Výsledky vyhledávání - "Ravi S, Keshari"

Akademický článek

Early Antibiotic Exposure Alters Intestinal Development and Increases Susceptibility to Necrotizing Enterocolitis: A Mechanistic Study

Autor: Hala Chaaban, Maulin M. Patel, Kathryn Burge, Jeffrey V. Eckert, Cristina Lupu, Ravi S. Keshari, Robert Silasi, Girija Regmi, MaJoi Trammell, David Dyer, Steven J. McElroy, Florea Lupu

Publikováno v: Microorganisms, Vol 10, Iss 3, p 519 (2022)

Increasing evidence suggests that prolonged antibiotic therapy in preterm infants is associated with increased mortality and morbidities, such as necrotizing enterocolitis (NEC), a devastating gastrointestinal pathology characterized by intestinal in

Externí odkaz: https://doaj.org/article/3605f9087b644617a63fa315a632cb04

Zobrazit plný text záznamu

Akademický článek

C3 Opsonization of Anthrax Bacterium and Peptidoglycan Supports Recognition and Activation of Neutrophils

Autor: Narcis I. Popescu, Ravi S. Keshari, Jackie Cochran, K. Mark Coggeshall, Florea Lupu

Publikováno v: Microorganisms, Vol 8, Iss 7, p 1039 (2020)

Neutrophils are the most abundant innate cell population and a key immune player against invading pathogens. Neutrophils can kill both bacterium and spores of Bacillus anthracis, the causative anthrax pathogen. Unlike interactions with professional p

Externí odkaz: https://doaj.org/article/6a1f078d648c4010a2bb59108c755a14

Zobrazit plný text záznamu

Akademický článek

Role of ADTRP (Androgen‐Dependent Tissue Factor Pathway Inhibitor Regulating Protein) in Vascular Development and Function

Autor: Maulin M. Patel, Amanda R. Behar, Robert Silasi, Girija Regmi, Christopher L. Sansam, Ravi S. Keshari, Florea Lupu, Cristina Lupu

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 22 (2018)

Background The physiological function of ADTRP (androgen‐dependent tissue factor pathway inhibitor regulating protein) is unknown. We previously identified ADTRP as coregulating with and supporting the anticoagulant activity of tissue factor pathwa

Externí odkaz: https://doaj.org/article/d9c6d72becd448488f6b53dd5124b376

Zobrazit plný text záznamu

Complement C5 inhibition protects against hemolytic anemia and acute kidney injury in anthrax peptidoglycan-induced sepsis in baboons

Autor: Robert Silasi, Narcis I. Popescu, Alonso Ricardo, Girija Regmi, Cristina Lupu, K. Mark Coggeshall, Ravi S. Keshari, Florea Lupu, Joe H. Simmons

Publikováno v: Proc Natl Acad Sci U S A

Late-stage anthrax infections are characterized by dysregulated immune responses and hematogenous spread of Bacillus anthracis, leading to extreme bacteremia, sepsis, multiple organ failure, and, ultimately, death. Despite the bacterium being nonhemo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8501584aa74da4203b30a4f515050183
https://doi.org/10.1073/pnas.2104347118

Zobrazit plný text záznamu

Endothelial PAI-1 (Plasminogen Activator Inhibitor-1) Blocks the Intrinsic Pathway of Coagulation, Inducing the Clearance and Degradation of FXIa (Activated Factor XI)

Autor: David Gailani, Cristina Puy, Andras Gruber, Matthew W. Hagen, Anh T. P. Ngo, Owen J. T. McCarty, Monica T. Hinds, Jiaqing Pang, Florea Lupu, Ravi S. Keshari

Publikováno v: Arterioscler Thromb Vasc Biol

Objective— Activation of coagulation FXI (factor XI) by FXIIa (activated factor XII) is a prothrombotic process. The endothelium is known to play an antithrombotic role by limiting thrombin generation and platelet activation. It is unknown whether

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94fd65afe383f0d3606bf1cf17f25d3e
https://doi.org/10.1161/atvbaha.119.312619

Zobrazit plný text záznamu

Acceleration of Small Intestine Development and Remodeling of the Microbiome Following Hyaluronan 35 kDa Treatment in Neonatal Mice

Autor: Cristina Lupu, Robert Silasi, Girija Regmi, Ravi S. Keshari, Kathryn Burge, Misty Good, Florea Lupu, Majoi A. Trammell, Hala Chaaban, Steven J. McElroy, Jeffrey Eckert, David W. Dyer

Publikováno v: Nutrients
Nutrients, vol 13, iss 6
Nutrients, Vol 13, Iss 2030, p 2030 (2021)
Volume 13
Issue 6

The beneficial effects of human milk suppressing the development of intestinal pathologies such as necrotizing enterocolitis in preterm infants are widely known. Human milk (HM) is rich in a multitude of bioactive factors that play major roles in pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d58bf0a7c5c8345ebb2ce710e9f51030
http://europepmc.org/articles/PMC8231646

Zobrazit plný text záznamu

CD14 inhibition improves survival and attenuates thrombo-inflammation and cardiopulmonary dysfunction in a baboon model of Escherichia coli sepsis

Autor: Robert Silasi, Girija Regmi, Hala Chaaban, Narcis I. Popescu, Ravi S. Keshari, Florea Lupu, Cristina Lupu, John D. Lambris, Tom Eirik Mollnes

Publikováno v: J Thromb Haemost

Background During sepsis, gram‐negative bacteria induce robust inflammation primarily via lipopolysacharride (LPS) signaling through TLR4, a process that involves the glycosylphosphatidylinositol (GPI)‐anchored receptor CD14 transferring LPS to t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7daa448f01ba3f936b7472daa07c7eb
https://hdl.handle.net/10037/29102

Zobrazit plný text záznamu

C3 Opsonization of Anthrax Bacterium and Peptidoglycan Supports Recognition and Activation of Neutrophils

Autor: K. Mark Coggeshall, Ravi S. Keshari, Florea Lupu, Jackie Cochran, Narcis I. Popescu

Publikováno v: Microorganisms, Vol 8, Iss 1039, p 1039 (2020)
Microorganisms
Volume 8
Issue 7

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a74e6120658b0be6238ccb005c244945
https://www.mdpi.com/2076-2607/8/7/1039

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání