Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Ravi S. Muddashetty"'
Autor:
Naveen Kumar Chandappa Gowda, Bharti Nawalpuri, Sarayu Ramakrishna, Vishwaja Jhaveri, Ravi S. Muddashetty
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Epitranscriptome modifications are crucial in translation regulation and essential for maintaining cellular homeostasis. N6 methyladenosine (m6A) is one of the most abundant and well-conserved epitranscriptome modifications, which is known t
Externí odkaz:
https://doaj.org/article/aa420af04d3541478b77b4b184b3c696
Autor:
Michelle Ninochka D'Souza, Naveen Kumar Chandappa Gowda, Vishal Tiwari, Rosana Ottakandathil Babu, Praveen Anand, Sudhriti Ghosh Dastidar, Randhir Singh, Owen G. James, Bhuvaneish Selvaraj, Rakhi Pal, Arati Ramesh, Sumantra Chattarji, Siddharthan Chandran, Akash Gulyani, Dasaradhi Palakodeti, Ravi S. Muddashetty
Publikováno v:
iScience, Vol 9, Iss , Pp 399-411 (2018)
Summary: FMRP is an RNA-binding protein that is known to localize in the cytoplasm and in the nucleus. Here, we have identified an interaction of FMRP with a specific set of C/D box snoRNAs in the nucleus. C/D box snoRNAs guide 2’O methylations of
Externí odkaz:
https://doaj.org/article/cb878e62eeb44157894b15aa761e47cc
Publikováno v:
Frontiers in Molecular Biosciences, Vol 7 (2020)
Activity-dependent protein synthesis plays an important role during neuronal development by fine-tuning the formation and function of neuronal circuits. Recent studies have shown that miRNAs are integral to this regulation because of their ability to
Externí odkaz:
https://doaj.org/article/1f47279116ad4b24b668ed50741b5cfb
Publikováno v:
Stem Cell Research, Vol 39, Iss , Pp - (2019)
Mutations in FMR1 gene is the cause of Fragile X Syndrome (FXS) leading inherited cause of intellectual disability and autism spectrum disorders. FMR1 gene encodes Fragile X Mental Retardation Protein (FMRP) which is a RNA binding protein and play im
Externí odkaz:
https://doaj.org/article/cedfbffbc6234ed9a61146e8f4340c11
Autor:
Abhik Paul, Bharti Nawalpuri, Devanshi Shah, Shruthi Sateesh, Ravi S. Muddashetty, James P. Clement
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
SYNGAP1, a Synaptic Ras-GTPase activating protein, regulates synapse maturation during a critical developmental window. Heterozygous mutation in SYNGAP1 (SYNGAP1-/+) has been shown to cause Intellectual Disability (ID) in children. Recent studies hav
Externí odkaz:
https://doaj.org/article/75f35cb539954df3be246fbd968d50a1
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 12 (2019)
Dendritic growth and branching are highly regulated processes and are essential for establishing proper neuronal connectivity. There is a critical phase of early dendrite development when these are heavily regulated by external cues such as trophic f
Externí odkaz:
https://doaj.org/article/58f4516e2d75413fa3619f08da1ebd54
Autor:
Michelle Ninochka D’Souza, Sarayu Ramakrishna, Bindushree K. Radhakrishna, Vishwaja Jhaveri, Sreenath Ravindran, Lahari Yeramala, Deepak Nair, Dasaradhi Palakodeti, Ravi S. Muddashetty
Publikováno v:
Molecular Neurobiology. 59:7370-7392
The Fragile-X Mental Retardation Protein (FMRP) is an RNA binding protein that regulates translation of mRNAs essential for synaptic development and plasticity. FMRP interacts with a specific set of mRNAs, aids in their microtubule-dependent transpor
Autor:
Ravi S. Muddashetty, James P. Clement, Vijaya Verma, Ravi Manjithaya, M. J. Vijay Kumar, Thomas Behnisch, Sridhar Rajaram, Kavita Sharma
Publikováno v:
Experimental Brain Research. 240:289-309
Haploinsufficiency in SYNGAP1 is implicated in intellectual disability (ID) and autism spectrum disorder (ASD) and affects the maturation of dendritic spines. The abnormal spine development has been suggested to cause a disbalance of excitatory and i
Autor:
Pradip Paul, Sarayu Ramakrishna, Vivek Ghose, Gourav Dey, Ravi S Muddashetty, Meera Purushottam, Biju Viswanath, Sanjeev Jain, Reeteka Sud
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Ravi S. Muddashetty, Sudhriti Ghosh Dastidar, Aditi Bhattacharya, Sumantra Chattarji, Sumita Chakraborty, Shreya Das Sharma
Publikováno v:
EMBO Rep
Neuronal activity is responsible for large energy consumption within the brain. However, the cellular mechanisms draining ATP upon the arrival of a stimulus are yet to be explored systematically at the post-synapse. Here we provide evidence that a si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84b1e8384c6ea50719180f00f6cbacb5
https://europepmc.org/articles/PMC8811643/
https://europepmc.org/articles/PMC8811643/