitors targeting the polo-like kinase 1 (Plk1), which is critically involved in multiple mitotic processes and has been esta
Externí odkaz:
https://doaj.org/article/1449daaa999240f594f033e6bd3bdfa2
Autor:
Ravichandran N Murugan, Binu Jacob, Mija Ahn, Eunha Hwang, Hoik Sohn, Hyo-Nam Park, Eunjung Lee, Ji-Hyung Seo, Chaejoon Cheong, Ky-Youb Nam, Jae-Kyung Hyun, Ki-Woong Jeong, Yangmee Kim, Song Yub Shin, Jeong Kyu Bang
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80025 (2013)
BACKGROUND: Much attention has been focused on the design and synthesis of potent, cationic antimicrobial peptides (AMPs) that possess both antimicrobial and anti-inflammatory activities. However, their development into therapeutic agents has been li
Externí odkaz:
https://doaj.org/article/f3a8b3ccce4f4534a7014ee4372678ec
Autor:
Kyung S. Lee, Shinobu Komiya, Mija Ahn, Nam Kim, Bonsu Ku, Tae Sung Kim, Suk Youl Park, Seung Jun Kim, Jung-Eun Park, Ju Hee Kim, Jeong K. Bang, Ki Won Lee, Byung-Ha Oh, Wei Yang, Lan Tian, Raymond L. Erikson, Bo Yeon Kim, Mi Jeong Kwak, Hironobu Hojo, Ravichandran N. Murugan
Publikováno v:
Nature structural & molecular biology
Polo-like kinase 4 (Plk4) is a key regulator of centriole duplication, an event critical for the maintenance of genomic integrity. Here we showed that Plk4 relocalizes from the inner Cep192 ring to the outer Cep152 ring as newly recruited Cep152 asse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39169a8e98481c79adbf14b33483b2ee
https://doi.org/10.1038/nsmb.2846
https://doi.org/10.1038/nsmb.2846
Autor:
Hun Yeong Koh, Ravichandran N. Murugan, Woo Kyu Park, Ju Myung Kwak, Jae Yang Gong, Ji Soo Moon, Hee-Yoon Lee, Jea I Choi
Publikováno v:
Bulletin of the Korean Chemical Society. 34:3467-3470
In this study, a new library of1,2,3-triazole arylpiperazine derivatives, possessing propylor butyl carbon chains in between arylpiperazine and 1,2,3-triazole moieties, were designed and synthesized in an effortto further understand the structure-act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8c81dea48413ad8b589c7b8a66f5511
https://doi.org/10.5012/bkcs.2013.34.11.3467
https://doi.org/10.5012/bkcs.2013.34.11.3467
Autor:
Hak Jun Kim, Eun Jung Kim, Jeong Kyu Bang, Song Yub Shin, Mija Ahn, Jun Hyuck Lee, Ravichandran N. Murugan
Publikováno v:
Bulletin of the Korean Chemical Society. 33:3565-3570
Department of Polar Sciences, University of Science and Technology, Incheon 406-840, KoreaReceived July 26, 2012, Accepted August 13, 2012Until now, few groups reported the antifreeze activity of cyclic glycopeptides; however, the tedious syntheticpr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9992540ee123f1425dc4386819a54fa
https://doi.org/10.5012/bkcs.2012.33.11.3565
https://doi.org/10.5012/bkcs.2012.33.11.3565
Autor:
Ravichandran N. Murugan, Mija Ahn, Song Yub Shin, Chaejoon Cheong, Hak Jun Kim, Jeong Kyu Bang, Eun Jung Kim, Shin Won Kang, Hee Jung Park, Jun Hyuck Lee
Publikováno v:
Bulletin of the Korean Chemical Society. 33:2411-2414
Department of Polar Sciences, University of Science and Technology, Incheon 406-840, KoreaReceived February 29, 2012, Accepted April 2, 2012Key Words : Antifreeze glycoproteins (AFGPs), Thermal hysteresis activity, Ice morphology, Hexagonal bi-pyrami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0342daed1cfbadf0c60da5b6085afd6d
https://doi.org/10.5012/bkcs.2012.33.7.2411
https://doi.org/10.5012/bkcs.2012.33.7.2411
Autor:
Jeong Kyu Bang, Hoik Sohn, Eun Kyoung Ryu, Ravichandran N. Murugan, Yong Hai Nan, Chaejoon Cheong, Mija Ahn, Eunha Hwang, Eunhee Kim, Shin Won Kang, Song Yub Shin
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 21:6148-6153
One of the obvious disadvantages of natural peptides is their liability to proteases. Among the several solutions for this issue, peptoids or oligomers of N-substituted glycine have emerged as a promising tool that may enhance the stability of proteo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89177106b8055314a3309c63ecbc3cc2
https://doi.org/10.1016/j.bmcl.2011.08.012
https://doi.org/10.1016/j.bmcl.2011.08.012
Autor:
Yong Hai Nan, Eunhee Kim, Eun-Joo Kim, Chaejoon Cheong, Shin-Won Kang, Hoik Sohn, Jeong-Kyu Bang, Song-Yub Shin, Eun-Kyoung Ryu, Ravichandran N. Murugan, Mija Ahn
Publikováno v:
Bulletin of the Korean Chemical Society. 32:3327-3332
Antimicrobial peptides have recently gained the much attention because of their ability to make defense system from attacking bacterial infections. Drosocin has been considered as very attractive antibiotic agents because of low toxicity against huma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84809ae0b83711546efb6ae96eccafea
https://doi.org/10.5012/bkcs.2011.32.9.3327
https://doi.org/10.5012/bkcs.2011.32.9.3327
Autor:
Jung-Eun Park, Song Yub Shin, Chaejoon Cheong, Ravichandran N. Murugan, Eun-Hee Kim, Jeong Kyu Bang, Kyung S. Lee
Publikováno v:
Molecules and Cells. 32:209-220
Members of polo-like kinases (collectively, Plks) have been identified in various eukaryotic organisms and play pivotal roles in cell proliferation. They are characterized by the presence of a distinct region of homology in the C-terminal noncatalyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::185b27f96675d4aa9d4ada4eddc47acc
https://doi.org/10.1007/s10059-011-0126-3
https://doi.org/10.1007/s10059-011-0126-3
Publikováno v:
European Journal of Organic Chemistry. 2009:5028-5037
Stereoselective epoxidation of [4.3.3]propellane 16 set the stage for the Lewis acid catalyzed stereospecific ring contraction to an oxygenated modhephene structure and eventually led to the total synthesis of (–)-13-acetoxymodhephene and (+)-14-ac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3bac05ac95e4f38595c447e93e25a5f3
https://doi.org/10.1002/ejoc.200900713
https://doi.org/10.1002/ejoc.200900713