Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ravi K. Ramachandran"'
Autor:
Ronald A. Seifert, Bernard S. Buetow, Wolfgang E. Kaminski, Jeffrey R. Crosby, Paul J. Martin, Elaine W. Raines, Daniel F. Bowen-Pope, Ravi K. Ramachandran, Per Lindahl, Christer Betsholtz
Publikováno v:
The American Journal of Pathology. 159:1869-1876
The hypothesis that wound repair is augmented by delivery of platelet-derived growth factor (PDGF) from platelets and macrophages is an attractive extrapolation from the known activities of PDGF in cell culture and in vivo. To test this hypothesis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305c6c10f1406de02d8f02d1f53efbd0
https://doi.org/10.1016/s0002-9440(10)63033-7
https://doi.org/10.1016/s0002-9440(10)63033-7
Autor:
Christopher A. Seid, Jenny M. George, Maria F. Gonzalez-Rimbau, Venkatesh Govindarajan, Craig R. Tomlinson, Ravi K. Ramachandran, Constantin N. Flytzanis
Publikováno v:
Nucleic Acids Research. 25:3175-3182
The extracellular matrix (ECM) has been shown to play an important role in development and tissue-specific gene expression, yet the mechanism by which genes receive signals from the ECM is poorly understood. The aboral ectoderm-specific LpS1-alpha an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc139328209246ddf4f722810edd8def
https://doi.org/10.1093/nar/25.15.3175
https://doi.org/10.1093/nar/25.15.3175
Autor:
Venkatesh Govindarajan, Craig R. Tomlinson, Ravi K. Ramachandran, J.A. Uzman, Athula H. Wikramanayake
Publikováno v:
Development. 124:2355-2364
Little is known about the cell signaling involved in forming the body plan of the sea urchin embryo. Previous work suggested that PDGF-like and EGF-like receptor-mediated signaling pathways are involved in gastrulation and spicu-logenesis in the Lyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d4a5901d3dc3e0640835b412397eeb7
https://doi.org/10.1242/dev.124.12.2355
https://doi.org/10.1242/dev.124.12.2355
Autor:
Jenny M. George, Haemin Lee, Venkatesh Govindarajan, Mark T. Kozlowski, Christopher A. Seid, Ravi K. Ramachandran, Amy K. Sater, Craig R. Tomlinson
Publikováno v:
Journal of Molecular Biology. 264:7-19
Expression of the aboral ectoderm-specific LpS1 gene in Lytechinus was used to study lineage-specific transcriptional regulation during sea urchin development. Band shift assays using anti-USF antibody showed that a USF-like protein bound the USF cor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b58657fbf822776a2256be50fafd9400
https://doi.org/10.1006/jmbi.1996.0619
https://doi.org/10.1006/jmbi.1996.0619
Autor:
Jenny M. George, Diane C. Shakes, Ravi K. Ramachandran, Venkatesh Govindarajan, Craig R. Tomlinson
Publikováno v:
Developmental Biology. 172:541-551
Growth factors and the extracellular matrix have been shown to fulfill vital developmental roles in many embryonic systems. Our hypothesis is that a developmental role played by the extracellular matrix in sea urchins may be the binding of a PDGF-lik
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ae49de7432e825a35fc29ebc7801983
https://doi.org/10.1006/dbio.1995.8059
https://doi.org/10.1006/dbio.1995.8059
Autor:
Timothy M. Willson, Ravi K. Ramachandran, Steven A. Kliewer, Scott S. Sundseth, James M. Way, William K. Gottschalk, Kathleen K. Brown, Traci Ann Mansfield, W. Wallace Harrington
Publikováno v:
Endocrinology. 142(3)
Peroxisome proliferator-activated receptor γ (PPARγ) agonists, including the glitazone class of drugs, are insulin sensitizers that reduce glucose and lipid levels in patients with type 2 diabetes mellitus. To more fully understand the molecular me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d465b5350c7b4ad0297f57fb45c3fba
https://pubmed.ncbi.nlm.nih.gov/11181544
https://pubmed.ncbi.nlm.nih.gov/11181544
Autor:
Christopher A. Seid, Venkatesh Govindarajan, Ravi K. Ramachandran, Sonali Patil, Craig R. Tomlinson
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 204(1)
The mechanisms underlying sea urchin gastrulation and spiculogenesis have been sought for decades. We have identified two growth factor signaling pathways that are involved in these developmental events. Antibodies against mammalian platelet-derived
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a88b50018cd0d15b3c66a2e3f2f02e1c
https://pubmed.ncbi.nlm.nih.gov/8563028
https://pubmed.ncbi.nlm.nih.gov/8563028
Publikováno v:
Mechanisms of development. 44(1)
Development and LpS1 transcription in Lytechinus embryos are arrested at the mesenchyme blastula stage when collagen deposition is inhibited by the lathrytic agent β-aminopropionitrile (BAPN) or by proline analogs. We found that human recombinant pl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0405458e06f362c81fc693f6ae2e34e6
https://pubmed.ncbi.nlm.nih.gov/8155573
https://pubmed.ncbi.nlm.nih.gov/8155573