Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ravian L van Ineveld"'
Autor:
Bernadette Jeremiasse, Ravian L van Ineveld, Veerle Bok, Michiel Kleinnijenhuis, Sam de Blank, Maria Alieva, Hannah R Johnson, Esmée J van Vliet, Amber L Zeeman, Lianne M Wellens, Gerard Llibre-Palomar, Mario Barrera Román, Alessia Di Maggio, Johanna F Dekkers, Sabrina Oliveira, Alexander L Vahrmeijer, Jan J Molenaar, Marc HWA Wijnen, Alida FW van der Steeg, Ellen J Wehrens, Anne C Rios
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 7, Pp 1495-1514 (2024)
Abstract Achieving complete tumor resection is challenging and can be improved by real-time fluorescence-guided surgery with molecular-targeted probes. However, pre-clinical identification and validation of probes presents a lengthy process that is t
Externí odkaz:
https://doaj.org/article/59beb6ac34b24791970db0bb11a508eb
Autor:
Camilla Calandrini, Frans Schutgens, Rurika Oka, Thanasis Margaritis, Tito Candelli, Luka Mathijsen, Carola Ammerlaan, Ravian L. van Ineveld, Sepide Derakhshan, Sanne de Haan, Emmy Dolman, Philip Lijnzaad, Lars Custers, Harry Begthel, Hindrik H. D. Kerstens, Lindy L. Visser, Maarten Rookmaaker, Marianne Verhaar, Godelieve A. M. Tytgat, Patrick Kemmeren, Ronald R. de Krijger, Reem Al-Saadi, Kathy Pritchard-Jones, Marcel Kool, Anne C. Rios, Marry M. van den Heuvel-Eibrink, Jan J. Molenaar, Ruben van Boxtel, Frank C. P. Holstege, Hans Clevers, Jarno Drost
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Pre-clinical cell culture models capturing the heterogeneity of childhood kidney tumours are limited. Here, the authors establish and characterise an organoid biobank of tumour and matched normal organoid cultures from over 50 children with different
Externí odkaz:
https://doaj.org/article/06e35408aaed4de9ae4266eeecb8d988
Autor:
Ravian L. van Ineveld, Raphaël Collot, Mario Barrera Román, Anna Pagliaro, Nils Bessler, Hendrikus C. R. Ariese, Michiel Kleinnijenhuis, Marcel Kool, Maria Alieva, Susana M. Chuva de Sousa Lopes, Ellen J. Wehrens, Anne C. Rios
Publikováno v:
Nature Protocols, 17(12), 3028-+. NATURE PORTFOLIO
Revealing the 3D composition of intact tissue specimens is essential for understanding cell and organ biology in health and disease. State-of-the-art 3D microscopy techniques aim to capture tissue volumes on an ever-increasing scale, while also retai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2956b1da246f4d51256a9fd94952e44
https://hdl.handle.net/1887/3563155
https://hdl.handle.net/1887/3563155
Autor:
Maria Alieva, Frank L. Bos, Anne C. Rios, Ellen J. Wehrens, Johanna F. Dekkers, Michiel Kleinnijenhuis, Hannah Johnson, Jarno Drost, Clara Martínez Mir, Raimond Heukers, Mario Barrera Roman, Sam de Blank, Esmée J. van Vliet, Ravian L. van Ineveld, Susana M. Chuva de Sousa Lopes
Publikováno v:
Nature Biotechnology
Nature Biotechnology, 39(10), 1239-1245. NATURE RESEARCH
Nature Biotechnology, 39(10), 1239-1245. NATURE RESEARCH
Despite advances in three-dimensional (3D) imaging, it remains challenging to profile all the cells within a large 3D tissue, including the morphology and organization of the many cell types present. Here, we introduce eight-color, multispectral, lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3bda6aec3ffafefa2656c82b7b58eca
https://doi.org/10.1038/s41587-021-00926-3
https://doi.org/10.1038/s41587-021-00926-3
Autor:
Johanna F. Dekkers, Maria Alieva, Astrid Cleven, Farid Keramati, Amber K. L. Wezenaar, Esmée J. van Vliet, Jens Puschhof, Peter Brazda, Inez Johanna, Angelo D. Meringa, Heggert G. Rebel, Maj-Britt Buchholz, Mario Barrera Román, Amber L. Zeeman, Sam de Blank, Domenico Fasci, Maarten H. Geurts, Annelisa M. Cornel, Else Driehuis, Rosemary Millen, Trudy Straetemans, Mara J. T. Nicolasen, Tineke Aarts-Riemens, Hendrikus C. R. Ariese, Hannah R. Johnson, Ravian L. van Ineveld, Froso Karaiskaki, Oded Kopper, Yotam E. Bar-Ephraim, Kai Kretzschmar, Alexander M. M. Eggermont, Stefan Nierkens, Ellen J. Wehrens, Henk G. Stunnenberg, Hans Clevers, Jürgen Kuball, Zsolt Sebestyen, Anne C. Rios
