Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ravi Kumar Alluri"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
Reactive oxygen species (ROS) generated under oxidative stress (OS) cause oxidative damage to RNA. Recent studies have suggested a role for oxidized RNA in several human disorders. Under the conditions of oxidative stress, mRNAs released from polysom
Externí odkaz:
https://doaj.org/article/0a3954a969574db8bf987711498f3c24
Autor:
Alvin H. Schmaier, Dana E. Angelini, Ravi Kumar Alluri, John Barnard, Suman Kundu, Keith R. McCrae, Edward P. Feener, Samantha A. Whitney, Victor Chatterjee, Alok A. Khorana, Young Jun Shim, Dewen You, Shadi Swaidani, Alona Merkulova
Publikováno v:
Blood Advances
Key Points Cleaved HK is observed in many patients with cancer, suggesting activation of the contact system.EVs from cancer cell lines or patients with cancer express polyphosphate, bind and activate FXII, and are prothrombotic.
Visual Abstract<
Visual Abstract<
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20370bd70436fc1df9423e0e59c0c7fe
http://europepmc.org/articles/PMC8759128
http://europepmc.org/articles/PMC8759128
Autor:
Xuan Yuan, Robert A. Brodsky, Michelle Petri, Michael B. Streiff, Eleni Gavriilaki, Ravi Kumar Alluri, Hang Chen, Keith R. McCrae, Shruti Chaturvedi, Alice Alexander, Mark Crowther, Evan M. Braunstein, Jia Yu
Publikováno v:
Blood. 135:239-251
The antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy morbidity in the presence of antiphospholipid antibodies, including anti-β2-glycoprotein-I (anti-β2GPI), that are considered central to APS pathogenesis. Based on a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f176aab376db9bd90f261f1f59855671
https://doi.org/10.1182/blood.2019003863
https://doi.org/10.1182/blood.2019003863
Publikováno v:
Frontiers in Molecular Biosciences
Frontiers in Molecular Biosciences, Vol 8 (2021)
Frontiers in Molecular Biosciences, Vol 8 (2021)
Reactive oxygen species (ROS) generated under oxidative stress (OS) cause oxidative damage to RNA. Recent studies have suggested a role for oxidized RNA in several human disorders. Under the conditions of oxidative stress, mRNAs released from polysom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc6f715310776da781f49cf672944db
https://doi.org/10.3389/fmolb.2021.672988
https://doi.org/10.3389/fmolb.2021.672988
Autor:
Ravi Kumar Alluri, Keith R. McCrae
Publikováno v:
Blood
Reduced plasma fibrinolysis has been identified as a potential risk factor for venous thromboembolism (VTE), but the role of cell surface fibrinolysis in VTE is unknown. The annexin A2/S100A10 complex serves as a coreceptor for plasminogen and tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4decfcd663667de09a869411bfc77798
https://pubmed.ncbi.nlm.nih.gov/33512476
https://pubmed.ncbi.nlm.nih.gov/33512476
Autor:
R. Bharti, Amy Joehlin-Price, Peter G. Rose, Ravi Kumar Alluri, Emily Esakov, Keith R. McCrae, C. Braley, Goutam Dey, Katie K. Crean-Tate, J. D. Lathia, Ofer Reizes, Gong Z
Poly-ADP Ribose Polymerase (PARP) inhibitors are clinically approved for the treatment of homologous recombination (HR) repair deficient tumors. PARP targeted therapy has limited efficacy in HR-proficient cancer. In this study, we identified the non-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a3af9d6a32361b0f09cbfd8d43a7551
https://doi.org/10.1101/2021.03.03.433791
https://doi.org/10.1101/2021.03.03.433791
Autor:
Paolo Macor, Vittorio Pengo, Ravi Kumar Alluri, Nicola Pozzi, Mathivanan Chinnaraj, Eliza A. Ruben, Keith R. McCrae, William Planer, Vincenzo De Filippis, Francesco Tedesco, Xiaobing Zuo, Zhiwei Chen
Venous and arterial thromboses in patients suffering from the autoimmune disorder Antiphospholipid Syndrome (APS) are caused by the presence of antiphospholipid antibodies (aPL). Emerging evidence indicates that autoantibodies targeting the epitope R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3b0c8f5c95e1b61ddd5c14122f8c07
https://doi.org/10.1101/2020.02.25.963314
https://doi.org/10.1101/2020.02.25.963314
Autor:
Mathivanan Chinnaraj, Zhiwei Chen, Francesco Tedesco, Vittorio Pengo, Eliza A. Ruben, William Planer, Vincenzo De Filippis, Xiaobing Zuo, Nicola Pozzi, Paolo Macor, Ravi Kumar Alluri, Keith R. McCrae
Publikováno v:
J Biol Chem
β(2)-Glycoprotein I (β(2)GPI) is an abundant plasma protein displaying phospholipid-binding properties. Because it binds phospholipids, it is a target of antiphospholipid antibodies (aPLs) in antiphospholipid syndrome (APS), a life-threatening auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b5b2919cdacd56ef196bdcf2e6bae5a
https://hdl.handle.net/11368/2992297
https://hdl.handle.net/11368/2992297
Autor:
Ravi Kumar Alluri, Matthew Godwin, Gabriel L Forbes, Aatira Vijay, Suman Kundu, Shadi Swaidani, Alvin H. Schmaier, Scott J Cameron, Keith R. McCrae
Publikováno v:
Blood. 138:2083-2083
Introduction Antiphospholipid syndrome (APS) is an autoimmune disorder caused by "antiphospholipid" antibodies (aPL) directed against β2-glycoprotein I (β2GPI). Although β2GPI is proposed to have both anti- and procoagulant properties in vitro, it
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::777bbeceeb5add10ccb73a0eb0c876aa
https://doi.org/10.1182/blood-2021-149755
https://doi.org/10.1182/blood-2021-149755
Autor:
Andrew Wiechert, Awad Jarrar, Justin D. Lathia, Ravi Kumar Alluri, Keith R. McCrae, Feng Lin, Anastasia Chumakova, James S. Hale, J. Julie Kim, Analisa DiFeo, Ofer Reizes, Anil Belur Nagaraj, Haider Mahdi, Peter G. Rose, Praveena S. Thiagarajan, Yan Li, Vinay S. Rao, Caner Saygin, Robert Debernardo, Elizabeth V. Connor, Fadi W. Abdul-Karim, Chad M. Michener, Daniel J. Lindner, Yvonne Parker
Publikováno v:
The Journal of Experimental Medicine
CD55 is a membrane complement regulatory protein that attenuates complement-mediated cytotoxicity. Saygin et al. elucidate a new role for CD55 as a signaling hub for cancer stem cell self-renewal and cisplatin resistance pathways in endometrioid tumo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92e331671cde7268b627dffb3a35024a
https://doi.org/10.1084/jem.20170438
https://doi.org/10.1084/jem.20170438