Zobrazeno 1 - 10 of 28 pro vyhledávání: '"Ravi Sundar Jose Geetha A"'
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Akademický článek
Dynamic control of gene expression by ISGF3 and IRF1 during IFNβ and IFNγ signaling.
Autor: Ravi Sundar Jose Geetha A; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, 1030, Austria.; University of Vienna, Center for Molecular Biology, Department of Microbiology, Immunobiology and Genetics, Vienna, 1030, Austria., Fischer K; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, 1030, Austria.; University of Vienna, Center for Molecular Biology, Department of Microbiology, Immunobiology and Genetics, Vienna, 1030, Austria., Babadei O; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, 1030, Austria.; University of Vienna, Center for Molecular Biology, Department of Microbiology, Immunobiology and Genetics, Vienna, 1030, Austria., Smesnik G; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, 1030, Austria.; University of Vienna, Center for Molecular Biology, Department of Microbiology, Immunobiology and Genetics, Vienna, 1030, Austria., Vogt A; Evotec, Hamburg, Germany., Platanitis E; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, 1030, Austria.; University of Vienna, Center for Molecular Biology, Department of Microbiology, Immunobiology and Genetics, Vienna, 1030, Austria., Müller M; Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, 1210, Austria., Farlik M; Department of Dermatology, Medical University of Vienna, Vienna, 1090, Austria., Decker T; Max Perutz Labs, Vienna Biocenter Campus (VBC), Vienna, 1030, Austria. thomas.decker@univie.ac.at.; University of Vienna, Center for Molecular Biology, Department of Microbiology, Immunobiology and Genetics, Vienna, 1030, Austria. thomas.decker@univie.ac.at.
Publikováno v: The EMBO journal [EMBO J] 2024 Jun; Vol. 43 (11), pp. 2233-2263. Date of Electronic Publication: 2024 Apr 24.
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3
Akademický článek
Interferons reshape the 3D conformation and accessibility of macrophage chromatin
Autor: Ekaterini Platanitis, Stephan Gruener, Aarathy Ravi Sundar Jose Geetha, Laura Boccuni, Alexander Vogt, Maria Novatchkova, Andreas Sommer, Iros Barozzi, Mathias Müller, Thomas Decker
Publikováno v: iScience, Vol 25, Iss 3, Pp 103840- (2022)
Summary: Engagement of macrophages in innate immune responses is directed by type I and type II interferons (IFN-I and IFN-γ, respectively). IFN triggers drastic changes in cellular transcriptomes, executed by JAK-STAT signal transduction and the tr
Externí odkaz: https://doaj.org/article/1a6f6eee862e4cd9af2120c430906861
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4
Akademický článek
JAK-STAT signaling maintains homeostasis in T cells and macrophages.
Autor: Fortelny N; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Center for Tumor Biology and Immunology, Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Salzburg, Austria., Farlik M; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria. matthias.farlik@meduniwien.ac.at.; Department of Dermatology, Medical University of Vienna, Vienna, Austria. matthias.farlik@meduniwien.ac.at., Fife V; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Gorki AD; Research Division of Infection Biology, Department of Medicine I, Medical University of Vienna, Vienna, Austria., Lassnig C; Animal Breeding and Genetics and VetBiomodels, Department of Biological Sciences and Pathobiology, University of Veterinary Medicine, Vienna, Austria., Maurer B; Pharmacology and Toxicology, Department of Biological Sciences and Pathobiology, University of Veterinary Medicine, Vienna, Austria., Meissl K; Animal Breeding and Genetics and VetBiomodels, Department of Biological Sciences and Pathobiology, University of Veterinary Medicine, Vienna, Austria., Dolezal M; Platform for Bioinformatics and Biostatistics, Department of Biological Sciences and Pathobiology, University of Veterinary Medicine, Vienna, Austria., Boccuni L; Max Perutz Labs, University of Vienna, Vienna, Austria., Ravi Sundar Jose Geetha A; Max Perutz Labs, University of Vienna, Vienna, Austria., Akagha MJ; Animal Breeding and Genetics and VetBiomodels, Department of Biological Sciences and Pathobiology, University of Veterinary Medicine, Vienna, Austria., Karjalainen A; Animal Breeding and Genetics and VetBiomodels, Department of Biological Sciences and Pathobiology, University of Veterinary Medicine, Vienna, Austria., Shoebridge