Publikováno v:
Nature Biotechnology. Nature Publishing Group
Extending the success of cellular immunotherapies against blood cancers to the realm of solid tumors will require improved in vitro models that reveal therapeutic modes of action at the molecular level. Here we describe a system, called BEHAV3D, deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f13e816394f157842a7bd4b7c168dfc
https://hdl.handle.net/20.500.11755/61e7d6c0-d595-417b-8a49-c504fbe82e8e
https://hdl.handle.net/20.500.11755/61e7d6c0-d595-417b-8a49-c504fbe82e8e
Publikováno v:
EMBO J
Our understanding of the cellular composition and architecture of cancer has primarily advanced using 2D models and thin slice samples. This has granted spatial information on fundamental cancer biology and treatment response. However, tissues contai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5082bf0acdf9b1cae4b3317490e2b598
https://doi.org/10.15252/embj.2021109675
https://doi.org/10.15252/embj.2021109675
Autor:
Ravian L, van Ineveld, Raphaël, Collot, Mario Barrera, Román, Anna, Pagliaro, Nils, Bessler, Hendrikus C R, Ariese, Michiel, Kleinnijenhuis, Marcel, Kool, Maria, Alieva, Susana M, Chuva de Sousa Lopes, Ellen J, Wehrens, Anne C, Rios
Publikováno v:
Nature protocols. 17(12)
Revealing the 3D composition of intact tissue specimens is essential for understanding cell and organ biology in health and disease. State-of-the-art 3D microscopy techniques aim to capture tissue volumes on an ever-increasing scale, while also retai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::478a1778fb74078b814c2214d271158f
https://pubmed.ncbi.nlm.nih.gov/36180532
https://pubmed.ncbi.nlm.nih.gov/36180532
Autor:
Ravian L. van Ineveld, Hendrikus C R Ariese, Ellen J. Wehrens, Anne C. Rios, Johanna F. Dekkers
Publikováno v:
Journal of visualized experiments : JoVE. (160)
Organoid technology, in vitro 3D culturing of miniature tissue, has opened a new experimental window for cellular processes that govern organ development and function as well as disease. Fluorescence microscopy has played a major role in characterizi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b08876f4fefc04b0f067c93f83741341
https://pubmed.ncbi.nlm.nih.gov/32568249
https://pubmed.ncbi.nlm.nih.gov/32568249
Autor:
Ravian L, van Ineveld, Michiel, Kleinnijenhuis, Maria, Alieva, Sam, de Blank, Mario, Barrera Roman, Esmée J, van Vliet, Clara, Martínez Mir, Hannah R, Johnson, Frank L, Bos, Raimond, Heukers, Susana M, Chuva de Sousa Lopes, Jarno, Drost, Johanna F, Dekkers, Ellen J, Wehrens, Anne C, Rios
Publikováno v:
Nature biotechnology. 39(10)
Despite advances in three-dimensional (3D) imaging, it remains challenging to profile all the cells within a large 3D tissue, including the morphology and organization of the many cell types present. Here, we introduce eight-color, multispectral, lar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e361d7d33bf4d921439a4a12533196f5
https://pubmed.ncbi.nlm.nih.gov/36045261
https://pubmed.ncbi.nlm.nih.gov/36045261
Autor:
Livio Trusolino, Francesco Sassi, Sander Mertens, Benjamin Cappe, Ingrid Verlaan-Klink, Ravian L. van Ineveld, Bas Ponsioen, Sylvia F. Boj, Simone Kersten, Julian R. Buissant des Amorie, Dimitrios Laskaris, Rob G. J. Vries, Franck B. Riquet, Andrea Bertotti, Jasmin B. Post, François Sipieter, Johannes L. Bos, Peter Vandenabeele, Hugo J. Snippert, Holger Rehmann
Publikováno v:
Nature cell biology
Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2021, 23 (4), pp.377-390. ⟨10.1038/s41556-021-00654-5⟩
Nature Cell Biology
Nature Cell Biology, Nature Publishing Group, 2021, 23 (4), pp.377-390. ⟨10.1038/s41556-021-00654-5⟩
Direct targeting of the downstream mitogen-activated protein kinase (MAPK) pathway to suppress extracellular-regulated kinase (ERK) activation in KRAS and BRAF mutant colorectal cancer (CRC) has proven clinically unsuccessful, but promising results h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d4b2749f92571a2f4402c00c4468380
https://pubmed.ncbi.nlm.nih.gov/33795873
https://pubmed.ncbi.nlm.nih.gov/33795873