Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ravi U, Sheth"'
Autor:
Christian Munck, Ravi U. Sheth, Edward Cuaresma, Jessica Weidler, Stephania L. Stump, Philip Zachariah, David H. Chong, Anne-Catrin Uhlemann, Julian A. Abrams, Harris H. Wang, Daniel E. Freedberg
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-10 (2020)
Abstract Background The need for early antibiotics in the intensive care unit (ICU) is often balanced against the goal of antibiotic stewardship. Long-course antibiotics increase the burden of antimicrobial resistance within colonizing gut bacteria,
Externí odkaz:
https://doaj.org/article/1f941ee7d7b1477dacd9c6d9879f5091
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Horizontal gene transfer (HGT) in complex bacterial communities has been mostly studied using metagenomic analyses. Here, the authors develop an E. coli CRISPR-Cas spacer acquisition platform that allows real-time recording of HGT events at nucleotid
Externí odkaz:
https://doaj.org/article/f36c8c6e1cf94ca1940242b3347cd40a
Autor:
Kristina N‐M Daeffler, Jeffrey D Galley, Ravi U Sheth, Laura C Ortiz‐Velez, Christopher O Bibb, Noah F Shroyer, Robert A Britton, Jeffrey J Tabor
Publikováno v:
Molecular Systems Biology, Vol 13, Iss 4, Pp 1-13 (2017)
Abstract There is a groundswell of interest in using genetically engineered sensor bacteria to study gut microbiota pathways, and diagnose or treat associated diseases. Here, we computationally identify the first biological thiosulfate sensor and an
Externí odkaz:
https://doaj.org/article/7129d61cd9c54e3b96037757c869c69f
Autor:
Yiming Huang, Ravi U. Sheth, Shijie Zhao, Lucas A. Cohen, Kendall Dabaghi, Thomas Moody, Yiwei Sun, Deirdre Ricaurte, Miles Richardson, Florencia Velez-Cortes, Tomasz Blazejewski, Andrew Kaufman, Carlotta Ronda, Harris H. Wang
Publikováno v:
Nature Biotechnology.
Pure bacterial cultures remain essential for detailed experimental and mechanistic studies in microbiome research, and traditional methods to isolate individual bacteria from complex microbial ecosystems are labor-intensive, difficult-to-scale and la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39d4e157678b3fc496b40c8752fdcf36
https://doi.org/10.1038/s41587-023-01674-2
https://doi.org/10.1038/s41587-023-01674-2
Autor:
Guillaume Urtecho, Thomas Moody, Yiming Huang, Ravi U. Sheth, Miles Richardson, Opeyemi Lekan, Florencia Velez-Cortes, Deirdre Ricaurte, Harris H. Wang
Gastrointestinal colonization by commensal bacteria is a reproducible yet complex process. Mapping the spatiotemporal and genetic factors driving microbial colonization of the gut is key to understanding the gut microbiome and improving clinical inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a460f70265a5b3e0d2845785d869e2e
https://doi.org/10.1101/2022.10.21.513299
https://doi.org/10.1101/2022.10.21.513299
Publikováno v:
Nature Microbiology. 5:768-775
The gut microbiota is now widely recognized as a dynamic ecosystem that plays an important role in health and disease. Although current sequencing technologies make it possible to explore how relative abundances of host-associated bacteria change ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07b619461bd341a290bff377eac1bac0
https://doi.org/10.1038/s41564-020-0685-1
https://doi.org/10.1038/s41564-020-0685-1
Autor:
Karl P. Gerhardt, Ravi U. Sheth, Felix Ekness, Brian P. Landry, Kathryn R. Brink, Kristina N.-M. Daeffler, Nikola Dyulgyarov, Katri Sofjan, Sebastian R. Schmidl, Jeffrey J. Tabor
Publikováno v:
Nature Chemical Biology. 15:690-698
Two-component systems (TCSs) are the largest family of multi-step signal transduction pathways and valuable sensors for synthetic biology. However, most TCSs remain uncharacterized or difficult to harness for applications. Major challenges are that m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c59772d2104161242e2bf72ff65ee6
https://doi.org/10.1038/s41589-019-0286-6
https://doi.org/10.1038/s41589-019-0286-6
Autor:
Ravi U. Sheth, Julian A. Abrams, Jessica Weidler, Daniel E. Freedberg, Philip Zachariah, Stephania Stump, Edward Cuaresma, Christian Munck, Anne-Catrin Uhlemann, David H. Chong, Harris H. Wang
Publikováno v:
Critical Care, Vol 24, Iss 1, Pp 1-10 (2020)
Critical Care
Critical Care
Background The need for early antibiotics in the intensive care unit (ICU) is often balanced against the goal of antibiotic stewardship. Long-course antibiotics increase the burden of antimicrobial resistance within colonizing gut bacteria, but the d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff049143ec4479fef984cc47a90f147b
https://doi.org/10.21203/rs.2.23155/v2
https://doi.org/10.21203/rs.2.23155/v2
Publikováno v:
Nature chemical biology. 17(3)
DNA has been the predominant information storage medium for biology and holds great promise as a next-generation high-density data medium in the digital era. Currently, the vast majority of DNA-based data storage approaches rely on in vitro DNA synth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::600ff031ffa0bafce80d096e5b1ba997
https://pubmed.ncbi.nlm.nih.gov/33500580
https://pubmed.ncbi.nlm.nih.gov/33500580
Publikováno v:
Science
A CRISPR device to record time The CRISPR adaptation system has been used to record the sequence and ordering of exogenous oligonucleotides that are electroporated into cell populations. Sheth et al. engineered a system bypassing the use of exogenous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad049d02eed16ce797865330c7fd1813
https://doi.org/10.1126/science.aao0958
https://doi.org/10.1126/science.aao0958