Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ravi K, Bhamidipati"'
Autor:
Amol Magdum, Anil Panmand, Ravi K. Bhamidipati, Amol A. Raje, Vamsi Madgula, Ganesh Bhat, Meena Patel, Sreekanth R. Rouduri, Siddhartha De, Yogesh D. Shejul, Rajesh Bonagiri, Vandna Prasad, Anita Chugh, Ashwinkumar V. Meru, Vidya Ramdas, Sujay Basu, Dinesh A. Barawkar, Venkata P. Palle, Azfar Quraishi, Narayanan Hariharan, Sumit Chaudhary, Kasim A. Mookhtiar, Indraneel Ghosh, Minakshi Naykodi, K. Kashinath, Sachin Thorat
Publikováno v:
ACS Medicinal Chemistry Letters. 8:835-840
Adenosine A2A receptor (A2AAdoR) antagonism is a nondopaminergic approach to Parkinson's disease treatment that is under development. Earlier we had reported the therapeutic potential of 7-methoxy-4-morpholino-benzothiazole derivatives as A2AAdoR ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b859d65370dfe38949bf73f0a518820a
https://doi.org/10.1021/acsmedchemlett.7b00175
https://doi.org/10.1021/acsmedchemlett.7b00175
Autor:
Azfar Quraishi, Anita Chug, Suraj Menon, Vishal Unadkat, Sujay Basu, Madhav S. Seervi, Vandna Prasad, Sumit Chaudhary, Yogesh D. Shejul, Ganesh Bhat, Sachin Thorat, Ravi K. Bhamidipati, Shariq S. Ansari, Ashwinkumar V. Meru, Rhishikesh Thakare, Kasim A. Mookhtiar, Yogesh Salve, Venkata P. Palle, Minakshi Naykodi, Siddhartha De, Vaibhav Jain, Harish Patil, Indraneel Ghosh, Dinesh A. Barawkar, Meena Patel, Sreekanth R. Rouduri
Publikováno v:
Journal of Medicinal Chemistry. 60:681-694
Our initial structure–activity relationship studies on 7-methoxy-4-morpholino-benzothiazole derivatives featured by aryloxy-2-methylpropanamide moieties at the 2-position led to identification of compound 25 as a potent and selective A2A adenosine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04044ccde58cf238c9369505eaf87036
https://doi.org/10.1021/acs.jmedchem.6b01584
https://doi.org/10.1021/acs.jmedchem.6b01584
Autor:
Sujay, Basu, Dinesh A, Barawkar, Vidya, Ramdas, Minakshi, Naykodi, Yogesh D, Shejul, Meena, Patel, Sachin, Thorat, Anil, Panmand, K, Kashinath, Rajesh, Bonagiri, Vandna, Prasad, Ganesh, Bhat, Azfar, Quraishi, Sumit, Chaudhary, Amol, Magdum, Ashwinkumar V, Meru, Indraneel, Ghosh, Ravi K, Bhamidipati, Amol A, Raje, Vamsi L M, Madgula, Siddhartha, De, Sreekanth R, Rouduri, Venkata P, Palle, Anita, Chugh, Narayanan, Hariharan, Kasim A, Mookhtiar
Publikováno v:
ACS medicinal chemistry letters. 8(8)
Adenosine A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::54aaa72e45a440806a9999ba7b800c85
https://pubmed.ncbi.nlm.nih.gov/28835798
https://pubmed.ncbi.nlm.nih.gov/28835798
Autor:
Sujay, Basu, Dinesh A, Barawkar, Sachin, Thorat, Yogesh D, Shejul, Meena, Patel, Minakshi, Naykodi, Vaibhav, Jain, Yogesh, Salve, Vandna, Prasad, Sumit, Chaudhary, Indraneel, Ghosh, Ganesh, Bhat, Azfar, Quraishi, Harish, Patil, Shariq, Ansari, Suraj, Menon, Vishal, Unadkat, Rhishikesh, Thakare, Madhav S, Seervi, Ashwinkumar V, Meru, Siddhartha, De, Ravi K, Bhamidipati, Sreekanth R, Rouduri, Venkata P, Palle, Anita, Chug, Kasim A, Mookhtiar
Publikováno v:
Journal of medicinal chemistry. 60(2)
Our initial structure-activity relationship studies on 7-methoxy-4-morpholino-benzothiazole derivatives featured by aryloxy-2-methylpropanamide moieties at the 2-position led to identification of compound 25 as a potent and selective A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6669e08bb0eb3701d249b4c3c0ab153e
https://pubmed.ncbi.nlm.nih.gov/28055204
https://pubmed.ncbi.nlm.nih.gov/28055204
Autor:
Francis C. K. Chiu, David M. Shackleford, Susan A. Charman, Julia Morizzi, Ravi K. Bhamidipati
Publikováno v:
Journal of Chromatography B. 877:2989-2995
OZ277 is a synthetic 1,2,4-trioxolane antimalarial currently being evaluated in clinical trails. Biotransformation of OZ277 in rats results in the generation of metabolites with large differences in polarity which complicates the development of a met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db142601bd7c05aa6edce0c64f41adf7
https://doi.org/10.1016/j.jchromb.2009.07.015
https://doi.org/10.1016/j.jchromb.2009.07.015
Autor:
Karen L. White, David M. Shackleford, Sergio Wittlin, Mohammed K Zabiulla, Jayan T. Joseph, Aloysius T. Nchinda, Sridevi Bashyam, Claire Le Manach, David J. Hardick, Susan A. Charman, Vicky M. Avery, Yassir Younis, Ravi K. Bhamidipati, Frederic Douelle, Michael J Witty, Tzu-Shean Feng, Kelly Chibale, Diego Gonzàlez Cabrera, David Waterson, Kasiram Katneni, Julia Morizzi, Janne Mannila, Sandra Duffy
Publikováno v:
Journal of medicinal chemistry. 55(7)
A novel class of orally active antimalarial 3,5-diaryl-2-aminopyridines has been identified from phenotypic whole cell high-throughput screening of a commercially available SoftFocus kinase library. The compounds were evaluated in vitro for their ant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca7e4c449ccc405be52573d52ea13bc0
https://pubmed.ncbi.nlm.nih.gov/22390538
https://pubmed.ncbi.nlm.nih.gov/22390538
Autor:
Kasiram Katneni, Sreekanth Kokkonda, Susan A. Charman, Elizabeth J. Goldsmith, Jeremy N. Burrows, María Belén Jiménez-Díaz, Ravi K. Bhamidipati, Margaret A. Phillips, William N. Charman, Xiaoyi Deng, Iñigo Angulo-Barturen, David M. Floyd, Jose M. Coteron, David Matthews, Francisco-Javier Gamo, Jorge Esquivias, Pradipsinh K. Rathod, John H. White, Farah El Mazouni, Karen L. White, Santiago Ferrer, David M. Shackleford, Maria Koltun, Maria L. Marco, Ian Bathurst
Publikováno v:
Journal of medicinal chemistry. 54(15)
Drug therapy is the mainstay of antimalarial therapy, yet current drugs are threatened by the development of resistance. In an effort to identify new potential anti-malarials we have undertaken a lead optimization program around our previously identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7c1dee444ff5d3b96693e69fe178114
https://pubmed.ncbi.nlm.nih.gov/21696174
https://pubmed.ncbi.nlm.nih.gov/21696174