Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ravi S. Harapanhalli"'
Publikováno v:
ract. 79:73-76
Autor:
Ravi S. Harapanhalli, Peter L. Jones, S. James Adelstein, Ashfaq Mahmood, Khalid Z. Matalka, Amin I. Kassis
Publikováno v:
ract. 79:77-82
Autor:
Roger W. Howell, Ravi S. Harapanhalli, Amin I. Kassis, McLaughlin Lw, Adelstein Sj, Dandamudi V. Rao
Publikováno v:
Journal of Medicinal Chemistry. 39:4804-4809
An iodinated analog of the DNA-minor-groove-binding agent Hoechst 33342 has been synthesized and evaluated for DNA binding and tumor targeting. The bis-benzimidazole ring system of the title compound was constructed from the piperazinyl terminus via
Autor:
Ravi S. Harapanhalli
Publikováno v:
Seminars in nuclear medicine. 40(5)
In March 2004, the Food and Drug Administration (FDA) published a report entitled Challenge and Opportunity on the Critical Path to New Medical Products in which it explained the critical path to medical product development and called for a nationwid
Autor:
Ravi S. Harapanhalli
Publikováno v:
ChemInform. 40
Autor:
Ravi S. Harapanhalli
Publikováno v:
Formulation and Analytical Development for Low-Dose Oral Drug Products
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9aca40c16340dbb311e28cc29509983
https://doi.org/10.1002/9780470386361.ch18
https://doi.org/10.1002/9780470386361.ch18
Autor:
Amin I. Kassis, S. James Adelstein, Ravi S. Harapanhalli, Bassam A. Dahman, Nan-hui Ho, Ketai Wang, Kai Chen
Publikováno v:
Bioconjugate chemistry. 13(2)
We have developed a new strategy that aims to concentrate therapeutic radionuclides within solid tumors. This approach, which we have named EMIT (enzyme-mediated insolubilization therapy), is a method for enzyme-dependent, site-specific, in vivo prec
Publikováno v:
International journal of radiation biology. 75(12)
The incubation of the DNA minor-groove binder [125I]iodoHoechst 33342 (125IH) with plasmid DNA leads to the production of one double-strand break (dsb) per decay, both in the presence and absence of dimethylsulfoxide (DMSO). In contrast, when 125I is
Publikováno v:
Journal of medicinal chemistry. 41(12)
The synthesis of halogenated rhodamine (Rh) derivatives was carried out by controlling the stoichiometry of the halogenating agents, bromine and iodine monochloride. In the no-carrier-added synthesis of radioiodinated rhodamine 123, direct labeling o
Autor:
S. James Adelstein, Khalid Z. Matalka, Ashfaq Mahmood, Amin I. Kassis, Peter L. Jones, Ravi S. Harapanhalli
Publikováno v:
Nuclear medicine and biology. 25(3)
Ethidium homodimer (EHD) was conjugated to B72.3 monoclonal antibody using a method whereby 85-90% of the conjugated EHD remains available for DNA intercalation. Antibody was thiopropionylated by reaction with N-succinimidyl 3-(2-pyridyldithio)propio