S; Animal Breeding and Genetics and VetBiomodels, Department of Biological Sciences and Pathobiology, University of Veterinary Medicine, Vienna, Austria., Farhat A; Research Division of Infection Biology, Department of Medicine I, Medical University of Vienna, Vienna, Austria., Mann U; Department of Dermatology, Medical University of Vienna, Vienna, Austria., Jain R; Department of Dermatology, Medical University of Vienna, Vienna, Austria., Tikoo S; Department of Dermatology, Medical University of Vienna, Vienna, Austria., Zila N; Department of Dermatology, Medical University of Vienna, Vienna, Austria., Esser-Skala W; Center for Tumor Biology and Immunology, Department of Biosciences and Medical Biology, Paris-Lodron University Salzburg, Salzburg, Austria., Krausgruber T; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria.; Institute of Artificial Intelligence, Center for Medical Data Science, Medical University of Vienna, Vienna, Austria., Sitnik K; Animal Breeding and Genetics and VetBiomodels, Department of Biological Sciences and Pathobiology, University of Veterinary Medicine, Vienna, Austria., Penz T; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Hladik A; Research Division of Infection Biology, Department of Medicine I, Medical University of Vienna, Vienna, Austria., Suske T; Animal Breeding and Genetics and VetBiomodels, Department of Biological Sciences and Pathobiology, University of Veterinary Medicine, Vienna, Austria., Zahalka S; Research Division of Infection Biology, Department of Medicine I, Medical University of Vienna, Vienna, Austria., Senekowitsch M; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Barreca D; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Halbritter F; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria., Macho-Maschler S; Animal Breeding and Genetics and VetBiomodels, Department of Biological Sciences and Pathobiology, University of Veterinary Medicine, Vienna, Austria., Weninger W; Department of Dermatology, Medical University of Vienna, Vienna, Austria., Neubauer HA; Animal Breeding and Genetics and VetBiomodels, Department of Biological Sciences and Pathobiology, University of Veterinary Medicine, Vienna, Austria., Moriggl R; Animal Breeding and Genetics and VetBiomodels, Department of Biological Sciences and Pathobiology, University of Veterinary Medicine, Vienna, Austria., Knapp S; Research Division of Infection Biology, Department of Medicine I, Medical University of Vienna, Vienna, Austria., Sexl V; Pharmacology and Toxicology, Department of Biological Sciences and Pathobiology, University of Veterinary Medicine, Vienna, Austria.; University of Innsbruck, Innsbruck, Austria., Strobl B; Animal Breeding and Genetics and VetBiomodels, Department of Biological Sciences and Pathobiology, University of Veterinary Medicine, Vienna, Austria., Decker T; Max Perutz Labs, University of Vienna, Vienna, Austria., Müller M; Animal Breeding and Genetics and VetBiomodels, Department of Biological Sciences and Pathobiology, University of Veterinary Medicine, Vienna, Austria., Bock C; CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, Vienna, Austria. cbock@cemm.oeaw.ac.at.; Institute of Artificial Intelligence, Center for Medical Data Science, Medical University of Vienna, Vienna, Austria. cbock@cemm.oeaw.ac.at.
Publikováno v: Nature immunology [Nat Immunol] 2024 May; Vol. 25 (5), pp. 847-859. Date of Electronic Publication: 2024 Apr 24.
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5
Interferons reshape the 3D conformation and accessibility of macrophage chromatin
Autor: Thomas Decker, Andreas Sommer, Stephan Grüner, Ekaterini Platanitis, Alexander Vogt, Laura Boccuni, Aarathy Ravi Sundar Jose Geetha, Maria Novachkova, Mathias Müller
Publikováno v: iScience, Vol 25, Iss 3, Pp 103840-(2022)
Summary: Engagement of macrophages in innate immune responses is directed by type I and type II interferons (IFN-I and IFN-γ, respectively). IFN triggers drastic changes in cellular transcriptomes, executed by JAK-STAT signal transduction and the tr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08a646e5b061ebe1e141fd2cd39b2a75
https://pubmed.ncbi.nlm.nih.gov/35243225
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6
Akademický článek
Exploring the Blood Biomarkers and Potential Therapeutic Agents for Human Acute Mountain Sickness Based on Transcriptomic Analysis, Inflammatory Infiltrates and Molecular Docking.
