Zobrazeno 1 - 10
of 236
pro vyhledávání: '"Ravi Varadhan"'
Autor:
Grant Schumock, Karen Bandeen-Roche, Chee W Chia, Rita R Kalyani, Luigi Ferrucci, Ravi Varadhan
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0302381 (2024)
As people age, their ability to maintain homeostasis in response to stressors diminishes. Physical frailty, a syndrome characterized by loss of resilience to stressors, is thought to emerge due to dysregulation of and breakdowns in communication amon
Externí odkaz:
https://doaj.org/article/9cadfc18de814abbad9093aa3fe00ca1
Autor:
Clifton P. Thornton, Karen Bandeen-Roche, Madeline Dolinar, Laken C. Roberts Lavigne, Dina George Lansey, Rick Jones, Jeremy Walston, Ravi Varadhan, Melissa Hladek, Philip Imus
Publikováno v:
BMC Geriatrics, Vol 23, Iss 1, Pp 1-7 (2023)
Abstract Background Older adults represent a large oncologic demographic and are under-represented within oncology research despite constituting nearly two-thirds of the oncologic population in the United States. Because many social factors influence
Externí odkaz:
https://doaj.org/article/7c2cca37c99145b0b4ad8eb72a43f93e
Autor:
Courtney M. Johnson, Sai M. Talluru, Bianka Bubic, Michelle Colbert, Priyanka Kumar, Hua-ling Tsai, Ravi Varadhan, Sima Rozati
Publikováno v:
JID Innovations, Vol 3, Iss 6, Pp 100219- (2023)
Mycosis fungoides/Sézary syndrome (MF/SS) produces a low-grade chronic inflammatory state that may be associated with an increased risk of cardiovascular (CV) events, as seen in other chronic, systemic dermatologic diseases. To assess this associati
Externí odkaz:
https://doaj.org/article/1fbd89b91f3742f7b194caf0057a1b8a
Autor:
Tania Jain, Hua-Ling Tsai, Hany Elmariah, Pankit Vachhani, Theodoros Karantanos, Sarah A Wall, Lukasz P. Gondek, Asad Bashey, Alla Keyzner, Roni Tamari, Michael R. Grunwald, Sameem Abedin, Kalyan VG Nadiminti, Madiha Iqbal, Aaron T Gerds, Auro Viswabandya, Shannon R McCurdy, Monzr M. Al Malki, Ravi Varadhan, Haris Ali, Vikas Gupta, Richard J. Jones, Salman Otoukesh
Publikováno v:
Haematologica, Vol 108, Iss 12 (2023)
Haploidentical donors offer a potentially readily available donor, especially for non-White patients, for hematopoietic cell transplantation (HCT). In this North American collaboration, we retrospectively analyzed outcomes of first HCT using haploide
Externí odkaz:
https://doaj.org/article/570bb8349f634e309f784c10d640f28c
Publikováno v:
Journal of Dermatological Treatment, Vol 35, Iss 1 (2024)
Externí odkaz:
https://doaj.org/article/8520089ab9ad4f519b04b84f131ad2d2
Autor:
Theodoros Karantanos, Patric Teodorescu, Marios Arvanitis, Brandy Perkins, Tania Jain, Amy E. DeZern, W. Brian Dalton, Ilias Christodoulou, Bogdan C. Paun, Ravi Varadhan, Christopher Esteb, Trivikram Rajkhowa, Challice Bonifant, Lukasz P. Gondek, Mark J. Levis, Srinivasan Yegnasubramanian, Gabriel Ghiaur, Richard J. Jones
Publikováno v:
Haematologica, Vol 108, Iss 7 (2022)
Better understanding of the biology of resistance to DNA methyltransferase (DNMT) inhibitors is required to identify therapies that can improve their efficacy for patients with high-risk myelodysplastic syndrome (MDS). CCRL2 is an atypical chemokine
Externí odkaz:
https://doaj.org/article/92f4a560efe840b0991230f4b175b9cf
SQUAREM: An R Package for Off-the-Shelf Acceleration of EM, MM and Other EM-Like Monotone Algorithms
Autor:
Yu Du, Ravi Varadhan
Publikováno v:
Journal of Statistical Software, Vol 92, Iss 1, Pp 1-41 (2020)
We discuss the R package SQUAREM for accelerating iterative algorithms which exhibit slow, monotone convergence. These include the well-known expectation-maximization algorithm, majorize-minimize (MM), and other EM-like algorithms such as expectation
Externí odkaz:
https://doaj.org/article/0f97ef1d7dd4405abc690866a5d51de5
Autor:
Alexander J. Ambinder, Kelly Norsworthy, Daniela Hernandez, Laura Palau, Bogdan Paun, Amy Duffield, Rosh Chandraratna, Martin Sanders, Ravi Varadhan, Richard J. Jones, B. Douglas Smith, Gabriel Ghiaur
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Subsets of non-acute promyelocytic leukemia (APL) acute myelogenous leukemia (AML) exhibit aberrant retinoid signaling and demonstrate sensitivity to retinoids in vitro. We present the results of a phase 1 dose-escalation study that evaluated the saf
Externí odkaz:
https://doaj.org/article/3231cdf791a348b9a078c4d69e0c7121
Publikováno v:
Journal of Statistical Software, Vol 85, Iss 1, Pp 1-31 (2018)
In patient-centered outcomes research, it is essential to assess the heterogeneity of treatment effects (HTE) when making health care decisions for an individual patient or a group of patients. Nevertheless, it remains challenging to evaluate HTE bas
Externí odkaz:
https://doaj.org/article/086635ed95a24e18863f2ac97a0fda64
Autor:
Abdulla A. Damluji, Jin Huang, Karen Bandeen‐Roche, Daniel E. Forman, Gary Gerstenblith, Mauro Moscucci, Jon R. Resar, Ravi Varadhan, Jeremy D. Walston, Jodi B. Segal
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 8, Iss 17 (2019)
Background Frailty is a predictor of adverse outcomes after acute myocardial infarction (AMI). Methods and Results We estimated the prevalence of frailty among adults age ≥75 years admitted with AMI and examined the relationship between frailty, in
Externí odkaz:
https://doaj.org/article/ac1b19515de84e649442d3992c718c04