Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ravi K. Bansal"'
Publikováno v:
Carcinogenesis. 23:949-958
Human Tp53 is normally a short-lived protein. Tp53 protein is stabilized and levels are increased in response to a variety of cellular stresses, including those induced by genotoxic anticancer drugs and environmental exposures. To engineer an efficie
Autor:
Gloria H. Su, Charles J. Yeo, Kathleen M. Murphy, Elizabeth A. Montgomery, Scott E. Kern, Ravi K. Bansal, Ralph H. Hruban
Publikováno v:
Proceedings of the National Academy of Sciences. 98:3254-3257
DPC4 is known to mediate signals initiated by type β transforming growth factor (TGFβ) as well as by other TGFβ superfamily ligands such as activin and BMP (bone morphogenic proteins), but mutational surveys of such non-TGFβ receptors have been n
Publikováno v:
Molecular Carcinogenesis. 26:37-43
DPC4/SMAD4 is a candidate tumor suppressor gene with a strikingly high frequency of gene alterations in pancreatic cancer that suggests a discrete role for DPC4 in these tumors. DPC4 tumor-suppressive function has been implicated to mediate the trans
Autor:
Charles J. Yeo, Michael Goggins, Manu C. Shekher, Ravi K. Bansal, Gloria H. Su, Mark M. Entius, Anne Marie Westerman, David J. Tang, Ralph H. Hruban, Scott E. Kern, G. Steven Bova
Publikováno v:
The American Journal of Pathology. 154:1835-1840
Peutz-Jeghers syndrome (PJS) is an autosomal-dominant disorder characterized by hamartomatous polyps in the gastrointestinal tract and by pigmented macules of the lips, buccal mucosa, and digits. Less appreciated is the fact that PJS also predisposes
Autor:
Paula M, Hempen, Lin, Zhang, Ravi K, Bansal, Christine A, Iacobuzio-Donahue, Kathleen M, Murphy, Anirban, Maitra, Bert, Vogelstein, Robert H, Whitehead, Sanford D, Markowitz, James K V, Willson, Charles J, Yeo, Ralph H, Hruban, Scott E, Kern
Publikováno v:
Cancer research. 63(5)
The activin signaling pathway parallels the transforming growth factor (TGF)-beta pathway. Both use extracellular ligands and cell surface receptors that are structurally and functionally related, as well as the same intracellular mediators (SMADs 2-