Autor: Yan, Jiayi1,2 (AUTHOR) yjy19951025@163.com, Zhang, Zhuo2 (AUTHOR) luckwin@yeah.net, Ge, Yunxuan2 (AUTHOR) 15088094928@163.com, Chen, Junru2,3 (AUTHOR), Gao, Yue1,2 (AUTHOR) gaoyue@bmi.ac.cn, Zhang, Boli1 (AUTHOR) gaoyue@bmi.ac.cn
Publikováno v: International Journal of Molecular Sciences. Oct2024, Vol. 25 Issue 20, p11311. 12p.
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7
Akademický článek
Threonine Phosphorylation and the Yin and Yang of STAT1: Phosphorylation-Dependent Spectrum of STAT1 Functionality in Inflammatory Contexts.
Autor: Elbrashy, Maha M.1,2 (AUTHOR) mahahosny36@ifrec.osaka-u.ac.jp, Metwally, Hozaifa1 (AUTHOR) hozaifa1@ifrec.osaka-u.ac.jp, Sakakibara, Shuhei1,3 (AUTHOR), Kishimoto, Tadamitsu1 (AUTHOR) hozaifa1@ifrec.osaka-u.ac.jp
Publikováno v: Cells (2073-4409). Sep2024, Vol. 13 Issue 18, p1531. 14p.
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9
Akademický článek
Merkel cell polyomavirus small tumor antigen contributes to immune evasion by interfering with type I interferon signaling.
Autor: Ohnezeit, Denise1 (AUTHOR), Huang, Jiabin1 (AUTHOR), Westerkamp, Ute1 (AUTHOR), Brinschwitz, Veronika1 (AUTHOR), Schmidt, Claudia1 (AUTHOR), Günther, Thomas2 (AUTHOR), Czech-Sioli, Manja1 (AUTHOR), Weißelberg, Samira1 (AUTHOR), Schlemeyer, Tabea1 (AUTHOR), Nakel, Jacqueline2 (AUTHOR), Mai, Julia3,4 (AUTHOR), Schreiner, Sabrina3,4 (AUTHOR), Schneider, Carola2 (AUTHOR), Friedel, Caroline C.5 (AUTHOR), Schwanke, Hella6 (AUTHOR), Brinkmann, Melanie M.6,7 (AUTHOR), Grundhoff, Adam2 (AUTHOR), Fischer, Nicole1 (AUTHOR) nfischer@uke.de
Publikováno v: PLoS Pathogens. 8/7/2024, Vol. 20 Issue 8, p1-35. 35p.
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10
Akademický článek
Non-Receptor Tyrosine Kinases: Their Structure and Mechanistic Role in Tumor Progression and Resistance.
Autor: Eshaq, Abdulaziz M.1,2 (AUTHOR) eshaq@gwu.edu, Flanagan, Thomas W.3 (AUTHOR) tflan1@lsuhsc.edu, Hassan, Sofie-Yasmin4 (AUTHOR) sofie00@gmx.de, Al Asheikh, Sara A.2 (AUTHOR) walamoudi@alfaisal.edu, Al-Amoudi, Waleed A.2 (AUTHOR) maryam.o.alamodi@gmail.com, Santourlidis, Simeon5 (AUTHOR) simeon.santourlidis@med.uni-duesseldorf.de, Hassan, Sarah-Lilly6 (AUTHOR) saha109@hhu.de, Alamodi, Maryam O.2 (AUTHOR) m.alamodi1998@gmail.com, Bendhack, Marcelo L.7 (AUTHOR) marcelo@uro-onco.net, Alamodi, Mohammed O.2 (AUTHOR), Haikel, Youssef8,9,10 (AUTHOR) youssef.haikel@unistra.fr, Megahed, Mossad11 (AUTHOR) mmegahed@ukaachen.de, Hassan, Mohamed8,9,12 (AUTHOR) dr.hassan@gmx.de
Publikováno v: Cancers. Aug2024, Vol. 16 Issue 15, p2754. 34p.
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