Zobrazeno 1 - 10
of 240
pro vyhledávání: '"Ravichandran, Ramasamy"'
Autor:
Gautham Yepuri, Lisa M. Ramirez, Gregory G. Theophall, Sergei V. Reverdatto, Nosirudeen Quadri, Syed Nurul Hasan, Lei Bu, Devi Thiagarajan, Robin Wilson, Raquel López Díez, Paul F. Gugger, Kaamashri Mangar, Navneet Narula, Stuart D. Katz, Boyan Zhou, Huilin Li, Aleksandr B. Stotland, Roberta A. Gottlieb, Ann Marie Schmidt, Alexander Shekhtman, Ravichandran Ramasamy
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-25 (2023)
Abstract Inter-organelle contact and communication between mitochondria and sarco/endoplasmic reticulum (SR/ER) maintain cellular homeostasis and are profoundly disturbed during tissue ischemia. We tested the hypothesis that the formin Diaphanous-1 (
Externí odkaz:
https://doaj.org/article/afb308148fa9402ea6f6e0d25ae3c38d
Autor:
Keshav Gopal, Qutuba G. Karwi, Seyed Amirhossein Tabatabaei Dakhili, Cory S. Wagg, Liyan Zhang, Qiuyu Sun, Christina T. Saed, Sai Panidarapu, Riccardo Perfetti, Ravichandran Ramasamy, John R. Ussher, Gary D. Lopaschuk
Publikováno v:
Cardiovascular Diabetology, Vol 22, Iss 1, Pp 1-12 (2023)
Abstract Background Cardiovascular diseases, including diabetic cardiomyopathy, are major causes of death in people with type 2 diabetes. Aldose reductase activity is enhanced in hyperglycemic conditions, leading to altered cardiac energy metabolism
Externí odkaz:
https://doaj.org/article/51239f61fe9f4aaa82e566b6c24008f4
Autor:
Laura Senatus, Lander Egaña-Gorroño, Raquel López-Díez, Sonia Bergaya, Juan Francisco Aranda, Jaume Amengual, Lakshmi Arivazhagan, Michaele B. Manigrasso, Gautham Yepuri, Ramesh Nimma, Kaamashri N. Mangar, Rollanda Bernadin, Boyan Zhou, Paul F. Gugger, Huilin Li, Richard A. Friedman, Neil D. Theise, Alexander Shekhtman, Edward A. Fisher, Ravichandran Ramasamy, Ann Marie Schmidt
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-20 (2023)
Male and female mice deficient in DIAPH1 are protected from the development of experimental atherosclerosis and display reduced cholesterol levels; these changes are linked to the regulation of SREBP1 subcellular localization.
Externí odkaz:
https://doaj.org/article/3b884c6d0ad746b0ae3401514cb0c693
Autor:
Nicholas Sciolino, Sergey Reverdatto, Aaron Premo, Leonard Breindel, Jianchao Yu, Gregory Theophall, David S. Burz, Anna Liu, Todd Sulchek, Ann Marie Schmidt, Ravichandran Ramasamy, Alexander Shekhtman
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-17 (2022)
Abstract Analytical tools to study cell physiology are critical for optimizing drug-host interactions. Real time pulse chase NMR spectroscopy, RTPC-NMR, was introduced to monitor the kinetics of metabolite production in HEK 293T cells treated with CO
Externí odkaz:
https://doaj.org/article/596fe7d7b2be492f8d0a909edb501da5
Autor:
Jide Oluwadare, Ainara G. Cabodevilla, Ni-Huiping Son, Yunying Hu, Adam E. Mullick, Michael Verano, Jose O. Alemán, Ravichandran Ramasamy, Ira J. Goldberg
Publikováno v:
Journal of Lipid Research, Vol 63, Iss 11, Pp 100274- (2022)
Lipid accumulation in nonadipose tissues can cause lipotoxicity, leading to cell death and severe organ dysfunction. Adipose triglyceride lipase (ATGL) deficiency causes human neutral lipid storage disease and leads to cardiomyopathy; ATGL deficiency
Externí odkaz:
https://doaj.org/article/f665ac1d40554a758d5215f1f0e19a98
Autor:
Lakshmi Arivazhagan, Raquel López-Díez, Alexander Shekhtman, Ravichandran Ramasamy, Ann Marie Schmidt
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
Obesity and non-alcoholic fatty liver disease (NAFLD) are on the rise world-wide; despite fervent advocacy for healthier diets and enhanced physical activity, these disorders persist unabated and, long-term, are major causes of morbidity and mortalit
Externí odkaz:
https://doaj.org/article/6f532574044947eba9d0def032933819
Autor:
Ravichandran, Ramasamy, Dixit, Preeti
Publikováno v:
Journal of Vocational Education Studies; May2024, Vol. 7 Issue 1, p81-100, 20p
Autor:
Erkan Tuncay, Ivan Gando, Jian-Yi Huo, Gautham Yepuri, Natalie Sampler, Belma Turan, Hua-Qian Yang, Ravichandran Ramasamy, William A. Coetzee
Publikováno v:
American Journal of Physiology-Cell Physiology. 324:C1017-C1027
Sirtuins are NAD+-dependent deacetylases with beneficial roles in conditions relevant to human health, including metabolic disease, type II diabetes, obesity, cancer, aging, neurodegenerative diseases, and cardiac ischemia. Since ATP-sensitive K+ (KA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3b8f5536727143b817a280c163e1f31
https://doi.org/10.1152/ajpcell.00459.2022
https://doi.org/10.1152/ajpcell.00459.2022
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2021)
Diabetes is a leading cause of cardiovascular morbidity and mortality. Despite numerous treatments for cardiovascular disease (CVD), for patients with diabetes, these therapies provide less benefit for protection from CVD. These considerations spur t
Externí odkaz:
https://doaj.org/article/eb03ddb9d7bb4655bc6e39c4fbc58bb1
Autor:
Lander Egaña-Gorroño, Raquel López-Díez, Gautham Yepuri, Lisa S. Ramirez, Sergey Reverdatto, Paul F. Gugger, Alexander Shekhtman, Ravichandran Ramasamy, Ann Marie Schmidt
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
Obesity and diabetes are leading causes of cardiovascular morbidity and mortality. Although extensive strides have been made in the treatments for non-diabetic atherosclerosis and its complications, for patients with diabetes, these therapies provide
Externí odkaz:
https://doaj.org/article/57b885d982324f2dbf9cd251e3c54370